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Active clinical trials for "Respiratory Distress Syndrome"

Results 1041-1050 of 1388

A Comparison of Optimal PEEP Determination Guided by EIT and G5 Device in Moderate and Severe ARDS...

Acute Respiratory Distress Syndrome

To Select the Optimal Positive End-expiratory Pressure in Moderate and Severe Acute Respiratory Distress Syndrome Patients by Using: the novel Non-invasive Electrical Impedance Tomography Guided Method the Protective ventilation tool G5(MV)

Completed9 enrollment criteria

Provider Perceptions of Neuromuscular Blockade in ARDS

Neuromuscular BlockadeAcute Respiratory Distress Syndrome

The proposed study will use qualitative methodology to understand health care provider perceptions of neuromuscular blockade (NMB) in patients with Acute Respiratory Distress Syndrome (ARDS). To achieve this goal the investigators will conduct a prospective ancillary study at four clinical centers participating in the NHLBI PETAL network as part of the ROSE (Reevaluation of Systemic Early Neuromuscular Blockade) clinical trial (NCT02509078). Using thematic content analysis of semistructured interviews with health care providers caring for patients enrolled in the ROSE trial the investigators will determine the barriers to NMB use and develop a framework for future NMB adoption in ARDS.

Completed2 enrollment criteria

Clinical RD (Respiratory Distress) Score for Objective Decision Making for Surfactant Therapy

Respiratory Distress Syndrome in Premature InfantSurfactant1 more

To develop a comprehensive 'Clinical RD score' for decision making for administration of Surfactant in respiratory distress syndrome in preterm infants with gestation of 26 0/7 - 34 6/7 weeks and to assess the validity of this 'clinical RD score' on a different subgroup of patients with similar gestational age.

Completed7 enrollment criteria

Video Laryngoscopy in Newborn Babies V1

Respiratory Distress Syndrome

Our research questions are Will the use of a video laryngoscope lead to decreased attempts Does this result in more successful intubations and greater confidence in the supervisor and the team that a successful intubation has been performed.

Completed3 enrollment criteria

A Comparison of Methods of Discontinuing Nasal CPAP in Premature Infants <30 Weeks Gestation

Apnea of PrematurityRespiratory Distress Syndrome

The purpose of this study is to determine if among infants <30 weeks gestational age on nasal continuous positive airway pressure (NCPAP), whether discontinuing CPAP after gradual reduction in continuous positive airway pressure (CPAP) pressure leads to successful weaning off CPAP when compared to discontinuing CPAP without weaning pressure.

Completed5 enrollment criteria

Continuous Regional Analysis Device for Neonate Lung

Infant Respiratory Distress SyndromeAcute Bronchiolitis1 more

The purpose of the study is to assess whether Electrical Impedance Tomography (EIT) has the potential to optimize the ventilator therapy, validate the effectiveness, efficacy and safety of nursing and medical interventions (endotracheal suctioning, posture changes, surfactant therapy, recruitment manoeuvres, etc.) and for early recognition of complications like pneumothorax and endotracheal tube misplacement. The study design is purely observational.

Completed10 enrollment criteria

Breathing Variability and NAVA in Neonates

Neonatal Respiratory Distress SyndromePrematurity

The current study is a crossover trial, aiming at evaluating the effect of NAVA -NIV compared to Nasal Intermittent Positive Pressure Ventilation (PC-NIV) at the same level of peak inspiratory pressure, in terms of: breath-by-breath variability of tidal breathing amplitude, variability of the other breathing patterns; lung mechanics; gas exchange; rate of episodes of apnea; bradycardia and desaturations; respiratory asynchrony and comfort, in preterm infants < 37+0 weeks+days post-menstrual age.

Completed9 enrollment criteria

Corticosteroid Treatment for Acute Respiratory Distress Syndrome

Acute Respiratory Distress Syndrome

It is acknowledged that IL-18, as a product of the inflammasome, is involved in host defence against viral and bacterial stimuli by modulating the immune response. The aim of this study was to determine IL-18 levels in serum of patients with acute respiratory distress syndrome and to investigate whether corticosteroid attenuate its levels. In addition, to explore the effect of corticosteroid therapy on the prognosis of ARDS.

Completed10 enrollment criteria

Effective Approaches & Strategies to Ease Off Nasal CPAP In Preterm Infants

Neonatal Respiratory Distress SyndromeExtremely Low Birth Weight Infant (ELBW)1 more

Though Nasal Continuous Positive Airway Pressure (NCPAP) is a commonly used form of non-invasive neonatal respiratory support, the optimal method of weaning off NCPAP is not well established. In this prospective, two-center randomized control trial we hypothesize that gradually increasing time off NCPAP (sprinting) increases the success of weaning NCPAP off in infants born between 23 0/7-30 6/7 weeks of gestational age.

Completed19 enrollment criteria

Asynchrony During Mechanical Ventilation in Patients With Acute Respiratory Distress Syndrome

Respiratory Distress SyndromeAdult1 more

Asynchrony during mechanical ventilation has been poorly described in patients suffering from acute respiratory distress syndrome. The purpose of this study is to describe the frequency of asynchronies (ineffective efforts and double triggering) in these group and evaluate potential risk factors and prognosis implications.

Completed4 enrollment criteria
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