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Active clinical trials for "Anastomotic Leak"

Results 71-80 of 148

Transanual Tube Placement in Low Anterior Resection (LAR) for Rectal Cancer

Rectal Cancer

The purpose of this study is to evaluate the effectiveness of transanual tube placement in low anterior resection (LAR) for rectal cancer in preventing anastomotic leakage.

Unknown status10 enrollment criteria

Oral Anti-Infective Agent for Esophageal Anastomotic Leakage

Anastomotic Leakage

Anastomotic leakage is still to be a major cause of considerable morbidity and mortality after esophagectomy and gastric pull up for esophageal carcinoma. Risk factor analyses of anastomotic leakage, including blood supply, graft tension, and comorbidity, have been performed, but few studies have produced strategies that have improved operative results. This study will be performed to identify prognostic variables that might be used to develop a strategy for optimizing outcomes after esophagogastrectomy.

Unknown status4 enrollment criteria

Pancreatic Anastomosis After Duodenopancreatectomy

Pancreatic Anastomotic LeakPancreatic Neoplasms

A national, multicenter, randomized, prospective, parallel group clinical study to evaluate two therapeutic strategies (invaginating pancreatogastric anastomosis versus Blumgart anastomosis).

Unknown status7 enrollment criteria

Trial on Delay Phenomenon Utility in Preventing Anastomotic Leakage After an Esophagectomy

Esophageal Anastomotic Leak

This is a randomized clinical trial to clarify if the delay phenomenon could reduce the incidence of oesophagogastric dehiscence after an esophagectomy for esophageal cancer comparing an experimental group vs control group. The delay phenomenon will be performed by an arteriographic approach.

Completed6 enrollment criteria

Laparoscopic Anterior Resection With or Without "Dog Ear" Double-stapled Anastomosis for Rectal...

Rectal CarcinomaLaparoscopy1 more

The study evaluates the feasibility and advantage of modified laparoscopic double-staple anastomosis technique which to eliminate the 'dog ears' in laparoscopic rectal anterior resection.

Unknown status14 enrollment criteria

MRI Anastomotic Integrity of Pelvic Intestinal Anastomoses

Ulcerative ColitisIleal Pouch1 more

This protocol describes using an MRI-Enema technique to assess the integrity of colorectal anastomoses when compared to fluoroscopic water soluble contrast enema, and provides information the participant recruitment process, participant experience and study management.

Completed9 enrollment criteria

Local Metabolism of the Gastric Tube Reconstruction After Esophagectomy

MicrodialysisIschemia1 more

Postoperative surveillance of local metabolism of the surgical reconstruction after esophagectomy by means of Microdialysis. Dialysate is collected continuously for seven postoperative Days. Results analysed in a blinded fashion and related to the clinical outcome. Primary endpoint: anastomotic leakage

Completed2 enrollment criteria

Pancreaticogastrostomy Versus Pancreaticojejunostomy in Reconstruction After Cephalic Duodenopancreatectomy...

Pancreatic CancerPancreatic Anastomotic Leak

Pancreaticoduodenectomy is the standards surgical procedure for various malignant and benign disease of the pancreas and periampullariy region. During the recent years, mortality rate of pancreaticoduodenectomy has decreased to 5% in specialized centers. Although, this procedure still carries considerable morbidity up to 40%, depending of definition of complications. Pancreatic fistula remains a common complication and the main cause of other morbidities and mortality. Pancreaticojejunal (PJ) anastomosis is the most often used method of reconstruction after pancreaticoduodenectomy. Several technique modifications such as placement of the stents, reinforcement of anasomosis with fibrin glue, pancreatic duct occlusion and pancreaticogastrostomy (PG) type of anastomosis was used in order to decrease pancreatic fistula rate. Since, some retrospective studies showed better results with some technique, several meta-analyses did not show any advantage of those various modifications. It was shown that the higher risk of pancreatic fistula was noticed in patients with soft residual pancreas and small diameter of pancreatic duct. There is only one randomized study in the literature dealing with this problem. This study did not reveal any significant differences between PG and PJ in patients with soft pancreas and small duct. In order to investigate once more this important issue, the researchers conducted randomized multicenter controlled trial.

Unknown status7 enrollment criteria

Bowel Prep vs Non-Bowel Prep for Laparoscopic Colorectal Surgery

Anastomotic LeakSurgical Site Infection

Research Question: Are anastomotic leak and surgical site infection rates equivalent in patients having laparoscopic bowel resections without bowel preparation vs those having bowel preparation? Bowel preparation is a distressing and uncomfortable procedure for patients undergoing laparoscopic colorectal surgery, and also carries some risk of morbidity due to dehydration, electrolyte inbalance and possible infectious complications. If it is found that there is no difference between those patients who have preoperative bowel preps and those who do not have them, then we can save these patients this additional distress and risk at the time of their surgery.

Unknown status9 enrollment criteria

The Optimal Width of Gastric Conduit for Minimally Invasive Esophagectomy: Wide or Narrow?

Anastomotic Leakage

The study hypothesized that a narrow gastric conduit(less than 3cm in width) would minimize anastomotic leakage following minimally invasive esophagectomy. Therefore we raise this random-controlled research, and investigate the leakage ratio from different widths of gastric conduit formed during the operation.

Unknown status4 enrollment criteria
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