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Active clinical trials for "Hematologic Diseases"

Results 231-240 of 364

Parenting Skills Intervention in Improving Medication Adherence in Pediatric Cancer Patients

GuardianHematologic and Lymphocytic Disorder2 more

This trial studies how well a parenting skills intervention works in improving medication adherence in pediatric cancer patients. The parenting skills intervention provides support and skills training to parents who administer medicine daily to their child and may improve the childs taking of medications correctly as prescribed by the doctor. Ultimately, this may improve treatment outcomes, among children who are experiencing an illness.

Completed12 enrollment criteria

Traditional Chinese Medicine in the Supportive Management of Anaemic and Cytopenic (Leukopenia,...

Myelodysplastic Syndrome (MDS)Aplastic Anaemia (AA)2 more

The purpose of this study is to study the efficacy of Traditional Chinese Medicine (TCM) on anaemic and cytopenic haematological disorders including myelodysplastic syndrome (MDS), aplastic anaemia (AA), myelofibrosis (MF) and thalassemia intermedia who do not have or did not respond to available treatment options.

Completed11 enrollment criteria

Evaluation of Therapeutic Plasma Exchange (TPE) Procedure Using the AMICUS Device

Autoimmune DiseasesRenal Disorders2 more

This study will evaluate the use of the AMICUS device in patients where Therapeutic Plasma Exchange (TPE) is prescribed by their physicians.

Completed7 enrollment criteria

Safety and Tolerability Evaluation of MaaT033

Hematologic DiseasesChemotherapy Effect

Richness and diversity of gut microbiota are increasingly found to be associated with cancer outcomes. Moreover, an adequately responsive immune system seems to rely on the existence of a functioning gut ecosystem that includes the microbiota and its natural environment. Cancer by itself, but also cancer treatments - in particular chemotherapy - induce gut dysbiosis, impair the constant reparation mechanisms of the gut epithelium, disrupt immune homeostasis, and stunt immune responsiveness. The objective of MaaT033 is to (1) prevent the decay of the gut ecosystem (dysbiosis) to preserve immune homeostasis, (2) restore and optimize the gut ecosystem to full functionality including its role in repairing the gut epithelium and healthy gut barrier, and (3) maintain a restored gut ecosystem and fully functional immune homeostasis. Restoring the full gut ecosystem and its associated microbiota could become an important therapeutic option to improve clinical outcomes and control adverse events of conventional approaches, including immunotherapy in cancer patients. As a first step, MaaT033 capsules containing lyophilized, pooled, full-ecosystem microbiota in its natural environment are to be tested for their safety and tolerability in hematological malignant patients, who are exposed to intensive rounds of chemotherapy and antibiotics.

Completed28 enrollment criteria

Pharmaco-economic Study of a New Medical Device Performed From the Perspective of the Hospital

Hematologic Disease

The purpose of the study is to determine whether the use of mouthwashes Caphosol ™ in addition to standard oral care (strategy A) is cost-effective in the prevention and treatment of severe mucositis in adult patients with auto or allograft packaging without ICT versus mouthwashes standard bicarbonates with an antiseptic (strategy B).

Completed15 enrollment criteria

Mesenchymal Stem Cells for Treatment of Poor Graft Function After Allogeneic Hematopoietic Stem...

Stem Cell TransplantationHematopoietic3 more

The purpose of this study is to evaluate the utility of treating patients experiencing poor graft function after allogeneic hematopoietic stem cell transplantation with ex-vivo-expanded BM-drived mesenchymal stem cells from third-party donors. Our first objective was to evaluate the effect of such treatment on poor graft function, and second object was to investigate the safety of such treatment.

Unknown status5 enrollment criteria

Megakaryocytic Progenitor Cells for Prophylaxis and Treatment of Thrombocytopenia

Hematological DiseasesThrombocytopenia

The purpose of this study is to evaluate the efficacy of ex vivo generated megakaryocytic progenitor cells (MPs) in prophylaxis and treatment of thrombocytopenia caused by chemotherapy in patients with acute leukemia (AL).

Unknown status9 enrollment criteria

MSCs With or Without Peripheral Blood Stem Cell for Treatment of Poor Graft Function and Delayed...

Stem Cell TransplantationHematopoietic3 more

The purpose of this study is to compare the efficacy of mesenchymal stem cells (MSCs) with or without granulocyte colony-stimulating factor (G-CSF) mobilized peripheral stem cells (PBSC) in treating patients experiencing poor graft function or delayed platelet engraftment after allogeneic hematopoietic stem cell transplantation.

Unknown status5 enrollment criteria

Mesenchymal Stem Cells Combined With Cord Blood for Treatment of Graft Failure

Hematopoietic Stem Cell TransplantationMesenchymal Stem Cells3 more

The purpose of this study is to evaluate the utility of treating patients experiencing graft failure after autologous hematopoietic stem cell transplantation with ex-vivo-expanded BM-drived mesenchymal stem cells from third-party donors or mesenchymal stem cells combined with cord blood. The first objective of this study was to evaluate the effect of such treatment on graft failure, and second object was to investigate the safety of such treatment.

Unknown status5 enrollment criteria

MSC for Treatment of CMV Infection

Stem Cell TransplantationHematopoietic2 more

The purpose of this study is to evaluate the efficacy of mesenchymal stem cells (MSC) in the treatment of refractory cytomegalovirus (CMV) infection after allogeneic hematopoietic stem cell transplantation (allo-HSCT).

Unknown status5 enrollment criteria
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