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Active clinical trials for "Macular Degeneration"

Results 1171-1180 of 1337

Anterior Corneal Striae in Hypotony

Hypotony OcularCornea Folds and Rupture of Bowman's Membrane Both Eyes1 more

The goal of this is to evaluate the biomechanical properties of hypotonous eyes with vertical anterior corneal striae and/or hypotony maculopathy compared to hypotonous eyes without striae.

Completed5 enrollment criteria

A Follow-up Physician Survey to Evaluate Physician Knowledge of Safety and Safe Use Information...

OphthalmologyMacular Degeneration

With this follow up physician survey researcher want to collect the same data from all participants of the study using a highly structured questionnaire. The questionnaire will gather information related to physician characteristics and experience with Aflibercept, as well as assess physicians' knowledge and understanding of storage and preparation, proper injection technique, and the risks associated with Aflibercept injection into the eye (intravitreal injection). Analysis will be done using descriptive statistics.

Completed4 enrollment criteria

Study Evaluating Retinal Health Monitoring System Visual Acuity Module.

Age Related Macular Degeneration

Assess the performance and usability of the RHMS Visual Acuity Module.

Completed16 enrollment criteria

The Impact of Baseline Visual Acuity on the Treatment Outcomes in Patients Treated With AflIbercept...

Wet Macular Degeneration

The study will assess the mean change in Visual Acuity (VA) (overall and stratified by baseline VA) at year 1 and 2 of treatment with Aflibercept in real-life setting. In addition, the study will ascertain the baseline VA in treatment -naïve Wet Age-Related Macular Degeneration or neo-vascular AMD (wAMD) patients who start treatment with Aflibercept in a real-life setting and it will assess the impact of baseline VA on the outcomes of Aflibercept treatment.

Completed2 enrollment criteria

Characteristics of Patients With Neovascular Age-related Macular Degeneration Enrolled in the Brolucizumab...

Age-related Macular Degeneration (AMD)

The study was a retrospective, cross-sectional, descriptive study of patients with wet AMD who enrolled in the brolucizumab Patient Support Services (PSS) program. Evidence was generated to describe their baseline demographic and clinical characteristics.

Completed3 enrollment criteria

Evaluation of Number of Patient Eyes That Remained on or Switched to Anti-VEGF Treatment After Initiation...

Age-related Macular Degeneration (AMD)

This was a retrospective cohort study to assess the treatment history, demographic characteristics, clinical characteristics, and early treatment patterns of patients who received brolucizumab for neovascular age-related macular degeneration using IRIS Registry.

Completed3 enrollment criteria

Study on Visual Function Impairments in Dry Age-related Macular Degeneration

Age Related Macular Degeneration

The study hypothesis is that patients with dry age-related macular degeneration experience visual function impairments such as defects in dark adaptation, glare intolerance, poor light transition and reading in low lighting conditions. Studies have shown that patients in the early phases of AMD with normal visual acuity commonly reported difficulty with these visual functions but there have been no systematic studies evaluating these deficits in this population. This prospective, exploratory study will include up to 130 patients with dry AMD and 60 controls. These patients will undergo the following non-invasive visual function testing: microperimetry with eye tracking low luminance visual acuity specialized color vision (cone-specific) contrast testing and night vision testing. High-resolution spectral domain optical coherence tomography (SDOCT) images will be taken of the central retina using the Spectralis OCT unit. The values of visual function tested will be correlated with the findings on SDOCT (volume/amount of drusen present in early AMD). There are no known risks to the subjects beyond what is normal for standard examinations of the eye, visual function testing and standard ocular photographic procedures.

Completed14 enrollment criteria

ERG/EOG Study in AMD Patients Treated With Ranibizumab

Age-Related Macular Degeneration

This is an open-label study assessing electrophysiologic testing of the retina with Electoretinogram (ERG) /Electrooculogram (EOG) tests in patients with exudative age-related macular degeneration (AMD). The standard FDA-approved treatment for wet AMD is ranibizumab (Lucentis). This study focuses on the ERG and EOG tests to evaluate retinal responses to ranibizumab treatment in AMD.

Completed15 enrollment criteria

Correlation Between Visual Field Defects on FORESEE HOME and on Optical Coherence Tomography in...

Age Related Macular Degeneration

The FORESEE HOME is used in the recent years to detect Age-related Macular Degeneration (AMD) lesions. The device is capable of differentiation as to stages of AMD and early detection of changes including choroidal neovascularization (CNV) The Foresee HOME demonstrates a high level of sensitivity and specificity as to the different stages of AMD including newly diagnosed or early detection of CNV. The OCT May be use as well to identify choroidal neovascularization (CNV). Comparison between the two methods will allow better understanding of both devices. The FORESEE HOME can use as an assessment tool for the progression and success of the treatment given to AMD lesions. Therefore, evaluation the size and the location of the treated lesions may serve as an additional tool.

Completed10 enrollment criteria

A Pilot Study of Functional Optical Coherence Tomography for Ocular Imaging

GlaucomaDiabetic Retinopathy3 more

Growing evidence shows that altered blood flow plays a major role in many vision-threatening diseases including glaucoma, diabetic retinopathy, age-related macular degeneration, Central Retinal Vein Occlusion, and Branch Retinal Vein Occlusion. Optical coherence tomography, an established imaging technique use for eye exam in clinical ophthalmology, provides high-resolution cross sectional images of the retina and has increased our ability to understand many eye diseases.

Completed2 enrollment criteria
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