A Multicentre, Randomised, Open-Label Study To Compare The Efficacy And Safety Of Azithromycin For...
BronchitisChronicThis study compared the clinical efficacy and safety of azithromycin with that of amoxicillin-clavulanic acid, in patients between the ages of 35 and 75 years, presenting with an exacerbation of chronic bronchitis.
The Effects of Tiotropium on the Cough Reflex in Patients With Chronic Obstructive Pulmonary Disease...
Chronic Obstructive Pulmonary DiseaseChronic BronchitisDoes tiotropium effect the cough reflex in patients with COPD and chronic bronchitis.
Telithromycin: in the Treatment of Acute Exacerbation of Chronic Bronchitis in Adult Outpatients...
BronchitisChronicNon-inferiority efficacy of telithromycin versus azithromycin
A Study of the Safety and Effectiveness of Levofloxacin Compared With Cefaclor in the Treatment...
BronchitisBronchitis1 moreThe purpose of this study is to evaluate the safety and effectiveness of levofloxacin, an antibiotic, compared with cefaclor, another antibiotic, in the treatment of adults with chronic bronchitis experiencing rapid onset of worsening of symptoms caused by bacteria.
Postoperative Rehabilitation After Cardiac Surgery in Patients at Risk of Respiratory Complications....
Scheduled Cardiac SurgerySternotomy3 morePostoperative pain after cardiac surgery is a risk factor for postoperative complications. In cardiac surgery, pain is more intense during the first 48 hours and disturbs the patient's capacity of coughing, deep breathing, and early mobilisation. It may be responsible for respiratory complications such as bronchial or pulmonary infection, and may also delay the patient's rehabilitation and therefore prolong the duration of in-hospital stay. A previous pilot study performed in our department showed a sensible improvement of analgesia at movement and of rehabilitation with a continuous bilaterosternal infusion of local anaesthesia [Eljezi et al.. Reg Anesth Pain Med 2012; 37:166]. Such strategy shall be tested in a subpopulation of patients at risk for respiratory complication.
Examining the Genetic Factors That May Cause Chronic Obstructive Pulmonary Disease (COPD)
Pulmonary DiseaseChronic Obstructive3 moreChronic obstructive pulmonary disease (COPD) is a long-term lung disease that is often caused by cigarette smoking. The purpose of this study is to evaluate whether certain genetic factors predispose some smokers to develop COPD more than others.
A Multicenter, Randomized, Double-blind, Parallel Group Study to Determine the Optimal Dose of HL301...
Acute BronchitisAcute Exacerbations of Chronic BronchitisThe purpose of this study is to determine the optimal dose of HL301 in patients with acute bronchitis or acute exacerbations of chronic bronchitis. - BSS(Bronchitis Severity Score), BCSS(Breathlessness, Cough, and Sputum Scale), evaluation of symptoms of cough and sputum
Efficacy of Losartan in Preventing Progression of COPD
COPDEmphysema2 moreEvidence in animals shows that losartan can prevent or reverse inflammation and lung damage due to smoking. The goal of this study is to determine whether this drug which is also used to treat hypertension can stabilize or improve lung function in people who have from chronic obstructive pulmonary disease (COPD).
A Blinded Study Comparing the Safety and Efficacy of a Fully Human Anti-IL8 Monoclonal Antibody...
Pulmonary DiseaseChronic Obstructive2 moreTo determine if ABX-IL8 will improve shortness of breath.
Effect of Losartan on Airway Mucociliary Dysfunction in Patients With COPD and Chronic Bronchitis...
COPDChronic BronchitisThe purpose of this study is to evaluate the effect of Losartan on cigarette smoke-induced lung injury in smokers and ex-smokers with and without chronic obstructive pulmonary disease (COPD).