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Active clinical trials for "Bone Diseases"

Results 51-60 of 229

Improving Phosphate Control in Children With CKD

Chronic Kidney DiseasesHyperphosphatemia3 more

Research goals: To explore the views and baseline knowledge of children and young people (CYP) with CKD and their caregivers to develop effective phosphate educational materials (PEM), adapted for age, and acknowledging different learning styles

Not yet recruiting8 enrollment criteria

A Study of Ibandronate (Bondronat) in Participants With Metastatic Bone Disease

Pain; Bone Neoplasms; Neoplasm Metastasis

This study will evaluate the efficacy, safety, and effect on quality of life of oral ibandronate (Bondronat) in participants with breast cancer and metastatic bone disease. The anticipated time on study treatment is 25 weeks, and the target sample size is 50 individuals.

Completed8 enrollment criteria

European Transplant Registry of Senior Renal Transplant Recipients on Advagraf

Graft FailureDeath8 more

SENIOR transplant Registry European transplant registry of senior renal transplant recipients (above the age of 65 years) receiving initial immunosuppression with tacrolimus once daily, mycophenolate and steroids to investigate long term outcomes on an observational basis.

Not yet recruiting17 enrollment criteria

A Study to Evaluate Renal Safety of Intravenous Ibandronate (Bondronat) in Participants With Metastatic...

Pain; Bone Neoplasms; Neoplasm Metastasis

This study will evaluate renal function in participants with metastatic bone disease due to breast cancer receiving intravenous (IV) infusions of ibandronate (Bondronat) 6 milligrams (mg), over either 15 minutes or 60 minutes, every 3 weeks. Efficacy and safety of ibandronate in the 2 groups of participants will also be compared. The anticipated time on study treatment is 7 months, and the target sample size is 318 individuals.

Completed18 enrollment criteria

Free Nonvascularized Fibula Autograft for Tumor-like Lesions in Femoral Neck Using in Pediatric...

Bone Diseases

This study was to evaluate the safety and efficacy of free nonvascularized fibula autograft in the treatment of the femoral neck tumor-like lesions before epiphyseal closure in pediatric patients, by presenting the clinic-radiological outcome and complications.

Completed4 enrollment criteria

Study to Evaluate the Safety and Effects AZD0530 on Prostate and Breast Cancer Subjects With Metastatic...

Breast CancerProstate Cancer1 more

The purpose of this study is to determine the effect of AZD0530 on subjects with breast cancer or prostate cancer with metastatic bone disease in comparison to zoledronic acid.

Completed7 enrollment criteria

Efficacy of Pamidronate in the Treatment of Bone Loss Associated With Liver Transplant

Bone DiseaseMetabolic

The aims of this study are to prospectively evaluate the efficacy of two intravenous infusions of pamidronate 90 mg, associated with calcium and calcidiol, in the early post-transplant period, on bone loss in liver transplant recipients, and to asses the safety of this treatment.

Completed7 enrollment criteria

Impact on Reducing the Incidence of Low Serum Calcium by Providing Educational Materials on the...

Paget's Disease of the BoneHypocalcemia

This study will evaluate the impact of investigator and patient education and educational materials to foster calcium and vitamin D supplementation to mitigate the potential for hypocalcemia post Reclast® administration in patients with Paget's disease of bone.

Completed3 enrollment criteria

Effect of Exercise and Phytoestrogen on Bone, Metabolic Syndrome Criteria and Complaints of the...

Bone DiseasesMetabolic Syndrome X1 more

The aim of the study is to compare the effect of a progressive, periodized exercise training designed to impact bone, CHD-risk-factors and menopausal complaints versus the combined effect of exercise and "phytoestrogen" (cimicifuga racemosa; CR). After randomization, 84 females 1-3 year postmenopausal with no medication or illness affecting bone metabolism exercise over 12 months (EG; 42 with, 42 without CR), 42 women serve as wellness-control. Three group training sessions/week will be performed in the EG. Both groups will be individually supplemented with calcium and Vit-D (cholecalciferol).

Terminated10 enrollment criteria

A Study to Evaluate Food Effect on ONO-5920/YM529 Intermittent Formulation

OsteoporosisOsteoporosis2 more

The aim of the study is to evaluate the effects of food intake on the plasma concentration profile of YNO-5920/YM529 in post menopausal women.

Completed6 enrollment criteria
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