Impact of Anti-platelet Drug Exposure on Platelet mRNA Splicing in Healthy Subjects
Thrombosis; ArteryThe purpose of this pilot study is to determine how the anti-platelet drug, ticagrelor, impacts platelet mRNA splicing after a single loading dose in 10 healthy participants. These results will be valuable in that they will help inform our analysis of platelet RNA splicing after a thrombotic event.
Evaluation of the Short and Long Term Performance and Clinical Outcomes of the Crux Vena Cava Filter...
Pulmonary EmbolismVenous Thromboembolism1 moreThe Crux Vena Cava Filter (VCF) Registry is a clinical study, sponsored by Volcano Corporation, to evaluate the short and long term performance and clinical outcomes of the Crux Vena Cava Filter System.
BRAVO - Betrixaban Registry Using Real Time Observations in Acute Medical Illness to Assess Venous...
Venous ThrombosesPart 1 - Evaluate the real-world implementation of extended prophylaxis with betrixaban in the acutely ill hospitalized medical population Part 2 - Describe patterns of Venous thromboembolism (VTE) prophylaxis in acutely ill medical patients who qualify for extended VTE prophylaxis
The Correlation of a D-dimer Testing Protocol With Venous Thromboembolism in Surgical Colorectal...
Venous ThrombosesColorectal Cancer4 moreThe purpose of this study is to evaluate the use of a D-dimer based protocol to screen for thrombotic events in colorectal surgical patients. This study is unique because of the multistage screening process for DVT's using a standardized D-dimer testing methodology and ultrasound that will take place throughout the preoperative, perioperative, and postoperative processes. The data collected from this screening study will help establish the baseline DVT rates in UTMB's colorectal surgical patients before and after surgery. Additionally, the data from this study can help determine if a D-dimer blood test has predictive value in UTMB's colorectal surgical patient population. This study may also provide preliminary evidence for further research regarding the adjustment of D-dimer cutoff values. Specifically for patient subsets such as surgical colorectal patients with a moderate pretest probability and clinical conditions associated with low test specificity
The 36-month Extension to Follow up Sub Study
Postphlebitic SyndromePost-Thrombotic Syndrome1 moreThe purpose of this study is to evaluate leg health for one additional year in patients with symptomatic proximal deep venous thrombosis who did not already develop Post-Thrombotic Syndrome (PTS) during the 2 years of follow up in the SOX Trial.
Portal Vein Thrombosis in Cirrhosis
Hepatic Vein ThrombosisCirrhosisThis study evaluates the supervivence of cirrhotic patients that develop portal vein thrombosis in comparison to cirrhotic patients that do not develop portal vein thrombosis.
Molecular and Cellular Mechanisms of the In-stent-thrombosis
Patients With SAT or LT After Stent Implantation (PCI)In-Stent-Thrombosis is a rare but serious complication after implantation of stents during PTCA.
Thrombotic Biomarkers to Predict Thrombosis in Heparin-induced Thrombocytopenia
Heparin-Induced ThrombocytopeniaThrombosis1 moreHeparin induced thrombocytopenia (HIT) is a kind of catastrophic thrombotic complications after the application of heparin. If HIT without treatment, death rate is as high as 30% to 50%. Early diagnosis of HIT and prevention of thrombosis is very important. This study is planned to assess the use of thrombotic biomarkers in patients with HIT, including thrombin-antithrombin complex, d-dimer, fibrin degradation products and Thrombelastograghy monitoring . These biomarkers are monitored in 5-14 days post-operation to assess the risk of thrombosis in HIT patients. All patients were followed up for 30 days, and clinical outcomes, including new thrombus and death, were recorded during follow-up.
Association of Cytokines With the Development of Complications in Burn and Toxic Epidermal Necrolysis...
Inflammatory ResponseMulti Organ Failure2 moreThis study will involve blood draws to test for specific cytokines. The study goal is to gain a better understanding of the role of inflammatory response in the development of specific complications in burn and TENS patients.
Primary Upper Limb Deep Vein Thrombosis. Is First Rib Resection Necessary?
Paget Schroetter SyndromeThe purpose of the study is to compare outcome of patients with effort thrombosis who were treated operatively to those treated nonoperatively