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Active clinical trials for "Behcet Syndrome"

Results 61-70 of 98

Immunogenetic Mechanisms in Behcet's Disease

Behcet's DiseaseUveitis

Background: - Uveitis, the inflammation of the interior of the eye, is responsible for numerous new cases of legal blindness every year. Uveitis can be caused by Beh(SqrRoot)(Beta)et s disease (BD), a chronic inflammatory disorder that can affect the eye, mucous membranes, and other body organs such as the joints, intestinal tract, blood vessels, and central nervous system. Objectives: The purpose of this study is to see how genes affect Beh(SqrRoot)(Beta)et s disease and if there are differences in Beh(SqrRoot)(Beta)et s disease among people of different backgrounds. Eligibility: Individuals who have a diagnosis of BD and are enrolled in another NIH study. Individuals who are willing to donate blood for the purposes of this research study and who are willing to have their blood stored for possible future/other research purposes. Design: As part of the study, blood samples will be drawn from participants when an exacerbation in disease activity occurs and before and after any significant change in treatment for BD. No treatments will be provided in this study.

Terminated4 enrollment criteria

Etanercept: Single Blind Control Study in Ocular Manifestations of Behcet's Disease

Behcet SyndromeUveal Disease

The purpose of this study is to find if Etanercept can improve the outcome of ocular lesions of Behcet's Disease treated with Methotrexate and Prednisolone

Unknown status5 enrollment criteria

Flucinolone Acetonide Implant for Treating Refractory Ocular Behcet's Disease

Ocular Behcet's Disease,Non-Infectious Uveitis1 more

Objectives: To describe the safety and efficacy of intravitreal flucinolone acetonide implants in the management of patients having refractory ocular Behcet's disease Hypothesis: A descriptive observational study Study design: A 1-year, multi-center (including four Korean medical centers) observational study

Unknown status21 enrollment criteria

The Efficacy of Methylprednisolone in the Treatment of Patients With Ocular Involvement in Behcet's...

Behcet's Disease

The goal of this study is to examine the efficacy of 1gram/day intravenous pulses of methylprednisolone on 3 consecutive days in Behcet's patients with ocular involvement. A total of 34 Behcet's patients referring to Behcet's clinic in Shariati hospital whose problem was confirmed with new international criteria of Behcet's disease (ICBD) will be randomly assigned into one of the two equal groups of intervention or control. Behcet's patients are those with ocular involvement who were under the same cytotoxic treatment with cyclophosphamide and azathioprine. For the patients in the intervention group, intravenous infusion of 1000 mg methylprednisolone in 100cc D/w 5% or 100cc D/w5% on 3 consecutive days will be added to treatment diet. Then treatment will begin with oral prednisolone, 0.5 mg/kg. After that, all the patients were followed up with no other therapeutic intervention by study group. The patients will be visited every 2 months by an ophthalmologist and study group for 6 months in 3 settings. To estimate the ocular inflammation of patients, we use visual acuity, retinal and ocular posterior chamber inflammation index.

Unknown status8 enrollment criteria

Anti IL-18 (GSK1070806) in Behcet's Disease

Behcet's Disease

The primary outcome measure of the study is to demonstrate the safety and tolerability of GSK1070806 in the Behcet's disease population at 24 weeks, with biochemical and clinical efficacy and mechanistic studies to further explore the pathogenesis of Behcet's disease important secondary and exploratory outcomes.

Unknown status35 enrollment criteria

Diode Laser Versus Topical Corticosteroids in Management of Oral Ulcers in Behcet's Disease

AutoimmuneBehcet Syndrome

Laser therapy is increasingly showing promising results in dental field including oral ulcers.This trial will assess the usefulness of Diode Laser compared to corticosteroid on oral ulcers of patients diagnosed with Behcet's disease.

Unknown status11 enrollment criteria

Special Investigation in Patients With Intestinal Behcet's Disease (All Case Investigation)

Behcet's Disease

This investigation was conducted to obtain the following information regarding the use of Adalimumab (Humira®) 40mg Syringe 0.8mL for Subcutaneous Injection in patients with Intestinal Behcet's Disease. Incidence and conditions of occurrence of adverse reactions in clinical practice Factors likely to affect the safety and effectiveness

Completed7 enrollment criteria

A Prospective, Mono-Country and Multi-center Study to Observe Safety and Effectiveness of Adalimumab...

Intestinal Behcet's Disease (BD)

This study evaluates the safety profile and effectiveness of adalimumab in Korean intestinal Behcet's disease (BD) patients in routine clinical practice.

Completed6 enrollment criteria

Behçet's Disease and Eosinophil Cationic Protein

Behçet's Disease

Eosinophil cationic protein (ECP) is a matrix protein of eosinophils and has been reported to reflect eosinophil activity. Few studies have examined the role of eosinophils in the pathogenesis of Behçet's disease. The purpose of the present study is to investigate the serum ECP levels in BD and its relation to clinical activity.

Completed2 enrollment criteria

Assessment of Endocan Serum Levels in Patients With Behcet Disease

Behçet

The aim of our study was to assess serum endocan levels in patients with Behcet disease and to correlate it with various disease clinical and laboratory parameters of disease activity as well as carotid intima media thickness.

Completed9 enrollment criteria
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