Closed vs. Open Face Masks for Cranial Radiotherapy
Brain TumorBrain Metastases2 moreThe aim of the study is to evaluate whether open-face masks improve patient comfort/preference whilst maintaining immobilization performance as known for closed masks in patients undergoing whole or partial cranial radiotherapy.
Multisession Radiosurgery in Residual/Recurrent Grade II Meningiomas.
Meningioma AtypicalFractionated radiosurgery will be delivered to atypical meningioma lesions in salvage setting for patients who present post-surgical residual lesion or develop recurrence.
Vascular Endothelial Growth Factor (VEGF) Levels in Brain Tumor Patients
GliomaMeningiomaObjectives: This study is looking at the level of vascular endothelial growth factor (VEGF) circulating in the blood stream of patients diagnosed with either a meningioma or a glioma. The questions that will be addressed include: Can VEGF level alert us to tumor progression or recurrence before MRI changes occur? Is the VEGF level an indicator of the response to treatment? Does the VEGF level correlate with tumor histology and behavior? Is there a relationship between VEGF level and outcome?
Establishment and Characterization of Meningioma Patient-derived Organoids
MeningiomaIn this study, meningioma organoids will be established from patients' tissues and the characterization of the organoid will be performed.
Semi-automated Segmentation Methods of SSTR PET for Dosimetry Prediction
Refractory MeningiomaTumor dosimetry with somatostatin receptor-targeted peptide receptor radionuclide therapy (SSTR-targeted PRRT) by 177Lutetium-DOTATATE might contribute to improve follow-up and treatment response of refractory meningiomas. This study aims to evaluate Standard Uptake Value mean (SUVmean) as a tumoral absorbed dose predictive predictive factor and propose semi-automated segmentation method to determine metabolic tumor volume with pretherapeutic 68-Gallium-DOTATOC PET.
Automated Segmentation and Volumetry for Meningioma Using Deep Learning
MeningiomaArtificial IntelligenceU-Net-based architectures will be applied to 500 contrast-enhanced axial MR images of different patients from a single institution after manual segmentation of meningioma, of which 50 were used for testing. Tumor volumetry after autosegmentation by trained U-Net-based architecture is final goal.
Meningiomas and Treatment With CYPROTERONE ACETATE or Progestin
MeningiomaInvestigators observe an increase risk of meningioma in patient treated by CYPROTERONE ACETATE or other form of progestin. Investigatorsdiscribe caractéristics of meningioma and treatement of the patients follow up in CHRU of Brest
A Comparative Study of Prophylactic Anticoagulation in Meningioma Surgery
MeningiomaThe aim of the study is to compare different strategies for prevention of venous thromboembolism related to intracranial meningioma surgery. The investigators identified three hospitals where two have a very restrictive approach with respect to anticoagulant therapy while at the third hospital the use of anticoagulation the day before surgery was initiated as routine prophylaxis. Based on this "natural experiment" it will be explored whether the use of anticoagulant prophylaxis is associated with reduced risk of venous thromboembolism and/or associated with increased risk of postoperative hemorrhage as compared to the 2 cohorts where this intervention were absent.
Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System Germ Cell Tumor19 moreThe purpose of this study is to collect and store brain tissue samples and blood from children with brain cancer that will be tested in the laboratory. Collecting and storing samples of tumor tissue and blood from patients to test in the laboratory may help the study of cancer in the future.
Multisession Radiosurgery in Large Meningiomas
Intracranial MeningiomaThis is a prospective observational trial consisting of robotic multisession radiosurgery (CyberKnife ®) for large and medium size and/or located at critical site benign intracranial meningiomas.