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Active clinical trials for "Carcinoma"

Results 6941-6950 of 7825

NBI to Detect Post-RT Mucosal Residual NPC

Nasopharyngeal Carcinoma

NBI has been proven to be a useful tool to detect early NPC, but they were few studies concerning the detection of post-radiotherapy mucosal residual NPC using NBI system

Completed5 enrollment criteria

MRI With Gadoxetate Disodium in Measuring Tumors in Patients With Liver Cancer

Adult Hepatocellular CarcinomaAdvanced Adult Hepatocellular Carcinoma7 more

This pilot clinical trial studies magnetic resonance imaging (MRI) with gadoxetate disodium in measuring tumors in patients with liver cancer. Diagnostic procedures, such as MRI with gadoxetate disodium, may help find and diagnose liver cancer and find out how far the disease has spread. It is not yet known whether MRI with gadoxetate disodium provides a more precise measurement of liver tumors than standard computed tomography (CT).

Completed22 enrollment criteria

Long Term Prospective Study Evaluating Effectiveness of Narrow Margins for Low-Risk Head and Neck...

Basal Cell Carcinoma

The purpose of this study is to determine the narrowest excision margin for head and neck Basal Cell Carcinoma (BCC) tumors satisfying the National Comprehensive Cancer Network® (NCCN) low-risk for recurrence clinical and histopathological criteria that gives an acceptable (95%) clinical cure-rate over a 3 year follow-up period. Margins of 1 and 2mm are evaluated.

Unknown status14 enrollment criteria

Circulating Tumor Cells and Cytology in Cerebrospinal Fluid of Patients Clinically Suspected for...

Meningeal Carcinomatosis

The purpose of this study is to determine whether the quantitative detection of circulating tumor cells (CTCs) in patients with Epcam expressing tumors can be used compared to standard qualitative method - cytology both in the cerebrospinal fluid of patients, clinically suspected for leptomeningeal metastases.

Completed6 enrollment criteria

Laparoscopic Versus Open Liver Resection in the Treatment of Hepatocellular Carcinoma

Hepatocellular Carcinoma

The purpose of this study is to investigate the clinical value of laparoscopic liver resection in the treatment of hepatocellular carcinoma by assessing its Surgical and oncologic outcomes comparing with open liver resection.

Unknown status18 enrollment criteria

Non-comparative Study of Treatment With Induction Chemotherapy With Cisplatin and Gemcitabine Followed...

Patients Diagnosed With Advanced Carcinoma of Uterine Cervix t

The purpose of this phase II study is to determine the survival free disease of patients diagnosed with invasive locally advanced carcinomas of uterine cervix treated with induction chemotherapy with cisplatin and gemcitabine followed by chemoradiation and definitive chemoradiation.

Unknown status14 enrollment criteria

Interest of Narrow Band Imaging in Detection of Upper Aerodigestive Cancers

Squamous Cell Carcinoma of OropharynxSquamous Cell Carcinoma of Hypopharynx1 more

The aim of this study is to prospectively determine if the use of NBI endoscopy modifies the superficial extension of these tumors.

Completed4 enrollment criteria

Effectiveness of Chemotherapy in Metastatic or Recurrent Carcinoma Cervix

Metastatic Carcinoma to the Uterine CervixRecurrent Carcinoma Cervix1 more

Experience with substituting carboplatin for cisplatin is limited in advanced and recurrent cervix cancer and there has been no counterpart to GOG 158, which documented therapeutic equivalency of cisplatin/paclitaxel and carboplatin/paclitaxel for treatment of ovarian cancer, performed in a cervix cancer population.

Unknown status8 enrollment criteria

BIBF1120 in Patients With Advanced FGFR3 Mutated,Overexpressed,or Wild Type Urothelial Carcinoma...

Urothelial Carcinoma

BIBF1120 in patients with advanced FGFR3 mutated, FGFR3 overexpressed, or FGFR3 wild type urothelial carcinoma of urinary bladder, urethra, ureter, and renal pelvis and who have failed platinum-based chemotherapy.

Unknown status14 enrollment criteria

Intraoperative Imaging of Breast Cancer With Indocyanine Green

Invasive Ductal CarcinomaInvasive Lobular Carcinoma1 more

According to the World Health Organization, breast cancer is the most common cancer in women, and is responsible for 686,000 new cases every year. The WHO also posit that nearly 420,000 women perished from the disease in 2002. Surgery remains the best option for patients presenting with operable Stage I, II or III cancers. Breast conservation surgery has been shown to be as efficacious as mastectomy. About 60-70% of these women with operable breast cancer are breast conservation candidates. However, the need to achieve negative tumor margins often requires a second operation (re-excision) in up to 70% of the women having lumpectomy surgery. Currently, tumor margins assessment in the operating room is often assessed grossly by palpation. The ability to evaluate tumor margin using our proposed intraoperative imaging technique may provide the surgeon with an alternative, and hopefully, more sensitive method to assess tumor margins which may decrease re-excision and the morbidity associated with additional surgery, and, perhaps, lower the risk of local regional recurrence.

Completed11 enrollment criteria
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