Intravenous Iron: Measuring Response in Anemic Surgical Patients
Colorectal NeoplasmAnemia20 Patients will be recruited with confirmed colorectal adenocarcinoma and anemia who are planned to undergo surgery. All patients will be treated with a single dose of 1g intravenous ferric carboxymaltose (FERINJECT). It is hypothesized that intravenous iron supplementation is efficacious at raising haemoglobin levels and reduced blood transfusion requirements.
Long Term Extension Study for the Maintenance Treatment of Anemia Associated With Chronic Kidney...
AnemiaRenal Insufficiency1 moreEvaluate efficacy and safety up to 36 months of titrated dose treatment with BAY85-3934 versus epoetin alfa/beta. Titration will be based on the subject's hemoglobin (Hb) response and tolerability of the prior dose. Planned doses include 15, 25, 50, 75, 100,and 150 mg once daily.
Study of the Effect of Synchronised Anaemia Management in Chronic Kidney Disease
Kidney FailureChronic1 moreAims: To establish an electronic process for CKD anaemia management using monthly synchronized dosing of erythrocyte stimulating agents (ESA). To compare this electronic process with "present anaemia management" in the traditional outpatient setting. To monitor Hb targets and clinical endpoints of study groups to model a larger multicentre study focusing on these endpoints.
Bortezomib to Treat Significant Complication of HSCT
Allogeneic Stem Cell TransplantationRefractory Autoimmune Cytopenia(s)The purpose of this trial is to study the safety and effectiveness of a drug called Bortezomib for the treatment of low blood cell counts after bone marrow transplant.
Gum Arabic as Fetal Hemoglobin Agent in Sickle Cell Anemia
Sickle Cell AnemiaThe purpose of this study is to determine whether Gum Arabic is effective as fetal hemoglobin inducing agent for sickle cell anemia patients.
A Study of Intermittent Oral Dosing of ASP1517 in Erythropoieses Stimulating Agent (ESA)-Naive Hemodialysis...
ESA-naive Hemodialysis Chronic Kidney Disease Patients With AnemiaThe objective of this study is to evaluate the safety and efficacy of ASP1517 in ESA-naive hemodialysis chronic kidney disease patients with anemia.
A Study of Intermittent Oral Dosing of ASP1517 in Peritoneal Dialysis Chronic Kidney Disease Patients...
Peritoneal Dialysis Chronic Kidney Disease Patients With AnemiaThe objective of this study is to evaluate the safety and efficacy of ASP1517 in peritoneal dialysis chronic kidney disease patients with anemia.
Treatment Response of Injectafer vs Oral Iron to Baseline Hepcidin Levels in Patients With Iron...
Iron Deficiency Anemia Secondary to IBD or Gastric BypassThe primary objective of this study is to evaluate the treatment response of Injectafer vs. oral iron to baseline hepcidin levels to determine if any of these select IBD or Gastric Bypass patients may demonstrate to be inappropriate for oral iron therapy.
IDA-01 A Randomised, Open-Label, Comparative Study of Intravenous Iron Isomaltoside 1000 (Monofer®)...
Iron Deficiency AnaemiaThe purpose of the trial is to evaluate and compare the effect of iron isomaltoside 1000 to iron sucrose in its ability to increase haemoglobin (Hb) in subjects with IDA when oral iron preparations are ineffective or cannot be used or where there is a clinical need to deliver iron rapidly.
Safety and Efficacy Study of BCD-066 Compared to Aranesp® for Anemia Treatment in Chronic Kidney...
Chronic Kidney DiseaseEnd Stage Renal Failure on Dialysis1 moreThe purpose of the study is to prove equivalence of efficacy and safety of BCD-066 and Aranesp® in treatment of anemia in end-stage chronic kidney disease patients on dialysis.