Social Deprivation and Initial Presentation of 12 Cardiovascular Diseases: a CALIBER Study
Abdominal Aortic AneurysmCoronary Heart Disease NOS13 moreStudy of heterogeneity in associations between social deprivation and the initial presentation of 12 cardiovascular diseases.
Electroencephalograph for Detection of Acute Ischemic Stroke
StrokeThe purpose of this study is Collecting data for an Electroencephalograph based algorithm for detection of onset and deterioration of Acute Ischemic Stroke by Comparison to NIHSS.
Heart and Ischemic STrOke Relationship studY
Brain IschemiaAcute Stroke1 moreAlthough cardio-embolic etiology of ischemic stroke (IS) is largely respected, there is still no clear recommendation for routine complex cardiological examination in all IS patients. Using complex cardiological examination the investigators expect: more accurate detection of patients with concomitant heart disease (cardiac rhythm disorder, valve disorders, acute coronary syndrome, cardiac thrombus and myxoma, atrial and ventricle septum defects) higher number of etiologically determinated IS, which is crucial for accurate secondary prevention.
Prognostic Significance of the Baroreflex Sensitivity Changes After Acute Ischemic Stroke
Cerebrovascular AccidentBaroreflexes1 moreAfter acute stroke, baroreflex sensitivity (BRS) is impaired. This impaired acute stage BRS has been reported to be predictive of worsen outcome years after stroke in general. However, it is not very clear if the impaired acute stroke BRS would actually persist months after the acute stage. It is also not clear that such change, if any, would correlate with the functional outcome or prognosis after stroke. The trial is to investigate the longitudinal time course of BRS after ischemic stroke up to the 6th month post stroke and to see if there is any correlation of the changes in BRS with the functional outcome parameters using NIHSS and mRS scores throughout this period.
Quality Assessment in Acute Stroke Care
Acute Ischemic StrokeThe purpose of the study is to evaluate the quality of care on a 16 bed stroke unit by using a new developed clinical pathway.
Serum Uric Acid Levels and Onset of Cardiovascular Diseases: a CALIBER Study
Stable AnginaUnstable Angina11 moreSerum uric acid level is a commonly measured biomarker. The association between serum uric acid level and the risk of developing cardiovascular diseases has been observed in some studies, while others showed controversial results. Estimation of this association may help to predict cardiovascular outcomes and may guide new treatment strategies. The hypothesis is that increased serum uric acid level is associated with a range of cardiovascular diseases.
Predictive Factors of Outcome of Mechanical Thrombectomy After Acute Ischemic Stroke
Acute Ischemic StrokePredictive factors of outcome of mechanical thrombectomy after acute ischemic stroke
Perfusion and Collaterals Imaging With C-arm CT
Ischemic StrokeSingle-center, single-arm pilot study to evaluate the ability of C-arm computed tomography imaging to assess perfusion parameters, collateral vessels, recanalization and brain ischemia in patients with suspected or proven ischemic stroke or brain ischemia in the neuro-angiography suite.
Clopidogrel Resistance in Stroke Patients From Different Ethnicities
ClopidogrelPoor Metabolism of1 moreClopidogrel is an anti-platelet agent used to inhibit blood clots. Variation in response to clopidogrel has been reported among different population and may lead to reoccurring ischemic events. The aim of the present study is to evaluate the incidence of clopidogrel resistance in ischemic stroke patients from different ethnicities in Northern Israel and to find different strategies to overcome high platelet reactivity including clopidogrel dose adjustment or the choice of alternative agents. Quantification of platelet aggregation will be determined by vasodilator stimulated phosphoprotein (VASP) assay.
The Prevalence of a Low Ankle-Brachial Index in Acute Cerebral Ischemia.
Ischemic StrokeAim of the study is assessment the prevalence of the low ankle-brachial index (ABI) defined less than or equal 0.9 in patients with acute cerebral ischemic event (stroke or transient ischemic attack) and determinate the correlation between ABI and internal carotid artery stenosis (ICAS) in the acute cerebral ischemic patients. The low ABI is a strong marker of generalized atherosclerosis. LEAD is a strong independent predictor for stroke.