Xisomab 3G3 for the Prevention of Catheter-Associated Thrombosis in Patients With Cancer Receiving...
LymphomaMalignant Solid Neoplasm1 moreThis phase II trial studies how well xisomab 3G3 works in preventing catheter-associated blood clots (thrombosis) in patients with cancer receiving chemotherapy. Many patients with cancer develop blood clots from their catheters and can have pain, swelling, and other symptoms. They also often require blood thinners, which can increase the risk of bleeding. Xisomab 3G3 is type of drug called a monoclonal antibody that may prevent blood clots caused by a catheter in patients receiving chemotherapy.
Comparison of the Effects of Lower Limb Immobilisation With Cast and Orthosis
Venous StasisDeep Venous ThrombosisIn this study we are going to measure the blood flow in the lower limbs under cast immobilisation and also under mobilisation with an orthosis. The aim is to evaluate how the aforementioned modalities affect the blood flow and also to compare between the two.
The Effects of Dietary Erythritol on Platelet Reactivity and Vascular Inflammation
Platelet AggregationSpontaneous1 moreThe purpose is to conduct a dietary intervention study in which human participants will consume beverages sweetened with erythritol or aspartame, each for 2 weeks, in a randomized crossover design
NAUTILUS CE-mark Trial of the FLOWer Cerebral Embolic Protection Device
Aortic Valve StenosisIntracranial Embolism and ThrombosisThe purpose of this clinical study is to assess the safety, performance, and treatment effect of the use of the AorticLab FLOWer System, in preventing cerebral thromboembolic complications in patients with indication for a TAVI (Transcatheter Aortic Valve Implant).
Reduced Anticoagulation Targets in ECLS (RATE)
Heart FailureRespiratory Failure3 moreThe objective of the RATE-trial is to study if reduced anticoagulation targets during ECLS diminish bleeding complications without an increase in thromboembolic complications or a negative impact on outcome.
DOT HeartMate 3 Study
LVAD (Left Ventricular Assist Device) ThrombosisA prospective, single-center, randomized controlled trial of the feasibility and safety of apixaban in HeartMate 3 patients.
Feasibility of an Early Initiated Physiotherapy Intervention Among Patients With Deep Vein Thrombosis....
Deep Vein ThrombosisThe project will investigate the feasibility of a physiotherapy intervention for patients diagnosed with deep vein thrombosis for whom a physiotherapy intervention is not currently part of clinical practice in Denmark. Specifically, the project will investigate if an early-initiated physiotherapy intervention for patients who are admitted acutely with first-time deep vein thrombosis (DVT), can be carried out and is experienced as valuable for the patients.
Comparative Effectiveness of Pulmonary Embolism Prevention After Hip and Knee Replacement
Pulmonary EmbolismVenous ThrombosisPEPPER is a randomized study comparing the three most commonly used anticoagulants in North America in patients who have elected to undergo primary or revision hip or knee joint replacement surgery. The anticoagulants being compared are enteric coated aspirin, low intensity warfarin, and rivaroxaban.
Suture Closure AFtEr VEIN Access for Cardiac Procedures (SAFE-VEIN) Trial
Atrial FibrillationAtrial Flutter6 morePrimary objective: To compare the safety and efficacy of closure strategies post venous access procedures. Hypothesis: We anticipate that the use of a venous closure device will decrease the time to hemostasis (TTH), time to ambulation (TTA) and time to discharge (TTD) compared to conventional methods of closure following venous access procedure.
The Effectiveness and Safety of 4% Sodium Citrate as a Lock Solution in Central Venous Hemodialysis...
Central Venous Catheter ThrombosisRenal DialysisStudies that used a dilute citrate formulation (4%) demonstrated efficacy as an anticoagulant with minimal to no risk of bleeding in HD sessions. This study will compare effectiveness and safety utilizing 4% sodium citrate vs. heparin as a lock solution in central venous hemodialysis catheter among hemodialysis patients.