Blood Test to Measure DNA Damage in Blood
Prostate CancerTo check the radiosensitivity level in individual patients based on their DNA damage level.
Imaging of Prostate Cancer Using Two-dimensional MR Spectroscopy and Diffusion Tensor Imaging
Prostate LesionsThe goal is to develop MR imaging techniques to improve delineation of cancer extent, and to improve differential diagnosis between prostate cancer and benign prostate hyperplasia or other benign diseases.
Prostate Cancer Diagnosis Through NMR Spectroscopy of Semen and Prostatic Secretions
Prostate CancerTo develop the hypothesis that quantitative NMR spectroscopy of human semen can be used to diagnose prostate cancer.
ExoDx Prostate Evaluation in Prior Negative Prostate Biopsy Setting
Prostate CancerThe study is designed to confirm the performance of the ExoDx Prostate test in prior negative biopsy patients now presenting for a repeat prostate biopsy. Note: ExoDx Prostate test results are collected for correlation to biopsy results and are not disclosed to the physician or study subject.
Transrectal Photoacoustic Imaging of the Prostate
Prostate CancerThe purpose of this study is to image human prostate tissue using a new transrectal photoacoustic imaging probe and correlate this with ultrasound and MRI imaging performed once the specimen has been surgically removed. We hope to see what we can visualize with our device as this has never been done before. Eventually, we hope to use a similar device to image the prostate in men being seen by their doctor for prostate cancer.
Soft Tissue Detection on MRI, Cone Beam CT and Fan Beam CT and Integration of Functional MRI
Lung CancerProstate CancerThis clinical trial studies magnetic resonance imaging (MRI), cone beam computed tomography (CT), and fan beam CT in detecting soft tissue in patients with prostate and lung cancer undergoing radiation therapy. Comparing results of diagnostic procedures done before and during radiation therapy may help doctors predict a patient's response to treatment and help plan the best treatment.
Using Walk With Ease Walking Program With Men 65 and Older Being Treated for Prostate Cancer
Prostate CancerThis study is testing a walking program called Walk with Ease by the Arthritis Foundation with men undergoing treatment for prostate cancer. The researchers are interested in how easy or difficult it is for these men to participate in this program and whether or not is is helpful to them during their care.
Molecular Characterization of CTCs and ctDNA in Blood and Plasma Samples From Patients With Metastatic...
Hormone-Resistant Prostate CancerMetastatic Prostate CarcinomaThis research trial studies molecular characterization of circulating tumor cells (CTCs) and circulating tumor (ct) deoxyribonucleic acid (DNA) in blood and plasma samples from patients with prostate cancer that has spread to other places in the body and/or has not responded to previous treatment with hormones. Studying samples of blood and plasma collected from patients with prostate cancer before, during, and/or after treatment in the laboratory may help doctors learn more about changes that occur in DNA and identify the development of drug resistance.
Micro-RNA Expression Profiles in High Risk Prostate Cancer
Prostate CancerRadical ProstatectomyThe purpose of this study is to determine whether specific Micro-RNA expression profiles are related to Prostate cancer outcome.
Clinical Study Evaluating Targeted Biopsies and Cytological Imprints in Prostate Cancer
Prostate CancerThe investigators will evaluate the accuracy of performing cytological imprints of targeted biopsies when diagnosing prostate cancer. It is useful to know whether the biopsy is cancer or not, in order to know when to stop sampling and when to continue. The strategy is used in other types of cancer, e.g lung, breast etc