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Active clinical trials for "Aortic Aneurysm, Abdominal"

Results 1-10 of 419

Alpha-Ketoglutarate and Abdominal Aortic Aneurysm Progression and Rupture

Patients With an Abdominal Aortic Aneurysm of 39-49 mm in Diameter

The objective of this project is to define whether nutritional supplement (oral administration with alpha-ketoglutarate) capable of filling-up the citric acid cycle (anaplerotic therapy) can improve outcomes in patients with an abdominal aortic aneurysm of 39-49 mm in diameter on ultrasound imaging. Alpha-ketoglutarate is commonly used as a nutritional supplement specially by athletes to increase muscle strength. They can be mixed with formula or other foods. Subjects will be followed for up to 5 years.

Recruiting18 enrollment criteria

Safety and Efficacy of Endovascular Repair of Complex Aortic Pathology With Physician-modified Endovascular...

Abdominal Aortic AneurysmThoracoabdominal Aortic Aneurysm1 more

The primary objective of this study is to examine the safety and effectiveness of physician-modified endovascular grafts (PMEGs) for endovascular repair of complex aortic pathology in high-risk patients. The study is divided into three study arms based on the subject's aortic pathology: (1) Complex abdominal aortic aneurysm (AAA); (2) Thoracoabdominal aortic aneurysm; and (3) Aortic dissection.

Recruiting52 enrollment criteria

ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES

Aortic AneurysmAbdominal

The aim of this randomized study is to compare the safety and performance of EndoVascular Aneurysm Repair with ESAR using Endurant + Heli-FX™ EndoAnchor™ system and FEVAR using customizable grafts from Cook (Zenith Fenestrated Graft) and Terumo (Fenestrated Anaconda Graft) for the treatment of aortic aneurysms with short aortic neck (4 to 15mm).

Recruiting27 enrollment criteria

ANEUFIX for Endoleak Type II Repair

Abdominal Aortic AneurysmEndoleak

The study is non-randomized, multicenter international safety, performance and clinical benefit outcome assessment of ANEUFIX to treat patients with isolated type II endoleak in the presence of a growing AAA-sac following an EVAR procedure more than 6 months ago.

Recruiting19 enrollment criteria

ACT Guided Heparinization During Open Abdominal Aortic Aneurysm Repair.

Abdominal Aortic AneurysmSurgery1 more

Aim of the ACTION-1 study is to determine whether ACT guided heparinization decreases thrombo-embolic complications (TEC) and mortality after elective open AAA surgery, without causing more bleeding complications.

Recruiting16 enrollment criteria

Safety and Efficacy Study of WeFlow-JAAA Stent Graft System for Complex Abdominal Aortic Aneurysm(GREAT...

Juxtarenal Abdominal Aortic Aneurysm

A prospective, multi-center, objective performance criteria clinical trial to evaluate the safety and efficacy of WeFlow-JAAA stent graft system manufactured by Hangzhou Endonom Medtech Co., Ltd. for the complex abdominal aortic aneurysm.

Recruiting29 enrollment criteria

JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

AAAAAA - Abdominal Aortic Aneurysm

Prospective, randomized, multi-center study designed to evaluate the outcomes of commercially available contemporary EVAR in a real-world population. Patients will be randomized into two device cohorts and compared across the primary endpoints. Patients will be followed procedurally to discharge, at 1, 6, 12 months and annually through to 5 years (total follow-up commitment).

Recruiting12 enrollment criteria

Endovascular Exclusion of Thoracoabdominal and/or Paravisceral Abdominal Aortic Aneurysm

Thoracoabdominal Aortic AneurysmParavisceral Abdominal Aortic Aneurysm

This is a study to assess the safety and effectiveness of endovascular treatment of thoracoabdominal (TAAA) and paravisceral abdominal (PVAAA) aortic aneurysms. The investigational operation involves placing a stent-graft over the aortic aneurysm.

Recruiting16 enrollment criteria

A Non-Traumatic Binder for Temporary Abdominal Wall Closure

Abdominal TraumaAbdominal Injury6 more

At the end of most abdominal operations, the fascial layer is closed by stitching edges of the wound together. However, because of logistic and/or technical reasons or the patient's critical condition, the surgeon is forced to leave the abdomen open. The current approach for temporary coverage of abdomen is vacuum assisted techniques (VAT). This technique requires the use of vacuum-assisted drainage to remove blood or watery fluid from a wound or operative site. Although this is the most successful and commonly used procedure, there are some limitations to this method. For example, VAT have little effect on preventing lateral movement of the wound edges. Therefore, VAT it is not the ideal procedure in aiding surgeons to closed the abdomen. The purpose of this study is to compare usual care (vacuum or non-vacuum methods for temporary coverage of the OA) versus usual care plus a novel new abdominal binder device called ABRO™ that may aid in the closure of patients who undergo open abdomen closure procedures.

Recruiting6 enrollment criteria

Post-Approval Study of the TREO Abdominal Stent-Graft System

Abdominal Aortic Aneurysm

The purpose of this study is to determine the long-term performance of the TREO Abdominal Stent-Graft as a treatment for patients with Infrarenal Abdominal Aortic Aneurysms or Aorto-iliac Aneurysms.

Recruiting5 enrollment criteria
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