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Active clinical trials for "Arthritis"

Results 541-550 of 3640

Biobank for Inflammatory Chronic Diseases and Osteoporosis

Rheumatoid ArthritisPsoriatic Arthritis2 more

The aim of this study is to constitute a biobank for patients followed in the Rheumatology center of Toulouse University Hospital for a chronic inflammatory rheumatism including rheumatoid arthritis (RA), spondyloarthritis(SpA), and psoriatic arthritis (PsA) or a chronic bone disease including osteoporosis in order to identify biomarkers associated with therapeutic response.

Recruiting7 enrollment criteria

Exploratory Study of Ultrasound Signs of Native Septic Arthritis of the Knee

Ultrasound Therapy; ComplicationsSeptic Arthritis1 more

Primary objective: Description of ultrasound abnormalities seen in native septic arthritis of the knee during each visit. Primary endpoint: Describe the ultrasound abnormalities observed on Day 0, Day 10, 6 weeks, 3 months, 6 months, during native septic arthritis of the knee.

Recruiting9 enrollment criteria

QIST Collaborative - Arthroplasty Research Cohort (ARC) Study

Hip ArthritisKnee Arthritis

The ARC Study is a national observational cohort study to investigate patient reported and clinical outcomes after hip and knee replacements. The study has the following objectives: To evaluate outcomes following hip and knee replacements. To determine risk factors for adverse outcomes in primary hip and knee replacements. To identify targets for future research and intervention in patients undergoing primary hip and knee replacements To provide a resource from which to identify potential participants for future clinical trials, and to use data collected in the ARC Study as comparison or control data for trial participants who have been randomised to receive one or more interventions. Participants are recruited and consented online. Patients are invited to participate by collaborating surgical teams nationally in outpatient clinics at the time of being added to a waiting list, in addition to an advertising campaign to recruit patients. They are directed to an online portal where they will be able to review further information. Consent and data collection is completed electronically through patients entering data online. Baseline demographics and characteristics are recorded, including details of socio-demographics, lifestyle, health status and patient reported outcome measures (PROMs). Patients then undergo hip/knee replacement and postoperative rehabilitation according to the standard care and protocols of the hospital and the preferences of their treating surgeon. Follow-up data, including PROMs, is collected via online questionnaires up to two years following surgery. The study will ultimately also enable multiple trials to be embedded within the cohort study, using a 'Trials within Cohorts' (TwiCs) methodology.

Recruiting7 enrollment criteria

The Study of Koebner in Patients With Psoriasis and Psoriatic Arthritis

PsoriasisPsoriasis; Arthritis (Etiology)1 more

PSODEEP 1 is a descriptive digital interview study where we intend to include at least 900 individuals. Individuals with known psoriasis or known psoriatic arthritis will access the digital interview via a QR code distributed via their rheumatology or dermatology department using their smartphones. Data on answers results are stored digitally and can be accessed parallel to recruitment. Questions focus on following fields (all self reported): background information (age/sex), disease duration, disease course/fluctuation, disease diagnosis as given by MD, disease treatment, disease severity, disease classification, disease triggers, screening of psoriatic arthritis (questions derived from PEST questionnaire), Koebner occurence, variability in Koebner over time, deep-Koebner occurence and variability in Deep-Koebner over time.

Recruiting6 enrollment criteria

Complex Molecular Etiology and Cellular Landscape of Hip Osteoarthritis

OsteoarthritisHip1 more

The purpose of this study is to cast light on the highly complex etiology and cellular landscape of hip osteoarthritis by utilising single-cell and spatial transcriptomics.

Recruiting9 enrollment criteria

Early Rheumatoid Arthritis Lung Disease Study

Rheumatoid Arthritis

The primary goal of this study is to investigate lung disease, through pulmonary function and high resolution chest CT, in newly diagnosed RA patients. Extra-articular disease occurs in approximately 50% of RA patients, with the lung being a common site of involvement. Investigators goal is to understand the prevalence of lung disease in early RA patients and to better characterize it through questionnaires, imaging, and serum studies. Additionally, the goal is to find novel biomarkers to predict lung disease in RA patients.

Recruiting4 enrollment criteria

Comprehensive Nano - Post Market Clinical Follow-Up Study

OsteoarthritisAvascular Necrosis3 more

This data collection project is intended to provide clinical outcomes data to engineering, marketing as well as fulfill the post market surveillance requirements of various regulatory authorities. The study will be a prospective and one-arm.

Recruiting9 enrollment criteria

Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies

Chronic Obstructive Pulmonary Disease (COPD)Smoking4 more

The purpose of this study is to obtain biologic materials from the blood, airways and/or urine of normal individuals and individuals with lung disease. The normal are used to establish a set of normal ranges for various parameters. These provide control information when compared to individuals with various pulmonary diseases, and will help in understanding of the etiology and pathogenesis of various lung diseases. The underlying hypothesis is that the pathologic morphological changes in the airway epithelium must be preceded by changes in the gene expression pattern of the airway epithelium and potentially in macrophages.

Recruiting35 enrollment criteria

Validation of the French Version of the CQR (Compliance Questionnaire Rheumatology)

Rheumatoid Polyarthritis

The purpose of this study is to develop a French language version of the Compliance-Questionnaire-Rheumatology for use in French and Francophone rheumatology services

Recruiting9 enrollment criteria

10-year Follow-up of Patients With Rheumatoid Arthritis Who Received Structured Treat-to-target...

Rheumatoid Arthritis

The ARCTIC-FORWARD study is a multi-center prospective observational study investigating the long-term outcomes of rheumatoid arthritis (RA) patients who received structured treat-to-target therapy early in their disease. The main hypothesis of this project is that RA treat-to-target strategies during the first two years of disease result in beneficial long-term outcomes both with regards to joint damage, disease activity and societal costs.

Recruiting0 enrollment criteria
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