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Active clinical trials for "Adrenal Gland Diseases"

Results 1-10 of 13

Complication in Laparoscopic Renal and Adrenal Surgery (CLARAS)

Adrenal DiseaseRenal Cancer1 more

the aim of this study is clarify complication and their resolution in laparoscopic renal and adrenal surgery.

Recruiting2 enrollment criteria

Comprehensive Data Collection and Follow-Up for Patients With Thyroid, Parathyroid and Adrenal Disease...

Endocrine Disease

The goal of this data review study is to collect data to learn more about thyroid, parathyroid, and adrenal disease.

Recruiting3 enrollment criteria

Surgical Treatment of Adrenal Diseases- Laparoscopic vs. Robotic-assisted Adrenalectomy

Adrenal TumorAdrenal Disease11 more

The goal of this multicenter, observational, analytic, randomized clinical trial is to analyze the laparoscopic and robot-assisted method in the surgical treatment of patients with adrenal diseases. The main question it aims to answer are: to find the superiority of one the the surgical method mentioned above to compare the quality of life in patients with adrenal mass before surgery and after laparoscopic or robotic-assisted adrenalectomy.

Recruiting5 enrollment criteria

Efficacy and Safety of Posterior Retroperitoneoscopic Adrenalectomy: A Comparative Study

Adrenal MassAdrenal Disease2 more

This randomized comparative study assesses the safety and efficacy of the posterior retroperitoneoscopic adrenalectomy in comparison to the standard, anterior transperitoneal approach and suppose that this new technique is a safe and effective alternative to the standard approach.

Completed11 enrollment criteria

Subcutaneous Hydrocortisone Children With Congenital Adrenal Hyperplasia

Congenital Adrenal HyperplasiaHyperplasia11 more

This is an open-label, non-randomized crossover design feasibility trial comparing oral hydrocortisone treatment with interval bolus delivery (pulsatile) of subcutaneous hydrocortisone via infusion pump in children with congenital adrenal hyperplasia. Eight children, ages 4-18 yrs, will have 24-hr pharmacokinetic and pharmacodynamic profiles of cortisol, 17-hydroxyprogesterone and androstenedione concentrations while on oral hydrocortisone therapy (admission 1), during an initial trial of the subcutaneous hydrocortisone pump (admission 2), and after 6 weeks of subcutaneous hydrocortisone pump treatment (admission 3). An integrated pharmacokinetic and pharmacodynamic model will be used to determine cortisol, 17-hydroxyprogesterone and androstenedione parameters to compare the duration of time subjects have these concentrations outside acceptable ranges. Funding Source - FDA OOPD

Completed10 enrollment criteria

Prospective Phenotyping of Autonomous Aldosterone Secretion

Aldosterone DisorderAdrenal Gland Disease1 more

This prospective cohort study will investigate the physiology and progression of autonomous aldosterone secretion.

Active24 enrollment criteria

Comparison Between Posterior Retroperitoneoscopic Adrenalectomy and Laparoscopic Adrenalectomy

Adrenal Disease

The purpose of this study is to compare two surgical methods of adrenalectomy. One is called PRA(posterior retroperitoneal adrenalectomy), which is performed through 3 or 4 holes at patient's back. The other is LA(laparoscopic adrenalectomy) which is performed through patient's abdominal cavity after making 3 or 4 holes in the abdomen.

Completed18 enrollment criteria

Steroid Panel for One-step Diagnosis of Adrenal Diseases

Adrenal Disease

The aim of this study is to develop a one-step diagnostic method for adrenal diseases, Patients with adrenal diseases including non-functioning adrenal adenoma, adrenal Cushing's syndrome, primary aldosteronism, and pheochromocytoma will be recruited. Using mass spectrometry analysis based on a multisteroid panel, serum, urine, saliva, and hair samples of the patients will be analyzed. The diagnostic yield of each and combination of steroids will be evaluated.

Not yet recruiting5 enrollment criteria

Unilateral Laparoscopic Adrenalectomy for Resistant Hypertension in Patients With Adrenal Diseases...

Resistant HypertensionAdrenal Disease

ULARH is a 2-arm, prospective, open-labeled, multi-center randomized clinical trial.The purpose of this study is to compare the effectiveness of medical treatment and unilateral laparoscopic adrenalectomy for resistant hypertension in patients diagnosed with adrenal disease based on imaging tools.Relative ratio of end-point events occurence in three years is considered as primary outcome. Furthermore, we will exploit clinical factors which could indicate a favorable outcome in participants who accepted surgical treatment in this study.

Unknown status7 enrollment criteria

Lipid-poor Adrenal Masses: Evaluation With Chemical Shift MRI

Adrenal Gland Disease

The purpose of this study is to determine if certain MRI sequences can accurately diagnose adrenal masses of unknown origin.

Completed4 enrollment criteria
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