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Active clinical trials for "Anastomotic Leak"

Results 121-130 of 148

Bile Leaks After Biliary Surgery

Bile LeakAnastomotic Leak Biliary1 more

The objective of our study is to identify the factors influencing the occurrence of a biliary leak after performing surgery leading to the creation of a biliary anastomosis to any segment of the digestive tract.

Unknown status5 enrollment criteria

Incidence of Acute Urine Retention: Randomized Clinical Trial Comparing Early, Mid or Late Urinary...

Rectal CancerRetention4 more

DESIGN: Randomized, open-label and parallel clinical trial, assigned to early, mid, or late withdrawal of urinary catheter with a 1: 1: 1 allocation ratio. POPULATION: Patients undergoing anterior rectal resection, low rectal resection, or abdominoperineal amputation for any reason. OBJECTIVES: The main objective is to compare the incidence of acute urine retention after removal of the urinary catheter in the postoperative period of rectal resection. Secondary objectives are: Incidence of urinary tract infection after urinary catheter removal. Incidence of specific postoperative complications (Surgical wound infection, Respiratory infection, Anastomotic dehiscence, ileus). Incidence of postoperative complications assessed according to the Comprehensive Complication Index (CCI) scale. DESCRIPTION OF THE INTERVENTION: In all patients, a Rectal Resection (anterior rectal resection, posterior pelvic exenteration or abdominoperineal amputation) will be performed. In group 1A, the urinary catheter will be removed on the 1st postoperative day. In group 1B patients, the urinary catheter will be removed on the 3rd postoperative day. In group 1C patients, the urinary catheter will be removed on the 5th postoperative day. All patients will have a urine culture taken at the time of withdrawal.

Unknown status16 enrollment criteria

Human Albumin and Anastomotic Leakage After Gastric Cancer Surgery

Gastric CancerAnastomotic Leak

We investigate whether the intravenously administered human albumin is beneficial to prevent anastomotic leakage after gastric cancer surgery.

Completed3 enrollment criteria

Predictors of Intestinal Anastomosis Leakage, Application of New Predictors and New Scores

Anastomotic Leak

Aim of the work This study aims at; Early detection of disruption and leakage of intestinal anastomotic sites whether small or large intestine by using biochemical markers as predictors and indicators of leakage with application of scoring scale to assess presence or absence of leakage.

Unknown status4 enrollment criteria

Indocyanine Green Test in Bariatric Surgery

ObesityMorbid3 more

Indocyanine green (ICG) can be injected into the human bloodstream and it allows us to show stomach vascularity in real time

Completed2 enrollment criteria

The Diagnostic Dilemma of Anastomotic Leak in Esophagogastric Surgery

Anastomotic Leak

To study the diagnostic specificity and sensitivity of various modalities used for the assessment of anastomotic leak in esophagogastric surgery and to identify the most sensitive technique. Secondarily, to propose a clinical algorithm to guide clinicians in the diagnosis of anastomotic leaks esophagogastric surgeries.

Completed9 enrollment criteria

Microbiota Implementation to Reduce Anastomotic Colorectal Leaks (MIRACLe)

Colorectal CancerSurgery3 more

Aim of this study is to implement the intestinal microbiota by perioperative administration of probiotics, oral antibiotics and low volume mechanical preparation in order to reduce the incidence of colorectal anastomotic leaks and dehiscences.

Completed13 enrollment criteria

Drainage Fluid Biomarkers and Anastomotic Leakage in Colorectal Surgery. A Monocentric Prospective...

Anastomotic Leakage

Anastomotic leakage (AL) is one of the most feared intra-abdominal septic complications (IASC) after colorectal surgery. It is defined as the leak of intestinal content due to an anastomotic dehiscence. Incidence ranges from 2% to 20%. AL is usually associated to systemic inflammatory response, even if in some cases the presentation may be subclinical. Therefore, AL is suspected in patients with a strong inflammatory response and can be confirmed by imaging with contrast enhanced computed tomography (CT) scan or water-soluble contrast studies. Nevertheless, imaging has varying sensitivity and specificity and is usually performed once the patient has a clinical evidence, thus potentially delaying the correct timing for surgery. Despite several studies about this topic and the plenty of known risk factors as mentioned above, AL is still not easy to predict. Different tools other than imaging have been studied in order to make diagnosis of AL at an early stage, as the measurement of some biomarkers of inflammation in serum and in drainage fluid. Biomarkers as white cell blood count (WBC), C-reactive protein (CRP), cytokines (e.g. TNFa, IL-6, IL-1b), markers of ischemia (e.g. lactate) and procalcitonin (PCT) have been used for an early detection of AL and other intra-abdominal septic complications. The primary aim of our study was to assess the role of drainage fluid CRP and lactate-dehydrogenase (LDH) in the early detection of anastomotic leakage.

Completed6 enrollment criteria

The Role of Transanal Tube Drainage as A Mean of Prevention of Anastomotic Leakage Anastomotic Leakage...

Rectal CancerRectal Neoplasms1 more

Anastomotic leakage (AL) is considered the commonest major complication after surgery for rectal cancer. Transanal tube drainage role in the prevention of AL is still debatable.

Unknown status2 enrollment criteria

Pathophysiology of Perioperative Fluid Management in Emergency Laparotomy

Intestinal ObstructionIntestinal Perforation3 more

Pathophysiology of perioperative fluid management in patients undergoing emergency laparotomy.

Completed14 enrollment criteria
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