Histopathology of the Aspirated Thrombus During Acute Myocardial Infarction
ThrombosisAcute Coronary SyndromeThis study was initiated on the preliminary premise that a thrombus whose formation was triggered by a thrombogenic substrate, such as within an atherosclerotic plaque (Tissue factor initiated thrombus), may evolve differently than the one evolving at the site of a recently implanted stent (foreign body triggered). Consequently, the thrombus composition of a de novo clot could differ from the other one, extracted during the occurrence of a subacute thrombosis, regarding the number of various cells, the amount of fibrin and platelet aggregates and the relationship among these components. In addition, it seems relevant to evaluate the numbers and the distribution of the local monocytes, once these cells may interact with platelets (via cell -adhesion mechanisms e.g., by CD31 [PECAM-1]) and by the extrinsic coagulation pathway (via TF/FVII elaborated by plaque-resident macrophages). Such a distinction, if eventually found, may reveal the mechanisms of thrombosis within coronary arteries, and may have clinical implications.
Timing of Optimal Platelet Inhibition After Acute Coronary Syndrome
Acute Coronary SyndromeCoronary Stenting1 moreComparison of two antiplatelet strategies between months 1 and 12 after coronary stenting for ACS. Efficiency and tolerance évaluation
Registry of Acute Coronary Syndromes in the Lazio Region of Italy
Acute Coronary SyndromesThe NET-SCA Registry has been designed to document and evaluate the clinical epidemiology and current management of Acute Coronary Syndromes in the Lazio Region of Italy.
Real World Assessment of Effects of Beta-blockers on Patients With Acute Coronary Syndrome
Acute Coronary SyndromeThe study is aimed to optimized the dose-adjusted regimen of beta-blockers in patients with acute coronary syndrome by investigating therapeutic and curative results of target doses Beta-blockers using the dose-adjusted pathway of beta-blockers.
Recurrent Events After Percutaneous Coronary INterventio for ACS
Coronary Artery DiseaseAcute Coronary SyndromePatients undergoing PCI for ACS are exposed to a significant ischemic and bleeding risk. The aim of our study is instead to analyze in detail the rates of recurrent events, but also their predictors and impact on outcomes, in a population of unselected real life patients treated with PCI for ACS discharged on either Clopidogrel, Prasugrel or Ticagrelor who already experienced an adverse event during the first year of follow up.
A Survey of Hospitalizations in Cardiology Units in Sub-Saharan Africa
Acute Coronary SyndromeHeart Failure9 moreFEVRIER study is an observatory of hospitalizations in cardiology units in sub-Saharan Africa.
Observatory on Emergency Care for Acute Coronary Syndrome in Grand Est of France
Acute Coronary SyndromeThe purpose is to build up a data observatory of individuals with thoracic pain evoking acute coronary syndrome (ACS). The aim is the characterization of this population of patients consulting at emergency department, the evaluation of therapeutic strategies with regard to guidelines and the becoming of patients including severe complications and mortality.
OCT-Features in Culprit and Not Culprit Coronary Plaque in ACS Patients
Acute Coronary SyndromeCulprit Plaque1 moreThe OCT-FORMIDABLE register will include with a retrospective fashion all consecutive patients that perform OCT on culprit and not culprit plaque in any subset in patients with ACS. Clinical and OCT data will be included in the register according to the dataset.The primary endpoint will be the correlation of OCT characteristics with incidence of major adverse cardiovascular events (MACEs defined as the composite of death from cardiac causes, non- fatal MI, clinically driven target vessel revascularization (TVR), or re-hospitalization due to unstable or progressive angina according to Braunwald Unstable Angina Classification) and clinical baseline characteristics. In particular subanalysis will be performed in the following subgroups: culprit plaque, not culprit plaque in culprit vessel, not culprit plaque in different vessel. Secondary end-point will be to evaluate how OCT analysis changed interventional cardiology approach in culprit plaque definition and coronary stenting respect the coronary angiography alone.
Potential Diagnostic and Prognostic Value of microRNAs for the Patients of Acute Coronary Syndrome...
Acute Coronary SyndromeThe purpose of this study is to evaluate the potential diagnostic and prognosis value of circulating microRNAs compared with cTnI for suspected ACS patients at the emergency department (ED) and intensive care unit (ICU).
French Registry of Acute Coronary Syndrome
Acute Myocardial InfarctionThe Fast-MI registry was designed to evaluate the "real world" management of patients with acute myocardial infarction (MI), and to assess their in-hospital, medium and long-term outcomes