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Active clinical trials for "Acute Coronary Syndrome"

Results 301-310 of 1231

Safety and Tolerability of E5555 and Its Effects on Markers of Intravascular Inflammation in Subjects...

Acute Coronary Syndrome

This is a multi-center, randomized, double-blind, placebo-controlled study to determine the safety and tolerability of E5555 in subjects with Acute coronary syndrome (ACS).

Completed9 enrollment criteria

Early Versus Delayed Timing of Intervention in Patients With Acute Coronary Syndromes

Unstable AnginaMyocardial Infarction

The timing of intervention study is a prospective, randomized, international, multicentre comparison of the relative efficacy, safety, and cost effectiveness of a management strategy of coronary angiography and intervention performed within 24 hours of randomization versus delayed coronary angiography and intervention in patients after 36 hours with acute coronary syndromes (ACS).

Completed10 enrollment criteria

A Double-Blind Study of E5555 in Japanese Patients With Acute Coronary Syndrome

Acute Coronary Syndrome

The purpose of this study is to assess the safety and tolerability of E5555 in Japanese patients with acute coronary syndrome.

Completed10 enrollment criteria

A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome Subjects

Acute Coronary Syndrome

This study will evaluate the relative efficacy and safety of prasugrel and clopidogrel in a medically managed Unstable Angina/Non-ST-Elevation Myocardial Infarction (UA/NSTEMI) acute coronary syndrome (ACS) population (that is, patients who are not managed with acute coronary revascularization).

Completed14 enrollment criteria

FRANCIS-ACS Trial: A Study of the Safety and Efficacy of A 002 in Subjects With Acute Coronary Syndromes...

Acute Coronary Syndrome

The objective of this study is to evaluate the safety and efficacy of A 002 when added to high dose atorvastatin in subjects with an acute coronary syndrome (ACS)

Completed27 enrollment criteria

Intravenous Exenatide in Coronary Intensive Care Unit (ICU) Patients

HyperglycemiaAcute Coronary Syndromes1 more

The purpose of this study is to determine the efficacy of intravenous Exenatide therapy in hyperglycemic patients admitted to the coronary intensive care unit.

Completed19 enrollment criteria

Effects in The ApoB/ApoA-I Ratio Using Rosuvastatin and Atorvastatin in Patients With Acute Coronary...

Acute Coronary Syndrome

The purpose of this study is to see if rosuvastatin compared to Atorvastatin is effective in treating ACS by decreasing the ApoB/ApoA-1 ratio and if starting statin within 24 h following the onset of the first symptoms is beneficial compared to placebo.

Completed6 enrollment criteria

Effect of Prasugrel on Platelets After One Week in Patients Already Taking Clopidogrel After a Cardiac...

Coronary ArteriosclerosisAcute Coronary Syndrome

This study will compare the effect of a prasugrel 10-mg maintenance dose with a clopidogrel 75-mg maintenance dose on platelet activity, approximately 1 week after the first dose of study drug, in subjects who have been taking clopidogrel 75 mg daily following a percutaneous coronary intervention (PCI) with placement of a stent, performed to treat acute coronary syndrome (ACS).

Completed8 enrollment criteria

A Study to Evaluate the Safety of 12 Weeks of Dosing With GW856553 and Its Effects on Inflammatory...

Acute Coronary Syndrome

This is a randomized, double-blind, placebo-controlled, parallel group, multi-center study to evaluate initial safety and efficacy of GW856553 in subjects with NSTEMI. Up to approximately 525 subjects will be randomized to meet the MRI recruitment target (90 subjects in substudy.) All subjects will continue to receive the local standard of care for the duration of the study.

Completed30 enrollment criteria

A Trial of Inflammatory Markers, Depressive Symptoms, and Heart Disease

DepressionCoronary Artery Disease (CAD)1 more

The purpose of this study is to examine the relationship between depressive symptoms and markers of inflammation, two predictors of heart disease.

Terminated23 enrollment criteria
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