Autism, Emotional Processing, and the Amygdala
Autism Spectrum DisorderEmpathy imbalance hypothesis suggests that individuals with autism Spectrum Disorder (ASD) should have a deficit of cognitive empathy and a surfeit of emotional empathy. Considering that inconsistent amygdala reactivity to emotional faces might be ascribed to aberrant attention in ASD, the investigators hypothesized to investigate if there would be an imbalance between conscious and nonconscious emotional processing. This fMRI study recruited 26 youths and young adults with autism spectrum disorder and 25 matched controls, and measured their amygdala reactivity and functional connectivity in response to conscious and nonconscious (backward masked) perception of threatening faces. Keywords: Autism Spectrum Disorder; amygdala reactivity; emotional processing; fMRI
Somatic Diseases in Autistic Children
Autistic Spectrum DisorderSomatic DisordersFor many reasons, medical monitoring in autistic patients is very difficult. This study is designed to determine the prevalence of comorbid diseases (neurological, cardiac, digestive, dental diseases…) in patients suffering from ASD to prevent them or diagnose them earlier.
Somatic Symptoms in Autism Spectrum Disorder: Data Integration
Autism Spectrum DisorderSomatic Symptom DisorderAutistic patients have higher chances commorbid somatic symptoms. Therefore, it leads to more health-related concerns, such as autoimmune disease, gastrointestinal disease, cardiovascular disease, autonomic disorders. On average, autistic patient's life span is 16 years shorter than non-autistic patients. Furthermore, autistic patients are not able to convey or communicate their somatic symptoms in a clear and comprehensive manner. This leads to unable to receive proper health care in a timely manner.
Nutritional Status and ASD Severity of Autistic Spectrum Disorder Children in Addis Ababa, Ethiopia;...
Autistic Spectrum DisorderThe study conducts a case control analysis of the nutritional status and intake of autistic spectrum disorder diagnosed children as compared to typically developing children in Addis Ababa, Ethiopia. It included analysis of anthropometric measurements, three days food diary food intake, urinary iodine analysis, childhood autism rating scale diagnosis, food frequency and eating behavior questioner and proximate analysis of one day major meals of selected subjects.
A Non-Drug Study on the Relationship Between Exploratory Biomarkers and Functional Dimensions in...
Healthy VolunteerAutistic Disorder1 moreThis multi-center, non-drug study will explore the relationship between exploratory biomarkers and functional dimensions in male adult individuals with Autistic Disorder or Asperger's Syndrome and healthy volunteer controls. Subjects will undergo a number of assessments on study visit Day 1.
Android Mobile Devices to Assist Routine Anticipation for Autistic Children
AutismThe objective of this work is to develop an application to run on a mobile device Android tablet that features visual routines for autistic children.
Swiss Early Intervention Project in Autism: An Evaluation of Early Intervention Outcome
Autism Spectrum DisorderThis study aims to investigate the effectiveness of early (before the age of 5 years) and intensive intervention for children with Autism Spectrum Disorders.
Association Between Autism and Iron Deficiency
Autism in ChildrenAssociation between Autism and Iron Deficiency in Children Diagnosed Autism
Mycobiome Evaluation in Children With Autism & GI Symptoms
AutismGastrointenstinal SymptomsThis study's primary aim is to explore the potential differences in the gut mycobiome of children with autism spectrum disorder compared to otherwise healthy children. The secondary objective of this study is to evaluate whether the presence of specific species of fungi (e.g. Candida tropicalis, C. albicans, or Saccharomyces cerevisiae), in stool: 1) correlates with increased gastrointestinal symptoms; 2) correlates with evidence of increased behavioral problems (as assessed by the Aberrant Behavior Checklist or Social Responsiveness Scale-2); or 3) plays the same role as a constituent of commensal gut microflora as in normal controls. The scale indicates severity of social deficits in the autism spectrum as mild, moderate or severe. Additionally, the study aims to compare the fecal and oral fungi in these children because many fecal mycobiota are felt to originate in the oropharynx.
Shifting Brain Excitation-Inhibition Balance in Autism Spectrum Disorder
Autism Spectrum DisorderThis study investigates brain response to single acute dose of cannabidiol, cannabidivarin, and placebo in healthy men with and without autism spectrum disorder