Active clinical trials for "Attention Deficit Disorder with Hyperactivity"

The goal of this pilot feasibility and utility study is to develop and validate a method that is reproducible over time for assessing biobehavioral and autonomic markers of impulsivity and their utility in assessing treatment outcome in preschool children with ADHD.

This study will determine the effectiveness of an intervention for preventing at-risk kindergarten and pre-kindergarten children from developing attention deficit hyperactivity disorder.

The two purposes of this study are to determine what effect the chronic and moderate/heavy drinking of alcoholic beverages has on the blood level of bupropion and chlorzoxazone and their major breakdown products in the blood and on the stimulant effect of bupropion and to determine what effect a normal and common (25% frequency) genetic variation of a specific liver enzyme (that breaks down bupropion) has on the blood levels of bupropion and its major breakdown products in the blood and on the stimulant effect of bupropion. Two groups of volunteers will be recruited for this study: volunteers who drink moderate to heavy amounts of alcohol frequently and volunteers who usually do not drink alcohol. Volunteers will NOT be asked to change their drinking (or nondrinking) habits during the study.

This study will assess the effectiveness of the "Keeping Families Strong" program (KFS) in avoiding or delaying the onset of psychiatric disorders among children with depressed mothers.

This 6-week study is to determine if the study drug, Methylphenidate Hydrochloride (HCl) Extended-Release Chewable Tablets (ERCT), is safe, tolerable and effective when compared to a sugar pill or placebo in children 4 to 5 years of age with ADHD.

Objective: The present study aimed to determine balance in children with attention deficit hyperactivity disorder compared to normal peers. Also, it investigated the correlation between their balance and the total percentile scores of ADHD Rating Scale-IV. Design: Cross sectional design. Methods: Sixty children participated in this study from both sexes (42 boys and 18 girls) with age ranged from 60 to 84 months. They were divided into two groups based on the ADHD Rating Scale-IV. Control group: 30 typically developed children from both sexes (20 boys and 10 girls) with mean age 67.53 ± 1.41 months. They had the total percentile scores of ADHD Rating Scale-IV ≤ 50. Study group: 30 children from both sexes (22 boys and 8 girls) suffering from attention deficit hyperactivity disorder (ADHD) with mean age 68.60 ± 4.62 months. They had the total percentile scores of ADHD Rating Scale-IV ≥ 93. Both groups were assessed for their balance by Pediatric Balance Scale (PBS).

The association between levels of zonulin and occludin and behavioral/emotional problems in children with ADHD are investigated.

The purpose of this study is to test clinical strategies that pediatric providers may use to prevent misuse and diversion of stimulants by their adolescent patients with ADHD.

Inattentive behaviors are a common childhood condition that presents to the general pediatrician. While some of these behaviors are expected during childhood, others need work-up to ensure optimal functioning at home and school. A number of these children ultimately go on to have a mental health conditions, such as ADHD. However, inattentive symptoms represent a broad spectrum of potential behavioral and mental health conditions, such as pediatric anxiety which can masquerade as or co-exist with ADHD. Treatment is quite different and general pediatricians must have ways to facilitate the accurate identification of children needing further work-up and referral. Health information technology can greatly improve pediatricians' ability to identify and refer children with inattentive symptoms for further work-up. This study represents initial work to revise an existing computer decision support system's module for identification of ADHD to include screening questions and prompts for anxiety.

The primary objective of the study is to evaluate the efficacy of SPD489 compared to placebo in adolescent subjects (13-17 years of age inclusive) with ADHD in the analog classroom setting based on the Permanent Product Measure of Performance (PERMP) total score assessed across 2, 4, 9, 13, 14, and 15 hours post-dose on the last day of each double-blind crossover period.