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Active clinical trials for "Atrial Flutter"

Results 71-80 of 177

Double Blind Placebo COntrolled Dose Ranging studY of the eFficacy and safEty of SSR149744c 300...

Atrial FibrillationAtrial Flutter

Double blind study to assess versus placebo the efficacy of SSR149744C for the conversion of atrial fibrillation/flutter to sinus rhythm at the time of the planned electrical cardioversion.

Completed3 enrollment criteria

Placebo Controlled Double-blind Dose Ranging Study of the Efficacy and Safety of SSR149744C 50,...

Atrial FibrillationAtrial Flutter

Double blind study to evaluate the efficacy and tolerability of SSR149744C and select a dose to be further investigated in the maintenance of sinus rhythm after electrical, pharmacological or spontaneous conversion of AF/AFL.

Completed2 enrollment criteria

Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With...

Current or Recent History of Atrial Fibrillation

This study is being done to compare the effects of bucindolol hydrochloride (bucindolol) to metoprolol succinate (Toprol-XL) on the recurrence of symptomatic atrial fibrillation/atrial flutter in patients with heart failure who have a specific genotype for the beta-1 adrenergic receptor.

Completed16 enrollment criteria

Use of Dabigatran Etexilate to Prevent Stroke and Thromboembolism

Atrial FibrillationAtrial Flutter

The purpose of this study is to evaluate major adverse bleeding risks, and thromboembolic event rates post radiofrequency (RF) ablation. The primary goal is to establish safety of dabigatran use for peri-procedural anti-coagulation after left atrial catheter radiofrequency ablation, or cryoablation procedures.

Completed17 enrollment criteria

Safety and Efficacy of Vanoxerine for Conversion of Atrial Fibrillation or Flutter to Normal Sinus...

Symptomatic Atrial FibrillationAtrial Flutter

Evaluate the safety and efficacy of a single oral dose of vanoxerine compared to placebo, in a dose modification manner, on the conversion of symptomatic atrial fibrillation (a-fib) or flutter of recent onset to normal sinus rhythm.

Completed24 enrollment criteria

Detection of Atrial Fibrillation After Cardiac Surgery

Atrial FibrillationAtrial Flutter3 more

The aim of the SEARCH-AF trial is to evaluate a novel diagnostic tool for detecting post-operative atrial fibrillation or flutter (POAF/AFL) in cardiac surgical subjects during the early, sub-acute post-operative period. The population includes cardiac surgical subjects who have either developed or are at risk for developing new onset POAF/AFL and who are at risk for stroke, as determined by their CHA2DS2-VASC (congestive heart failure, hypertension, age ≥75 years (2 points), diabetes mellitus, previous stroke/transient ischemic attack (TIA) (2 points), vascular disease, age 65-74 years, sex class (female)) score. These subjects must not have had a history of AF/AFL before cardiac surgery. The intervention group will undergo up to 30 days of continuous cardiac rhythm monitoring with an adhesive, patch-based monitor (Medtronic SEEQ™ mobile cardiac telemetry system or the CardioSTAT (Icentia Inc.) cardiac rhythm monitoring device). The control group will receive usual care, which does not involve planned cardiac rhythm testing within the first 30 days after study randomization. The primary outcome is documentation of sustained atrial fibrillation or flutter within the first 30 days after randomization. In addition, subjects in both groups will undergo 14 days of continuous cardiac rhythm monitoring with the Medtronic SEEQ™ mobile cardiac telemetry system or the CardioSTAT (Icentia Inc.) cardiac rhythm monitoring device at 6±1 months after their index cardiac surgery.

Terminated22 enrollment criteria

Comparison of Bolus Dosing of Methohexital and Propofol in Elective Direct Current Cardioversion...

Atrial FibrillationAtrial Flutter

A randomized, open-blinded, prospective study to evaluate the timeliness and safety of direct current cardioversion (DCCV) when using methohexital when compared to the more often used propofol.

Completed3 enrollment criteria

Therapy™ Cool Flex™ Irrigated Ablation System for Typical Atrial Flutter

Typical Atrial Flutter

To demonstrate that ablation with the Therapy™ Cool Flex™ Irrigated Ablation System is effective in the treatment of typical atrial flutter (cavo-tricuspid dependent) and that its use does not result in an unacceptable risk of intra-procedural, serious cardiac adverse events.

Completed18 enrollment criteria

Catheter Evaluation for Endocardial Ablation in Patients With Typical Atrial Flutter

Atrial Flutter

The primary objective is to provide additional corroborative safety and efficacy data for the Navistar Thermocool catheter for the treatment of subjects with typical atrial flutter (AFL).

Completed16 enrollment criteria

Remote Magnetic Navigation For Cavotricuspid Isthmus Ablation

Atrial Flutter

The purpose of this study is to evaluate the influence of remote magnetic catheter navigation on the safety and efficacy of mapping and radiofrequency ablation of the cavotricuspid isthmus in patients with typical atrial flutter.

Completed4 enrollment criteria
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