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Active clinical trials for "Skin Neoplasms"

Results 471-480 of 522

Identifying Skin Biopsy Sites

Identification of Skin Cancer Biopsy Sites

The primary objective of this study is to investigate the patient experience during skin biopsy.

Completed6 enrollment criteria

Evaluation Of The Importance Of Risk-Factor Adjustment For Assessing The Relationship Between Voriconazole...

Non-Melanoma Skin Carcinoma

The primary objective of the study is to assess the relationship (both crude and adjusted) between voriconazole utilization and the development of non-melanoma skin cancer among adult patients who received a lung or heart/lung transplant and were continuously enrolled in a large U.S. commercial health plan.

Completed2 enrollment criteria

Body Image Functioning Among Surgically Treated Patients With Head and Neck Cancer

Head and Neck CancerSkin Cancer

Objectives: The purpose of this study is to obtain descriptive information about the nature and extent of body image concerns among surgical patients with head and neck cancer, satisfaction with care received regarding body image issues, and interest in psychosocial services targeting body image disturbance. Findings from this study provide important preliminary data to guide future large scale research on the critical, yet understudied, psychosocial issue of body image functioning for head and neck cancer patients. Information obtained from this study can specifically be used to facilitate the development of appropriate disease-specific body image instruments and to determine the need for body image focused psychosocial interventions to enhance quality of life and the survivorship experience for these patients. Primary Aims To characterize the nature and extent of body image concerns in surgically treated patients with head and neck cancer and determine preferences for psychosocial intervention. To compare body image and quality of life outcomes for patients at different time points relative to initiation of treatment. Specific time points of interest are pre-treatment, within one year of initial surgical treatment, and greater than 1 year following initial surgical treatment. Secondary Aim 1. To compare body image and quality of life outcomes for patients with oral cavity, cutaneous, and midface cancers.

Completed8 enrollment criteria

Comparative Retrospective Analysis of Skin Tumors of the Eyelids and Face in 2 Brussels University...

Skin Cancer

Skin cancers are the most common of all cancers. Their incidence has increased sharply over the decades.This increase in incidence partly reflects an aging population and behavioral patterns such as repeated exposure to the sun. Indeed, exposure to UV rays is the predominant factor involved in the pathogenesis of these tumors, hence the fact that they mainly develop in photo-exposed regions such as the cephalic extremity. The objective of this study is to provide an epidemiological analysis of tumors in the populations of both CHU Brugmann and St Pierre hospitals.

Completed2 enrollment criteria

Exploratory Prospective of Experienced by Patients in the Surgery of Skin Cancers of the Face in...

Skin Cancer FaceSurgical Incision

Surgery is the first-line treatment of localized skin cancers. Knowledge on the patient's psychological experience is limited. Therefore, the psychological impact on patients before, during and after surgery can be underestimated. Moreover, the diagnosis of cancer disturbs the patient's entire life and the onset of anxiety disorders is frequent following this announcement.

Completed8 enrollment criteria

TLR4 Polymorphisms and Risk of Skin Cancer

Skin Cancer

Toll-like receptors (TLRs) play a key role in the innate immune system. Toll-like receptor-4 (TLR4) in particular, appears to play a role in susceptibility to cancer. Of 44 identified SNPs (small nucleotide polymorphisms) in TLR4, the most common is an A-G substitution at nucleotide position +896, downstream of the cDNA start codon, a missense mutation which leads to an amino acid substitution Asp299Gly in the third exon of the TLR4 gene. Pre-clinical studies from our laboratory have shown an association of TLR4 with ultraviolet radiation induced skin cancer. Hence, in this study we will assess the pattern of TLR4 polymorphisms and susceptibility to skin cancer.

Completed6 enrollment criteria

Expanded Access Study of Melphalan With Delcath CS-PHP System in Patients With Ocular/Cutaneous...

Metastatic Liver CancerOcular Melanoma1 more

The safety and efficacy of CS-PHP-melphalan has been evaluated in a phase 3 trial conducted in the same patient population as well as using the same melphalan dosing as proposed in this study. This expanded access protocol will provide an experimental alternative treatment option for both physicians and patients until the Delcath CS-PHP System receives marketing approval.

No longer available41 enrollment criteria

Potential Research Study Participant Registry

AcneActinic Keratosis8 more

The purpose of the potential research study participant registry is to keep potential research subjects informed about any future research studies in which they may meet the criteria for enrollment. The purpose of this study is also to assist current and future clinical trials with recruitment of subjects.

Completed2 enrollment criteria

A Pilot Study to Evaluate Optical Spectroscopy of Pigmented Skin Lesions

Skin Cancer

The incidence of malignant melanoma has increased dramatically in recent decades. In 1930, the lifetime risk of an individual in the United States developing melanoma was 1 in 1,500. This has been exponentially increasing over the years with the risk estimated to be 1 in 75 in 2000 . According to the American Cancer Society, approximately 59,580 new cases of melanoma will be diagnosed in the United States in 2005 and about 7,770 people are expected to die of the disease.

Completed4 enrollment criteria

Predictors of Patient Attitudes and Barriers to Skin Cancer Screening

Skin Cancer

This is a cross-sectional survey distributed to a convenience sample of patients in a waiting room of an academic dermatology clinic. The survey assesses patient experiences with full body skin exams and attitudes towards full body skin exams. The survey is designed to help investigators better understand how many patients are not getting full body skin exams, why this may be occurring, and what types of interventions may be enacted to increase the number of patients getting full body skin exams.

Completed3 enrollment criteria
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