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Active clinical trials for "Peanut Hypersensitivity"

Results 11-20 of 126

Efficacy and Safety of QGE031 (Ligelizumab) in Patients With Peanut Allergy

AllergyPeanut

This is a 52-week, Phase 3 multi-center, randomized, double-blind and placebo-controlled study to assess the safety and clinical efficacy of two dosing regimens of ligelizumab (240 mg and 120 mg) subcutaneous injection every 4 weeks (SCq4w) in participants with a medically confirmed diagnosis of IgE-mediated peanut allergy.

Recruiting12 enrollment criteria

VE416 for Treatment of Food Allergy

Peanut Allergy

This is a single-center, randomized, double-blind trial with four arms evaluating VE416 as pretreatment or concurrent treatment in comparison to low-dose peanut oral immunotherapy (PNOIT) alone.

Recruiting19 enrollment criteria

A Safety and Efficacy Study of PVX108 in Children and Adolescents With Peanut Allergy

Peanut AllergyPeanut Hypersensitivity2 more

The overall aims of this study are to demonstrate that treatment with PVX108 immunotherapy has an acceptable safety profile and is effective for reducing clinical reactivity to peanut protein in children and adolescents with peanut allergy.

Recruiting14 enrollment criteria

Peanut Sublingual Immunotherapy (SLIT)-Tablet for Treatment of Peanut Allergy

Peanut Allergy

This clinical research study investigates the safety and tolerability of a peanut SLIT-tablet.

Recruiting15 enrollment criteria

Food-Specific and Component IgE Threshold Levels That Predict Food Allergy in People With Elevated...

Milk and/or Peanut Allergy

Background: Atopic dermatitis (AD), also called eczema, makes skin dry, red, and itchy. People with AD are more likely to get a food allergy than people without AD. But some food allergy tests are not always accurate in people with AD. Researchers want to study if people are truly allergic to milk and/or peanuts. Objectives: To improve the ways doctors test for food allergy in people with AD. Eligibility: People ages 3 21 who have had AD; have a high total IgE level (an allergic antibody); might have a milk and/or peanut allergy; and are currently enrolled in another NIH study Design: Participants will be screened under another protocol. Participants will have a physical exam, blood tests, and medical history. Participants will breathe into a plastic device that measures lung strength. Participants may get a small plastic tube inserted in their arm. Participants who have not had an allergic reaction to food in the past 3 years will do 1 or more oral food challenge (OFCs) depending on their allergies. They will eat a little bit of the food they might be allergic to. They will be watched for a reaction. If they have one, they will know for sure they are allergic. They may keep eating bigger portions of the food until they either have a reaction or finish all the food. In some OFCs, participants will get a placebo food. OFCs will last a few hours or 2 days. Participants will repeat all tests at each OFC. Participation can last up to 12 months. ...

Recruiting22 enrollment criteria

Pinpoint Trial: Prebiotics IN Peanut Oral ImmunoTherapy

Peanut Allergy

The purpose of this research is to gather information on the safety and efficacy of using a prebiotic as an adjunctive therapy to peanut oral immunotherapy. The prebiotic is not an FDA approved drug or medication rather a fiber found at local grocery stores.

Recruiting26 enrollment criteria

Follow-up of the EPITOPE Study to Evaluate Long-term Efficacy and Safety of DBV712 in Young Children...

Peanut Allergy

Open-label, follow-up study for subjects who completed the EPITOPE study.

Enrolling by invitation3 enrollment criteria

Food Oral Immunotherapy for Peanut Allergy

Peanut Allergy

This is an open label observational single center study of clinical food oral immunotherapy outcomes with biomarker samples and participant and/or caregiver-completed questionnaires in participants between 6 months and 65 years of age with IgE-mediated peanut allergy undergoing food oral immunotherapy.

Enrolling by invitation11 enrollment criteria

Longer-term Study of AR101 in Subjects Who Participated in a Prior AR101 Study (ARC008)

Peanut Allergy

The purpose of this study is to assess AR101's safety, tolerability and efficacy over an extended dosing period.

Enrolling by invitation8 enrollment criteria

Study to Assess Tolerance of Traces in Peanut/Tree Nut Allergic Children.

Food AllergyPeanut Allergy1 more

This protocol will help better define whether patients with peanut and/or tree nut food allergy can tolerate traces in products with precautionary allergen labelling.

Recruiting9 enrollment criteria
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