Fibreoptic Intubation With and Without Sellick´s Maneuver
Intubation IntraesophagealRespiratory Aspiration of Gastric ContentsThe goal of this study is to evaluate the effect of Sellick´s Maneuver, a firm pressure on the throat, just below the Adams apple, to occlude the esophagus, in order to prevent aspiration of gastric contents, on intubation with a flexible fiberscope. The result of this study will be participate in the discussion of the importance of Sellick´s Maneuver.
An Open Label Placebo Study To Assess The Inhalation Profile Obtained By Acoustic Monitoring In...
COPDPhase IIa, single center, open-label, single-arm study, to evaluate the inspiration profile through the NEXThaler device in adult COPD patients with varying degrees of airflow limitation
Dose Titration of Propofol for Tracheal Intubation in Children With Sevoflurane Inhalation Induction...
Pediatric Urinary DisordersDose titration of propofol for tracheal intubation in children with sevoflurane inhalation induction.
The Comparison of Oxidative Stress Between Inhalation Anesthetics
Oxidative StressCardiac SurgeryOxidative stress is an unavoidable event during cardiac surgery. Isoprostanes have been demonstrated to be a reliable biomarker for the evaluation of oxidative stress in vivo.The aims of this study are(1)to develop an accurate liquid chromatography-tandem mass spectrometry methods for the detection of urinary isoprostane isomers in samples collected from healthy volunteers(for method quality control) and patients receiving a cardiac surgery (2)to investigate the change of isoprostanes after cardiopulmonary bypass(CPB) (3)to investigate the effect of different anesthetics on isoprostanes.
The Effect of a Retrofit Particle Trap on the Vascular Effects of Diesel Exhaust Inhalation
Heart DiseaseThe purpose of this study is to determine whether a retrofit particle trap can reduce the adverse vascular responses to diesel exhaust inhalation
A Study to Estimate the Time Course of PF-00241939 Concentration in the Blood Following Dosing by...
PharmacokineticsThe purpose of this study is to investigate the time course of PF-00241939 concentrations in the blood following dosing by oral inhalation using dry powder inhalers.
Comparison of Sleep Study Results After Partial Intracapsular Tonsillectomy Versus Total Tonsillectomy...
Sleep-disordered BreathingObstructive Sleep ApneaThe purpose of this study is to demonstrate similar improvements in sleep-disordered breathing as determined by sleep study with microdebrider-assisted partial intracapsular tonsillectomy and adenoidectomy versus total Bovie electrocautery tonsillectomy and adenoidectomy.
Relative Bioavailability Study to Compare Inhalation of Terbutaline Sulphate 1,5mg Via Turbuhaler...
Healthy VolunteersRelative bioavailability study to compare inhalation of Terbutaline Sulphate 1,5mg via current version of Turbuhaler with inhalation via a new version
Comparison of Tapered- vs. Cylindrical-shaped Tube Cuffs Pressure Alteration With Nitrous Oxide...
Adverse Effect of Other General AnestheticsAnesthesia Intubation Complication2 moreWhen using nitrous oxide for general anesthesia, nitrous oxide diffusion induces intracuff hyperinflation of the endotracheal tube. Furthermore the difference among various types of cuffed endotracheal tubes in cuff pressure behavior during nitrous oxide exposure. TaperGuard(TM) tube has been newly introduced and has tapered-shape cuff. In vitro study, the intracuff pressure of TaperGuard(TM) tube was lower than that of conventional tube with cylindrical-shaped cuff of the conventional tube(Hi-Lo(TM) tube). Therefore, this clinical study is needed to evaluate the intracuff pressure during general anesthesia with nitrous oxide exposure.
Sleep Disordered Breathing and Its Impact on Neuro-cognitive Performance and Quality of Life in...
Parkinson's DiseaseSleep Disordered Breathing1 moreThe purpose of this study is to determine the impact of sleep and breathing problems during sleep on memory, attention, and general well being (quality of life) in people with Parkinson Disease.