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Active clinical trials for "Biliary Tract Neoplasms"

Results 261-270 of 325

A Study of Selective HDAC6 Inhibition With KA2507 in Advanced Biliary Tract Cancer

Biliary Tract Cancer

To evaluate the preliminary efficacy of KA2507 (an orally active potent and selective HDAC6 inhibitor) in patients with advanced biliary tract cancer (BTC) previously treated with standard of care chemotherapy.

Withdrawn36 enrollment criteria

FOLFIRI as Salvage Treatment in Metastatic Biliary Tract Cancer (BTC) Patients Who Were Failed After...

Biliary Tract Cancer

FOLFIRI as a salvage treatment in metastatic biliary tract cancer (BTC) patients who failed gemcitabine containing chemotherapy

Withdrawn4 enrollment criteria

A Randomized, Open-Label, Comparative, Parallel-Group, Multicenter Study of SPARC1507

Advanced Biliary Tract Cancer

An open label study to determine the efficacy and safety of SPARC1507

Withdrawn8 enrollment criteria

Comparing Endoscopic Based Stent Strategy Versus Bypass Surgery in Non-resectable Periampullary...

Pancreatic NeoplasmsBiliary Tract Neoplasms1 more

Randomized study comparing endoscopic stent insertion strategy versus double-bypass surgery in non-resectable periampullary cancer

Withdrawn7 enrollment criteria

Parenteral Nutrition in Patients With Biliopancreatic Mass Lesions

Weight LossPancreatic Cancer1 more

Patients with biliopancreatic tumors are at risk for malnutrition and have to undergo many procedures for diagnostic workup that require fasting periods. In a prospective randomized monocentric study we evaluate the effect of additional parenteral nutrition on weight loss, nutritional status, quality of life and length of hospital stay.

Completed7 enrollment criteria

Programs To Support You During Chemotherapy

DepressionFatigue19 more

This randomized pilot trial studies how well two supportive programs work for improving fatigue and depressive symptoms in patients with GI undergoing chemotherapy. Possible mediators such as psychological stress, circadian disruption, and inflammation, will also be explored.

Completed4 enrollment criteria

Effect of Early Management on PAin and DEpression in Patients With PancreatoBiliary Cancer, EPADE-PB...

Pancreatic CancerBiliary Tract Cancer2 more

Effect of Early management on PAin and DEpression in patients with PancreatoBiliary Cancer, EPADE-PB Purpose To determine whether early palliative care integrated with usual oncologic care with automated symptom monitoring can improve depression and pain in patients with cancer

Completed11 enrollment criteria

Adjuvant Palliative Capecitabine and Gemcitabine in Treating Patients With Locally Advanced or Metastatic...

Extrahepatic Bile Duct CancerGallbladder Cancer2 more

RATIONALE: Drugs used in chemotherapy, such as capecitabine and gemcitabine, use different ways to stop tumor cells from dividing so they stop growing or die. Palliative chemotherapy may improve the quality of life in patients who have locally advanced or metastatic biliary tract cancer and may help them live more comfortably. PURPOSE: Phase II trial to study the effectiveness of adjuvant capecitabine and gemcitabine in improving quality of life in patients who have locally advanced or metastatic biliary tract cancer.

Completed74 enrollment criteria

Patient Activation Through Counseling, Exercise and Mobilization

Pancreas CancerBiliary Tract Cancer2 more

PACE-Mobil-PBL is a prospective randomized controlled trial. The aim is to investigate the effect of a multimodal and exercise-based intervention among older patients with advanced pancreatic cancer, biliary tract cancer, or lung cancer during treatment with first-line palliative chemotherapy, immunotherapy or targeted therapy. The hypotheses: That the multimodal intervention will increase or maintain physical function levels and strength, reduce symptoms and side-effects, improve quality of life, reduce treatment-related complications and hospital admissions, and reduce risk of cancer cachexia and sarcopenia.

Completed12 enrollment criteria

CureOne Registry: Advanced Malignancy or Myelodysplasia, Tested by Standard Sequencing and Treated...

NeoplasmsLung Neoplasms23 more

Registry participants with advanced malignancy or myelodysplasia will have a sample of their tumor or tissue analysed for genetic alterations using next generation sequencing (NGS) performed in a lab that has been certified to meet a high quality standard. Treatments and outcomes will be reported to the registry to allow further understanding of how genetic differences can lead to better diagnosis and treatments.

Terminated13 enrollment criteria
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