search

Active clinical trials for "Head and Neck Neoplasms"

Results 1071-1080 of 1835

Feasibility Study of Incorporating 18F-FDG-PET Imaging in Radiotherapy for Head and Neck Cancer...

Head and Neck Neoplasms

The purpose of this trial is to study fluorodeoxyglucose-positron emission tomography (FDG-PET)-based dose escalation using intensity modulated radiation therapy (IMRT).

Completed6 enrollment criteria

Paclitaxel, Carboplatin And Low Dose Radiation As Induction Therapy In Locally Advanced Head And...

Squamous Cell Carcinoma

This study is being performed utilizing two cycles of Paclitaxel and Carboplatin, plus low doses radiation as initial therapy prior to other treatment (surgery or radiation). The study is assessing if utilization of low doses radiation as a chemoenhancer will further increase the response rate seen with initial therapy.

Completed20 enrollment criteria

Palliative Radiotherapy Protocol in Head and Neck Cancer

Head and Neck NeoplasmsQuality of Life

Phase II prospective study or Palliative Radiotherapy of 25 Gy in 5 fractions, Intensity Modulated, for frail patients with incurable head and neck cancer. Comprehensive Quality of life (QLQ-C30, head and neck module, QLQ C15 PAL) and toxicity data (CTCAE v 4.0) collected.

Completed10 enrollment criteria

A Study to Assess the Efficacy of Early Physical Therapy Intervention Following a Modified Unilateral...

Shoulder Weakness Following Neck Dissection Surgery

This study will determine whether patients who receive regular physical therapy immediately following a modified neck dissection surgery will report decreased shoulder disability, decreased pain, improved or maintained shoulder range of motion and strength, and improved quality of life than those who receive only home instruction.

Completed10 enrollment criteria

A Study of Cisplatin Plus Radiotherapy Compared to Cetuximab Plus Radiotherapy in Locally Advanced...

Locally Advanced Head and Neck Cancer

The primary endpoint in this study is to investigate if there is a difference in overall survival in patients with locally advanced head and neck cancer, randomized to either radiotherapy and cetuximab or radiotherapy and cisplatin. A second randomization is performed in patients with T3-T4 tumors; allocated radiotherapy either 68.0 Gy or 73.1 Gy.

Completed21 enrollment criteria

Swallowing Intervention During Radiochemotherapy on Head and Neck Cancer

Head Neck CancerSwallowing Disorders

General Objective: To evaluate the swallowing results of speech pathologist rehabilitation of advanced oropharynges, larynx and hypopharynx cancer patients during neoadjuvant chemotherapy and radiotherapy concomitant to chemotherapy. Methods and Casuistic: Randomized clinical trial phase II. 80 patients with advanced oropharynges, larynx and hypopharynx cancer diagnoses from Barretos Cancer Hospital, which had the proposal of neoadjuvant chemotherapy followed by radiotherapy combined with chemotherapy. Patients are randomized on two groups: control group and speech pathology therapy group

Completed10 enrollment criteria

Feasibility of IMRT Modulation to Account for Scattered Radiation From Dental Fillings in Head and...

Head and Neck Cancer

The main objective of this study is to determine the feasibility of optimizing the IMRT treatment plan based on dosimeter measurements of mucosal radiation dose adjacent to the dental fillings to reduce such dose to < 35 Gy without compromising tumor coverage and/or increasing the dose to the remaining oral cavity or nearby parotid glands.

Completed7 enrollment criteria

A Phase II, Open-Label, Multicenter Trial of Cabazitaxel in Patients With Recurrent or Metastatic...

Recurrent Head and Neck CancerMetastatic Head and Neck Cancer

This is a multi-center phase II study assessing whether cabazitaxel could be efficient for treatment of recurrent or metastatic head and neck cancer after failure of cisplatin, cetuximab and taxanes.

Completed31 enrollment criteria

Adaptive Dose-Escalated Multi-modality Image-guided RadiothErapy

Head and Neck Cancer

Patients with primary head and neck squamous cell carcinoma (HNSCC) planned for treatment with radiotherapy with or without chemotherapy in curative setting will be treated with an adaptive radiotherapy scheme. An FDG-PET/CT scan for re-delineation and re-planning will be made at the end of the second and fourth of week of radiotherapy. The non-responding part of the tumor on FDG-PET will receive a mild dose-escalation. Depending on the metabolic response, the entire tumor will receive 70 Gy or the residual FDG-avid area will receive 74 or 78 Gy.

Completed5 enrollment criteria

Use of Multiparametric MRI in the Management of Head and Neck Cancer: a Prospective Analysis

Head and Neck CancerMultiparametric MRI4 more

The investigators aim to validate specific MRI parameters that could improve diagnostic accuracy of metastatic cervical lymph nodes in patients with a squamous cell carcinoma in the head and neck region. Moreover, we aim to explore specific MRI parameters that could improve diagnostic accuracy of bone invasion and tumour relapse, as well as predict treatment response and survival in this target population.

Active8 enrollment criteria
1...107108109...184

Need Help? Contact our team!


We'll reach out to this number within 24 hrs