Clinical Evaluation of the FluidVision Accommodating Intraocular Lens (AIOL)
AphakiaThe purpose of this study is to evaluate the safety and effectiveness of an investigational IOL.
Evaluation of the FluidVision Accommodating Intraocular Lens (AIOL) With an Improved Injector System...
AphakiaThe purpose of this study is to evaluate the clinical outcomes of an investigational IOL in patients undergoing cataract extraction and intraocular lens implantation using an improved injector system.
Evaluating Safety and Efficacy of a Modified Technique of Scleral Fixation Intraocular Lens Implantation...
AphakiaCataractCataract is the leading cause of blindness globally and cataract surgery with the implantation of intraocular lens (IOL) is the most commonly performed operation worldwide. After removal of the cataract, an IOL is usually implanted within the capsular bag. However, endocapsular implantation of IOL is not always feasible due to inadequate zonular or capsular support, intraoperative posterior capsule rupture, or in primary intracapsular cataract extraction. Predisposing factors including prior ocular trauma, intravitreal injection or intraocular surgery, co-existing ocular comorbidities like chronic uveitis, pseudoexfoliation syndrome, may increase the risk of failure of in-the-bag implantation. In such situation, the surgeons may consider implanting the IOL in the anterior chamber, ciliary sulcus, or using fixation techniques. In Asian eyes, the anterior chambers are often shallow and placement in anterior chamber may accelerate corneal endothelial cell loss leading to corneal decompensation, or worsen pre-existing glaucoma. Placement in the ciliary sulcus depends on the amount and integrity of the capsular remnant, and inadequate support may result in dislocation of the IOL. In recent years, newer forms of scleral fixation of IOL using glue or glue-less approach, although these procedure appeared to be simpler, the long-term stability of these IOL have not been evaluated against conventional approach with suture fixation. The main limitations of suture fixation technique are related to the sutures either intraoperatively (e.g. entanglement, failure to rotate and bury the suture knot) or postoperatively (breakage, dissolution of suture with time), and the learning curve required for surgeons in training. Our study aims to study the efficacy and safety of a modified technique of scleral fixation of an intraocular lens in the posterior chamber.
Accuracy of Holladay 2 Formula in the Absence of Lens Thickness
CataractsHypothesis: Holladay 2 formula is still accurate even used without lens thickness data.
Exploratory Clinical Study for Techniques Associated With the Fluid Accommodating IOL
AphakiaPresbyopiaThe purpose of this clinical study is to assess the repeatability of objective refraction using auto refraction on subjects bilaterally implanted (implanted in both eyes) with the Fluid Accommodating IOL (FAIOL).
Comparative Study of the Optical Biometer for Measurements of the Eye
Normal Non-fluencyCataract2 moreThe primary purpose of this comparative clinical study is to collect clinical data to demonstrate the equivalence of the investigational device to the predicate device for measurements of the eye. The secondary purpose is to evaluate any adverse events that occur during the clinical study.
Intraocular Position of Secondary Iris-Fixated IOLs in Aphakic Eyes
AphakiaThe purpose of this study is to evaluate the intraocular stability and safety of secondary iris-fixated IOLs in aphakic patients.
A Multi Focal Visual Outcome Study Using Different Near Additions
CataractAphakiaA multi-centre non-randomized clinical investigation to assess multifocal visual outcomes using different near additions, for the treatment of aphakia after cataract removal.
Clinical Evaluation of the Lenstec Softec HP1 Intraocular Lens
AphakiaThe study is designed as a post market evaluation of the Softec HP1 IOL for continuance of the CE certificate. The primary effectiveness endpoint is to evaluate the safety and performance levels produced by this IOL in patients requiring standard cataract surgery. There will be no change from standard procedure, other than 1 extra post op evaluation.
Clareon IOL Retrospective Data Collection
AphakiaAstigmatismThe purpose of this study is to provide real world evidence (RWE) on the performance of the Clareon ultraviolet absorbing (UVA) intraocular lenses (IOLs) to support the overall body of evidence on the Clareon IOL family.