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Active clinical trials for "Aneurysm"

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Intraoperative Assessment of Pulsatile Aneurysm Wall Motion During Endovascular Aneurysm Repair...

Abdominal Aortic AneurysmEndovascular Abdominal Aortic Aneurysm Repair1 more

Endovascular abdominal aortic aneurysm repair (EVAR) aims to reduce the risk of aneurysm (AAA) rupture by reducing the blood pressure transmitted to the wall of the aneurysm. Aneurysms that remain pressurized despite EVAR may continue to grow, therefore requiring additional surgical interventions. The purpose of this study is to infer the reduction of pressure transmitted to the aneurysm wall by using intraoperative ultrasound ('M-Mode') to assess the pulsatility of the aneurysm wall. The hypothesis is that intraoperative reduction in aneurysm wall pulsatility after EVAR will correlate with improved aneurysm sac size reduction.

Unknown status7 enrollment criteria

Open Bifurcation Surgery Study

Infrarenal Aortic Aneurysm

Different cross clamping techniques in aortic surgery causes different cardiac stress

Unknown status2 enrollment criteria

Associations Between Diabetes, Arterial Stiffness and Fibulin-1 in Patients Undergoing Heart- and...

Coronary Artery DiseaseArteriosclerosis4 more

Diabetes Mellitus (DM) is frequently appearing in patients with cardiovascular disease and these patients, as a consequence herby, has a lesser prognosis. DM is often related to increased arterial stiffness and hypertension. The investigators thesis is that DM and pre-diabetes is prevalent in patients undergoing cardiovascular surgery and to some extend is under-diagnosed. At the same time the investigators imagine that DM is closely related to the degree of arterial stiffness, and that these parameters are closely related to a new biochemical marker, fibulin-1. The investigators aim to describe the prevalence of type 2 DM and dysmetabolism in patients admitted to the hospital to undergo cardiovascular surgery and besides that to investigate if there is a connection between the degree of the dysmetabolism and arterial disease, by studying arterial stiffness and by measuring a new biochemical marker, fibulin-1, which the investigators newly have identified. The results of this project will give us a measure for the quantity of unknown DM in patients undergoing cardiovascular surgery and furthermore tell us more in terms of the connections between a newly identified plasma arterial marker, arterial stiffness and diabetes.

Unknown status3 enrollment criteria

Risk Factors for Aneurysm Rebleeding

Subarachnoid HemorrhageAneurysmal

The purpose of this study is to examine the risk factors for aneurysm rebleeding.

Unknown status11 enrollment criteria

Physical,Histological,and Genetic Analyses of Lipid-rich Atherosclerotic Plaques

AtherosclerosisAortic Aneurysm1 more

Lipid-rich atherosclerotic plaques, or "vulnerable plaques" are prone to rupture, causing local intravascular thrombosis, with subsequent grave clinical consequences. Atherosclerotic plaques normally removed during surgery, and peripheral blood samples will be studied to achieve the following objectives: "1" Define histological features of the vulnerable plaque, analyze its physical characteristics, and investigate selected gene expression. "2" Study biomarkers of inflammation in conjunction with the presence of vulnerable plaques. "3" Explore the potential role of infection in atherogenesis.

Unknown status4 enrollment criteria

Biomarkers of Aneurysm Wall Strength

Abdominal Aortic Aneurysm

The purpose of this study is to identify possible in vivo biochemical and biological markers related to aortic wall strength.

Unknown status3 enrollment criteria

Evaluation of Postoperative Cognitive Function, Anxiety, Depression and Quality of Life in Patients...

Intracranial Aneurysm

This prospective single-center cohort study aims to identify the incidence of cognitive dysfunction after unruptured aneurysm operation and explore the influencing factors. The primary end point is the cognitive dysfunction at 6 months after operation.The features of cognitive function, mental status, neurological function recovery, and quality of life of patients with unruptured intracranial aneurysms at different time points would be analyzed.

Unknown status10 enrollment criteria

A Registry Study on Genetics and Biomarkers of Thoracic Aortic Aneurysm/Dissection

Aortic AneurysmThoracic2 more

This is a national registry study to determine genetic risk factor and serial biomarkers of thoracic aortic aneurysm/dissection

Unknown status20 enrollment criteria

Prospective Observation for Serial Changes of Acute Intracranial Artery Dissection Using High Resolution...

Cerebral Arterial DiseasesDissecting Aneurysm of Cerebral Artery1 more

Intracranial artery disease has been more detected with development of HR-MR. HR-MR can depict vascular wall directly and give us more information beyond the pre-existing imaging modalities such as digital subtraction angiography, magnetic resonance angiography, computed tomography angiography. Hence, HR-MR is considered to become promising imaging modality for intracranial artery disease and many studies have been published recently. However, there was not enough to differentiate various intracranial artery disease such as atherosclerosis, dissection, moyamoya disease, vasculitis, reversible vasoconstriction syndrome. In real clinical arena, intracranial artery disease is too difficult to diagnose and distinguish among the disease. Of the disease, usefulness of HR-MR has been consistently published in the detection and diagnosis of intracranial artery dissection recently. HR-MR seems to be the most important and reliable imaging method in intracranial artery dissection as of now. Therefore, intracranial artery dissection is necessary to study using HR-MR. Intracranial artery dissection is dynamic vascular pathology. The geometric change is the most common among intracranial artery disease. However, there was no report about the geometric change in HR-MR. The investigators acquired retrospective data about the natural course of intracranial artery dissection in HR-MR and are preparing for publishing an article. However, the data is not prospective and not intraindividual comparison. Therefore, reliability is not enough to convince the natural course. If the investigators got prospective and intraindividual data, definite natural course of intracranial artery dissection could be acquired and would be helpful to diagnose the dissection and differentiate from other vascular pathologies. The prospective longitudinal information from this study could guide us as the important map on the confusing HR-MR findings. The protocols for imaging are as follows: initial (optional), 1 month, 3 month, 6 month (optional), 12 month.

Unknown status7 enrollment criteria

Dynamic Contrast-Enhanced Magnetic Resonance Imaging Analysis for Prognosis of Intracranial Dissecting...

Dissecting Aneurysm of Cerebral Artery

This study will evaluate the feasibility to predict the prognosis of IDA with IMH by DCE-MRI and provide theoretical basis for the prognosis and intervention of the disease.

Unknown status2 enrollment criteria
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