Extralevator Versus Standard Abdominoperineal Resection For Rectal Adenocarcinoma
Rectal AdenocarcinomaThis is a study that compares two types of surgery for rectal cancer. There are two procedures that can be used during this surgery, conventional abdominal resection (APR) and extended (or extralevator) APR. The investigators are doing this research to see whether the extralevator APR increases the likelihood that the edge of the tissue that is removed will be more likely to be free from cancer cells compared with the conventional APR surgery. At this time there is no evidence that one type of procedure is better at this than the other. The objective of this research is to determine whether extralevator APR is more likely to have clean margins (free of cancer) compared to the standard APR surgery.
Pancreatic Juice Diagnosis From Duodenum
Pancreatic AdenocarcinomaPurpose of this study is to understand the clinical feasibility of duodenal juice diagnosis to screen UICC stage II pancreatic ductal adenocarcinoma patients.
Comparative Study of Chemoradiation and Sequential Chemoradiation About Lung Adenocarcinoma Patients...
Lung Adenocarcinoma Patients With Postoperative in pN2The purpose of this study compares chemoradiation and sequential chemoradiation about Lung adenocarcinoma patients with postoperative in pN2 and then determines which therapeutic method is better for the patients.
Pilot Study Evaluating Broccoli Sprouts in Advanced Pancreatic Cancer [POUDER Trial]
Pancreatic Ductal AdenocarcinomaThe goal of the POUDER trial is to determine the feasibility of a randomized controlled trial regarding the application of freeze-dried broccoli sprouts rich in sulforaphane and quercetin in patients with advanced pancreatic ductal adenocarcinoma that receive palliative chemotherapy.
Spectroscopy From Duodenum
Pancreatic AdenocarcinomaPurpose of this study is to understand the clinical feasibility of duodenal spectroscopy to adenocarcinoma patients.
Staging Prostate Cancer With Hybrid C11-Choline PET/MR and mpMRI
Prostate AdenocarcinomaThe purpose of this study is to find out if a PET/MR scan in combination with standard MRI and CT scans can improve the early detection and treatment of patients with prostate cancer.
CLE for Assessment of Neoplasia After Mucosal Ablation or Resection of Gastrointestinal Neoplasia...
Barrett SyndromeBarrett's Syndrome3 moreThis study focuses on demonstrating the value of probe-based Confocal Laser Endomicroscopy (pCLE) in guiding endoscopic therapeutic procedures in Barrett's Esophagus (BE). It is a randomized controlled outcomes study including patients already treated for Barrett's Esophagus lesion(s) and undergoing high definition white light endoscopy follow up procedure, with or without pCLE (2 arms will be considered in this study). The procedures will be carried out per standards of practice with appropriately trained physicians.
XELOX+Bevacizumab Followed by Capecitabine+Bevacizumab+Radiotherapy as Neoadjuvant Treatment of...
Rectal NeoplasmsLocally Advanced Rectal AdenocarcinomaThe purpose of this study is to determine the pathological complete response rate of addition of bevacizumab to induction therapy (xelox) and concomitant treatment (capecitabine+radiotherapy), followed by surgery.
Impact of Positron Emission Tomography Imaging Prior to Liver Resection for Colorectal Adenocarcinoma...
Colorectal CancerLiver MetastasesThe purpose of this trial is to improve the management of patients with potentially surgically curable colorectal cancer liver metastases. The primary objective is to determine the impact of pre-operative positron emission tomography (PET) on patients who have been assessed as having resectable colorectal cancer liver metastases by conventional imaging (computed tomography (CT) abdomen/thorax, colonoscopy), by determining the proportion of patients who have a change in management resulting from PET.
Fluciclovine-PET/CT for Bone Metastases From Prostate Adenocarcinoma
Prostate AdenocarcinomaDetermine diagnostic accuracy of Axumin-PET positive bone lesion by confirmatory bone biopsy.