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Active clinical trials for "Blood Loss, Surgical"

Results 161-170 of 173

New Techniques to Reduce Intra-operative Bleeding During Complex Liver Resection

Surgical Blood Loss

This observational study introduced an new advanced bleeding control strategy during complex liver resection.This newly described "stepwise vascular control" technique was efficacious and feasible to control intra-operative bleeding in complex hepatectomy involving second hepatic hilum and retro-hepatic inferior vena cava.

Completed3 enrollment criteria

Single Dose of Tranexamic Acid and Blood Loss, in Elderly Patients With Hip Fracture

Blood LossSurgical3 more

The aim of this study is to investigate the hypothesis that single dose of tranexamic acid (TXA) preoperatively will lower blood loss and transfusion rate in elderly patients with hip fractures (intertrochanteric or Subcapital), that will be treated with intramedullary nailing and cemented hemiarthroplasty respectively. After application of inclusion and exclusion criteria, patients will be randomized in two groups. Group 1 will include patients that receive preoperatively single dose of TXA (15mg/kg) and Group 2 will include patients that receive normal saline (control group).

Unknown status10 enrollment criteria

French One Day Survey in 2011 - Knowing Our Population of Labile Blood Products Recipients

Blood Product Transfusion for All ConditionsTrauma2 more

Describe the epidemiologic profile and clinical context of transfusion recipients in France. Describe the clinical context of transfusion. Describe the characteristics of the transfusion prescriptions, the use of blood products and the main indications for transfusion. Describe transfusion practice according the type of hospital stay.

Completed2 enrollment criteria

HemoSonics - UTMB Cardiac Surgery Study

Blood LossSurgical

This study will evaluate the performance of the Quantra System comprised of the Quantra Hemostasis Analyzer with the Quantra QPlus Cartridge in patients undergoing cardiac surgery utilizing cardiopulmonary bypass, including the placement of a ventricular access device.

Completed9 enrollment criteria

QStat in Liver Transplant

Blood LossSurgical

This study will assess the clinical performance of the Quantra System with the QStat Cartridge in the liver transplant population.

Completed8 enrollment criteria

Observational Cohort Study of TachoSil (TC-018-IN)

Blood LossSurgical

The purpose of this study is to collect information, after exposure to TachoSil ®, of all thromboembolic events, immunological events and drug interactions leading to thromboembolic events or major bleeding. In addition, pharmacoeconomic data will be collected.

Completed2 enrollment criteria

Evaluation of the Clinical Performance of the Quantra System With the Quantra Surgical Cartridge...

Blood LossSurgical

This study will evaluate the performance of the Quantra System comprised of the Quantra Hemostasis Analyzer with the Quantra Surgical Cartridge in patients undergoing major surgical procedures specifically, major cardiac and vascular procedures and major orthopedic surgery (primarily complex spine surgeries).

Completed12 enrollment criteria

Fresh Frozen Plasma in Cardiac Surgery: Descriptive and Prognostic Study

Heart SurgeryBlood Loss1 more

Despite experts' recommendations, the consumption of Fresh frozen plasma (FFP) is very heterogeneous among French cardiac surgery centers. This probably reflects heterogeneous practices that are not characterized and whose outcomes on morbidity and mortality are not documented. The principal objective of the study is to describe transfusional strategies of FFP in patients undergoing cardiac surgery. The other objectives are: to assess the conformity of FFP transfusion or lack of transfusion to current French authorities' recommendations, to describe the post-operative mortality and morbidity and to assess the prognostic role of FFP on mortality and morbidity. Prognostic analyses will take into account other prognostic factors of mortality and morbidity. 1500 patients undergoing cardiac surgery and presenting with a serious bleeding (or transfused with FFP without bleeding) will be included in the study.

Completed4 enrollment criteria

Relationship Between Temperature and Intraoperative Bleeding in Patients Undergoing Multilevel Spinal...

BleedingAnemia

The primary objective of this multicentric observational study is to define the role of intraoperative temperature decrease (defined as reduction of at least 1 ° C during surgery) as haemorrhagic risk factor, evaluated as reduction of at least 1 gr / dl of hemoglobin, and to correlate it with the need for transfusion. Secondary objectives are infections and complications affecting other organs and systems incidence in the first week after surgery.

Unknown status8 enrollment criteria

Modeling of the Hemoglobin Drop in the Uncomplicated Postoperative Course

Surgical Blood LossSurgery1 more

transfusion-related decisions in the perioperative setting are often complex due to acute variations in the hemoglobin levels, which typically experience a progressive decrease within days. This process, commonly referred to as "hemoglobin drop" or "hemoglobin drift", has been observed to be highly variable among patients and reliant on several variables, such as the volemic status, fluid balance and blood loss. Although it has been investigated and some predictors have been identified, postoperative hemoglobin drop remains unpredictable and is not fully clarified. In consequence, hemoglobin levels' variations are frequently misunderstood, hindering the decision to transfuse.

Unknown status7 enrollment criteria
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