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Active clinical trials for "Acute Kidney Injury"

Results 1131-1140 of 1194

Citrate Pharmacokinetics and Regional Citrate Anticoagulation in CRRT

Acute Kidney Failure With or Without:MODS2 more

To compare the differences of citrate pharmacokinetics in healthy individuals and critically ill patients as well as the influential factors. To validate a pharmacokinetic model which has been established in a formal paper. To create a safe and effective RCA-CRRT protocol.

Unknown status10 enrollment criteria

2012_PharmacoCRRT-study:Pharmacokinetics of Anti-infectives in Critically Ill Patients in Need of...

Critically IllAcute Renal Failure1 more

The main purpose of the study is to examine if changes in pharmacokinetics of important antiinfectives in Critically Ill patients in need of continuous renal replacement therapy (CRRT), causes inadequate concentrations in plasma. The effect of different modus of CRRT: CVVH and CVVHD will be compared, as well as type of filter, filter lifetime etc. Hypothesis: The risk of incorrect dosage of antiinfectives - to low/ to high- is increased in critically ill patients receiving CRRT. Inadequate plasma concentrations of antiinfectives may contribute to increased mortality in this group.

Unknown status8 enrollment criteria

Severe Sepsis in Children - IMPRESS-C

Acute Kidney InjuryChronic Kidney Disease1 more

Sepsis is the most common cause of childhood death worldwide. Millions of children survive, but are left with impaired health. Sepsis-related Acute Kidney Injury (sAKI) is increasingly recognized as a significant factor associated with long-term mortality among different patient populations. Renal dysfunction and subsequent chronic kidney disease is implicated in the development of hypertension and cardiovascular disease. The investigators overall hypothesis is that, in the pediatric population, sepsis-related AKI will have unrecognized, long-term consequences with regard to kidney function, endothelial function, blood pressure control, and overall health.

Withdrawn23 enrollment criteria

Hematologic Ratios in Postoperative Acute Kidney Injury

Acute Kidney Injury

Acute kidney injury (AKI) is a common complication after surgery for congenital heart disease and is associated with significant morbidity and mortality. To-date, no biomarker has been universally implemented for predicting AKI in neonates after cardiac surgery. In this study, the use of hematological ratios will be evaluated for predicting AKI and postoperative outcomes in this patient cohort.

Withdrawn9 enrollment criteria

A Zero Acute Kidney Injury Strategy for Percutaneous Coronary Intervention in Patients With ChronicKidney...

Acute Kidney InjuryCoronary Artery Disease1 more

The purpose of this study is to compare the outcomes of Percutaneous Coronary Intervention (PCI) in patients with chronic kidney disease (CKD) using smaller doses of contrast dye that are validated as being at low risk of causing injury to the kidneys, with the larger doses that are traditionally used contemporary practice.

Withdrawn16 enrollment criteria

Time to Excretion of Contrast, a Maastricht Prospective Observational Study

Renal InsufficiencyAcute Kidney Injury1 more

Risk of contrast-induced kidney injury is expected to be strongly correlated with exposure time. Studies on the excretion of iodinated contrast material are few and have mostly been carried out in patients with normal renal function. Although case wise reports of persistent renograms have been published, it is not known how long contrast is retained before excretion in patients with eGFR <30 mL/min/1.73m2, nor which of these patients are most susceptible to contrast retention. The current observational study aims to compare contrast elimination time and % contrast excretion in patients with eGFR <30 mL/min/1.73m2, to matched patients (for age, sex and contrast procedure type) with eGFR 30-59 and eGFR >=60 mL/min/1.73m2.

Withdrawn8 enrollment criteria

New Urine and Blood Markers for Acute Kidney Injury in Liver Transplant Patients

Renal InsufficiencyAcute

The purpose of this study is to find new blood and urine tests that detect acute kidney injury earlier than our current blood tests in patients receiving a liver transplant.

Withdrawn7 enrollment criteria

Impact of Pediatric Acute Renal Injury in Severe Sepsis in Young Adults

Acute Kidney InjuryChronic Kidney Disease1 more

Sepsis is the most common cause of childhood death worldwide. Millions of children survive, but are left with impaired health. Sepsis-related Acute Kidney Injury (sAKI) is increasingly recognized as a significant factor associated with long-term mortality among different patient populations. Renal dysfunction and subsequent chronic kidney disease is implicated in the development of hypertension and cardiovascular disease. The investigators overall hypothesis is that, in the pediatric population, sepsis-related AKI will have unrecognized, long-term consequences with regard to kidney function, endothelial function, blood pressure control, and overall health.

Withdrawn18 enrollment criteria

Long Term Impact of Pediatric Acute Renal Injury in Severe Sepsis

Acute Kidney InjuryChronic Kidney Disease1 more

Sepsis is the most common cause of childhood death worldwide. Millions of children survive, but are left with impaired health. Sepsis-related Acute Kidney Injury (sAKI) is increasingly recognized as a significant factor associated with long-term mortality among different patient populations. Renal dysfunction and subsequent chronic kidney disease is implicated in the development of hypertension and cardiovascular disease. The investigators overall hypothesis is that, in the pediatric population, sepsis-related AKI will have unrecognized, long-term consequences with regard to kidney function, endothelial function, blood pressure control, and overall health.

Withdrawn21 enrollment criteria

New Prognostic Kidney Function Markers in Emergency Patients New Markers of Kidney Function in ED...

Acute Kidney InjuryContrast Media

NephroCheck is measuring the concentration of a certain protein combination in the urine of patients. In elevated values there is a probability of renal failure (already proven in intensive care patients). The investigators would like to investigate whether the investigators can predict renal failure in patients receiving contrast enhanced CT's in the emergency department. That would lead to an earlier nephrologist consult in those patients.

Withdrawn5 enrollment criteria
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