
Safety and Tolerability of E5555 and Its Effects on Markers of Intravascular Inflammation in Subjects...
Acute Coronary SyndromeThis is a multi-center, randomized, double-blind, placebo-controlled study to determine the safety and tolerability of E5555 in subjects with Acute coronary syndrome (ACS).

Early Versus Delayed Timing of Intervention in Patients With Acute Coronary Syndromes
Unstable AnginaMyocardial InfarctionThe timing of intervention study is a prospective, randomized, international, multicentre comparison of the relative efficacy, safety, and cost effectiveness of a management strategy of coronary angiography and intervention performed within 24 hours of randomization versus delayed coronary angiography and intervention in patients after 36 hours with acute coronary syndromes (ACS).

A Double-Blind Study of E5555 in Japanese Patients With Acute Coronary Syndrome
Acute Coronary SyndromeThe purpose of this study is to assess the safety and tolerability of E5555 in Japanese patients with acute coronary syndrome.

A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome Subjects
Acute Coronary SyndromeThis study will evaluate the relative efficacy and safety of prasugrel and clopidogrel in a medically managed Unstable Angina/Non-ST-Elevation Myocardial Infarction (UA/NSTEMI) acute coronary syndrome (ACS) population (that is, patients who are not managed with acute coronary revascularization).

FRANCIS-ACS Trial: A Study of the Safety and Efficacy of A 002 in Subjects With Acute Coronary Syndromes...
Acute Coronary SyndromeThe objective of this study is to evaluate the safety and efficacy of A 002 when added to high dose atorvastatin in subjects with an acute coronary syndrome (ACS)

Intravenous Exenatide in Coronary Intensive Care Unit (ICU) Patients
HyperglycemiaAcute Coronary Syndromes1 moreThe purpose of this study is to determine the efficacy of intravenous Exenatide therapy in hyperglycemic patients admitted to the coronary intensive care unit.

Effects in The ApoB/ApoA-I Ratio Using Rosuvastatin and Atorvastatin in Patients With Acute Coronary...
Acute Coronary SyndromeThe purpose of this study is to see if rosuvastatin compared to Atorvastatin is effective in treating ACS by decreasing the ApoB/ApoA-1 ratio and if starting statin within 24 h following the onset of the first symptoms is beneficial compared to placebo.

Effect of Prasugrel on Platelets After One Week in Patients Already Taking Clopidogrel After a Cardiac...
Coronary ArteriosclerosisAcute Coronary SyndromeThis study will compare the effect of a prasugrel 10-mg maintenance dose with a clopidogrel 75-mg maintenance dose on platelet activity, approximately 1 week after the first dose of study drug, in subjects who have been taking clopidogrel 75 mg daily following a percutaneous coronary intervention (PCI) with placement of a stent, performed to treat acute coronary syndrome (ACS).

A Study to Evaluate the Safety of 12 Weeks of Dosing With GW856553 and Its Effects on Inflammatory...
Acute Coronary SyndromeThis is a randomized, double-blind, placebo-controlled, parallel group, multi-center study to evaluate initial safety and efficacy of GW856553 in subjects with NSTEMI. Up to approximately 525 subjects will be randomized to meet the MRI recruitment target (90 subjects in substudy.) All subjects will continue to receive the local standard of care for the duration of the study.

A Trial of Inflammatory Markers, Depressive Symptoms, and Heart Disease
DepressionCoronary Artery Disease (CAD)1 moreThe purpose of this study is to examine the relationship between depressive symptoms and markers of inflammation, two predictors of heart disease.