Decision Support Intervention Adapted for HIV Pre-Exposure Prophylaxis for Adoption and Adherence...
HIV/AIDSAim 1: Adapt Ottawa Decision Support Framework for the HIV PrEP decisional needs of African, Caribbean and Black (ACB) Canadian patients Aim 2. Pilot Test The Adapted Decision-Support Intervention Using a Two-Arm Randomized Controlled Design
Mindful Living With Stress for Nurses Caring for HIV/AIDS Patients in China
StressThe primary objective of this proposed one-year (January 01, 2017 to December 31,2017) project is to assess whether a mindfulness based intervention('Mindful Living With Stress') will be effective at helping nurses caring for HIV/AIDS patients in China to reduce stress. Based on the efficacy of previous studies in stress reduction, it is hypothesized that 'Mindful Living With Stress' will be an effective, feasible and affordable stress reduction program in China.
Monitoring Pre-exposure Prophylaxis for Young Adult Women
HIV/AIDSAdherenceNext generation real-time monitoring for PrEP adherence in young Kenyan women
Friends for Life Circles for Option B Plus
Human Immunodeficiency VirusThe main goal of the study is to support HIV-infected pregnant women initiated on PMTCT Option B+ during antenatal to adhere to lifelong ART and postpartum care visits through an enhanced group peer support intervention called "friends for life circles".
Inflammatory Pathogenesis of Coronary Atherosclerosis in HIV
Coronary Artery DiseaseHuman Immunodeficiency VirusThe investigators are studying whether an anti-inflammatory intervention improves impaired coronary endothelial function (CEF) in HIV+ people with no clinical coronary artery disease (CAD).
A Trial to Assess the Functionality of Female Condom With a Silicone Elastomer Vaginal Ring
Human Immunodeficiency VirusA multi-center, open-label, randomized, two-period, crossover non-inferiority trial to assess the functionality of female condoms with a silicone elastomer vaginal ring.
Pre-ART Retention in Care in Tanzania
HIV (Human Immunodeficiency Virus)AIDS (Acquired Immunodeficiency Syndrome)Retention of patients in HIV care following diagnosis and enrollment is critical to the long-term success of HIV care and treatment scale-up. The goal of this study is to better understand the factors that influence retention and engagement in HIV care among adult patients who are enrolled in HIV care and are not yet eligible for antiretroviral therapy (ART). The study will be conducted at four HIV care and treatment clinics (CTCs) in Kagera Region, Tanzania. This is a mixed-methods study with both qualitative (interviews) and quantitative (surveys) data collection. Our findings will be important towards designing programs that help patients remain in HIV care.
Quantifying Drug Adherence and Drug Exposure to Antiretroviral Therapy
HIV/AIDSThe purpose of this study is to evaluate cumulative exposure to tenofovir diphosphate (TFV-DP) using dried blood spots (DBS) in treated HIV-infected patients who are receiving a TFV-based regimen. Using DBS will allow the investigators to assess this simple method to measure drug exposure in the clinical setting. The investigators hypothesize that TFV-DP levels will be lowest in individuals with a detectable viral load and highest in those with viral suppression.
Novel Therapy for Glucose Intolerance in HIV Disease
Insulin ResistanceThis research is to investigate the nutritional supplement chromium picolinate. The investigators are testing to see how effective this supplement is in treating insulin resistance associated with HIV disease.
Impact of Hepatitis C Virus Therapy on Central Nervous System Outcomes
Hepatitis CHuman Immunodeficiency VirusThis study observes the effects of newly developed direct-acting antiviral (DAA) treatments on the central nervous system (CNS) of individuals with chronic Hepatitis C (HCV). The goals of this study are to determine the CNS impact of curing chronic HCV disease with newly established DAA therapies and how HIV alters this relationship.