search

Active clinical trials for "Head and Neck Neoplasms"

Results 1461-1470 of 1835

Tranexamic Acid and Head and Neck Surgery Patients

Head and Neck Neoplasms

Tranexamic acid belongs to fibrinolytic inhibitors. Several prospective randomized clinical trials have proved its effectiveness in reducing intra-operative and post-operative bleeding in orthopedic and cardiovascular surgeries. However, there is little study about tranexamic acid in reducing post-operative bleeding in head and neck surgery. So the aim of this study is to investigate if tranexamic acid could reduce post-operative bleeding via prospective double-blinded randomized clinic trial.

Unknown status4 enrollment criteria

Study of Imatinib (Glivec) in Patients With Adenoid Cystic Carcinoma of the Head and Neck

Cancer of the Head and NeckCarcinoma1 more

This is a Phase II study of imatinib (Glivec) administered as a daily oral treatment in patients with recurrent/metastatic adenoid cystic carcinoma of the head and neck overexpressing KIT.

Unknown status14 enrollment criteria

Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole

Squamous Cell CarcinomaHead and Neck Neoplasms2 more

The purpose of this clinical research study is to answer the following questions using 18F-fluoromisonidazole as an imaging agent: Do cells exist in human tumors that are at very low oxygen levels (hypoxic cells)? If hypoxic cells exist in human tumors, do they effect the ability of radiotherapy to control human tumors? Can Positron Emission Tomography (PET scanning) detect hypoxic cells in human tumors?

Withdrawn8 enrollment criteria

Cisplatin Plus Epinephrine in Treating Patients With Recurrent or Refractory Head and Neck Cancer...

Head and Neck Cancer

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known if treatment with cisplatin plus epinephrine is effective for head and neck cancer. PURPOSE: Randomized double-blinded phase III trial to determine the effectiveness of cisplatin plus epinephrine in injectable gel form in treating patients who have recurrent or refractory head and neck cancer.

Unknown status3 enrollment criteria

Surgery and Radiation Therapy With or Without Interleukin-2 in Treating Patients With Cancer of...

Head and Neck Cancer

RATIONALE: Interleukin-2 may stimulate a person's white blood cells to kill cancer cells of the mouth or oropharynx. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not known whether giving interleukin-2 with surgery and radiation therapy is more effective than surgery and radiation therapy alone. PURPOSE: This randomized phase III trial is studying surgery and radiation therapy alone to see how well they work compared to surgery, radiation therapy, and interleukin-2 in treating patients with cancer of the mouth or oropharynx.

Unknown status59 enrollment criteria

Photodynamic Therapy in Treating Patients With Recurrent, Refractory, or Second Primary Head and...

Head and Neck Cancer

RATIONALE: Photodynamic therapy uses light and drugs that make cancer cells more sensitive to light to kill tumor cells. This may be an effective palliative treatment for head and neck cancer. PURPOSE: Phase II trial to study the effectiveness of photodynamic therapy for palliative treatment in patients who have recurrent, refractory, or second primary head and neck cancer that cannot be treated with surgery or radiation therapy.

Unknown status3 enrollment criteria

Swallowing Function in Patients With Head and Neck Cancers

Head Neck CancerOral Cancer

Head and neck cancer (HNC) is the sixth most common cancer worldwide, accounting for 2.8% of all malignancies. The presence of tumor itself, as well as the treatment, can result in neuromuscular damage affecting any stage of the swallowing. Organ-sparing care has become more common in recent years, however, that this does not always imply functional preservation. Dysphagia and aspiration both can occur and can have complex causes. Normal swallowing has oral preparatory phase, pharyngeal phase, and the oesophageal phase, it is important to know what is the dysfunction and where. This study aim to evaluate the preoperative and postoperative swallowing function in patients with head neck cancer using electromyography (EMG) and video fluoroscopy.

Completed6 enrollment criteria

Robot Assisted Supraomohyoid Neck Dissection Via Retroauricular Approach

Head and Neck Neoplasms

In this study we introduce and evaluate the feasibility of our surgical technique to hide the external scar of neck dissection using the robotic system via a modified facelift or retroauricular approach.

Unknown status6 enrollment criteria

PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Safety and Tolerability in Healthy...

Diagnostic Imaging

Visual assessment of diagnostic PET/CT (positron emission tomography/computed tomography) images obtained after a single intravenous injection of BAY86-9596 in patients with cancer and inflammation

Completed12 enrollment criteria

TPF Induction With Concomitant Chemoradiation to Treat Patients With Head and Neck Cancer

Head and Neck Cancer

The purpose of this trial is to compare two different treatments for fit patients with head and neck cancer: All patients are given induction-chemotherapy (docetaxel, cisplatin, 5-FU). Subsequently patients are being randomised into two groups: The first group receives neo-adjuvant chemotherapy ('high' dose cisplatin) and conventional radiotherapy The second group receives neo-adjuvant chemotherapy ('low' dose cisplatin) and accelerated radiotherapy.

Unknown status27 enrollment criteria
1...146147148...184

Need Help? Contact our team!


We'll reach out to this number within 24 hrs