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Active clinical trials for "Pulmonary Disease, Chronic Obstructive"

Results 531-540 of 3300

Long-term Effects of Non-invasive Ventilation in Hypercapnic Chronic Obstructive Pulmonary Disease...

Chronic Obstructive Pulmonary Disease

In this multicenter study the comparison of the mass flow distribution and redistribution versus the relative blood flow per lobe (as a surrogate for Ventilation/ Perfusion (V/Q) matching) with functional respiratory imaging (FRI) and arterial blood gas (ABG) values will be evaluated in hypercapnic Chronic Obstructive Pulmonary Disease (COPD) patients. Therefore a low dose Computed Tomography (CT) scan will be taken in a population of 30 patients with non-invasive ventilation (NIV) and in a control group of 10 patients without NIV. The CT-scan will be used for FRI.

Terminated16 enrollment criteria

Effect of Roflumilast at Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease With (Acute) Exacerbation

The purpose of this trial is to investigate if roflumilast can reduce the neutrophilic inflammation at acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD). In addition, the potential benefit of roflumilast on severity and recovery periods of acute COPD exacerbations will be assessed using patient diaries and questionnaires.

Terminated14 enrollment criteria

Effects of Non-invasive Ventilation on Rehabilitation Outcome in COPD-patients

Chronic Obstructive Pulmonary Disease

The aim of the study is to find out if nocturnal non-invasive ventilation during pulmonary rehabilitation increases exercise capacity and quality of life more than pulmonary rehabilitation alone.

Terminated10 enrollment criteria

An Open Prospective Longitudinal Pulmonary-cardiovascular Cohort Study

Chronic Obstructive Pulmonary DiseaseCardiovascular Diseases1 more

This is an observational study aiming to identify and validate biomarkers (including imaging and clinical descriptors) for chronic obstructive pulmonary disease (COPD), cardiovascular disease (CVD) and lung cancer.

Enrolling by invitation1 enrollment criteria

Interferon-alpha Treatment of Chronic Cough in Chronic Obstructive Pulmonary Disease and Idiopathic...

Pulmonary DiseaseChronic Obstructive2 more

The purpose of this study is to determine whether lozenges containing interferon-alpha can reduce the frequency and severity of coughing in patients with chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF).

Terminated17 enrollment criteria

COPD Patients Diagnosed With GERD,COPD Exacerbations After Treatment With High Dose PPI

Gastroesophageal RefluxChronic Obstructive Pulmonary Disease

The purpose of this study is to determine which COPD patients have GERD and if COPD patients with GERD treated with high dose lansoprazole for 1 year decreases the frequency of COPD exacerbations compared to the previous year without treatment.

Terminated5 enrollment criteria

Lung Deposition of TRIMBOW® pMDI in Healthy Volunteers, Asthmatic and COPD Patients

Chronic Obstructive Pulmonary DiseaseAsthma

The purpose of this study is to investigate the lung deposition and distribution pattern of TRIMBOW using a Gamma-scintigraphic technique after inhalation of a single dose of 99mTc radiolabelled TRIMBOW administered via pMDI in healthy volunteers, asthmatic and COPD patients

Terminated67 enrollment criteria

Physical Activity in Chronic Obstructive Pulmonary Disease(COPD) Acute Exacerbation Patients

COPD Exacerbation

Patients who are suffering from Chronic Obstructive Pulmonary Disease (COPD) had a decreased level of physical activity which is consequentially related to another acute exacerbation event. In this study, we selected patients from those who were admitted for acute exacerbation of COPD, evaluated physical activity by accelerometer (wearable multisensory armband devices) to find out the correlation between physical activity in COPD acute exacerbation patients.

Enrolling by invitation2 enrollment criteria

Evaluation of the Use of a Remote Monitoring and Follow-up Option for Patients With Chronic Obstructive...

Chronic Obstructive Pulmonary Disease

The purpose of this study is to evaluate the ability of the Bora Care remote monitoring solution to detect early acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD).

Not yet recruiting11 enrollment criteria

Study of Automated Care Pathway for Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary DiseaseChronic Obstructive2 more

This is a fully automated randomized trial with two randomization branch-points. The first is inclusion of disease-specific orders in the admission orders based on a predictive model using real-time data. The second is the use of dynamic orders that are end-user tested rather than static orders designed by a committee. The primary hypothesis is that automatic inclusion of disease specific orders with admission orders will improve adherence to guidelines for patients with COPD. The secondary hypothesis is that clinical and operational outcomes will improve, thereby improving value.

Terminated2 enrollment criteria
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