
NBI to Detect Post-RT Mucosal Residual NPC
Nasopharyngeal CarcinomaNBI has been proven to be a useful tool to detect early NPC, but they were few studies concerning the detection of post-radiotherapy mucosal residual NPC using NBI system

MRI With Gadoxetate Disodium in Measuring Tumors in Patients With Liver Cancer
Adult Hepatocellular CarcinomaAdvanced Adult Hepatocellular Carcinoma7 moreThis pilot clinical trial studies magnetic resonance imaging (MRI) with gadoxetate disodium in measuring tumors in patients with liver cancer. Diagnostic procedures, such as MRI with gadoxetate disodium, may help find and diagnose liver cancer and find out how far the disease has spread. It is not yet known whether MRI with gadoxetate disodium provides a more precise measurement of liver tumors than standard computed tomography (CT).

Long Term Prospective Study Evaluating Effectiveness of Narrow Margins for Low-Risk Head and Neck...
Basal Cell CarcinomaThe purpose of this study is to determine the narrowest excision margin for head and neck Basal Cell Carcinoma (BCC) tumors satisfying the National Comprehensive Cancer Network® (NCCN) low-risk for recurrence clinical and histopathological criteria that gives an acceptable (95%) clinical cure-rate over a 3 year follow-up period. Margins of 1 and 2mm are evaluated.

Circulating Tumor Cells and Cytology in Cerebrospinal Fluid of Patients Clinically Suspected for...
Meningeal CarcinomatosisThe purpose of this study is to determine whether the quantitative detection of circulating tumor cells (CTCs) in patients with Epcam expressing tumors can be used compared to standard qualitative method - cytology both in the cerebrospinal fluid of patients, clinically suspected for leptomeningeal metastases.

Laparoscopic Versus Open Liver Resection in the Treatment of Hepatocellular Carcinoma
Hepatocellular CarcinomaThe purpose of this study is to investigate the clinical value of laparoscopic liver resection in the treatment of hepatocellular carcinoma by assessing its Surgical and oncologic outcomes comparing with open liver resection.

Non-comparative Study of Treatment With Induction Chemotherapy With Cisplatin and Gemcitabine Followed...
Patients Diagnosed With Advanced Carcinoma of Uterine Cervix tThe purpose of this phase II study is to determine the survival free disease of patients diagnosed with invasive locally advanced carcinomas of uterine cervix treated with induction chemotherapy with cisplatin and gemcitabine followed by chemoradiation and definitive chemoradiation.

Interest of Narrow Band Imaging in Detection of Upper Aerodigestive Cancers
Squamous Cell Carcinoma of OropharynxSquamous Cell Carcinoma of Hypopharynx1 moreThe aim of this study is to prospectively determine if the use of NBI endoscopy modifies the superficial extension of these tumors.

Effectiveness of Chemotherapy in Metastatic or Recurrent Carcinoma Cervix
Metastatic Carcinoma to the Uterine CervixRecurrent Carcinoma Cervix1 moreExperience with substituting carboplatin for cisplatin is limited in advanced and recurrent cervix cancer and there has been no counterpart to GOG 158, which documented therapeutic equivalency of cisplatin/paclitaxel and carboplatin/paclitaxel for treatment of ovarian cancer, performed in a cervix cancer population.

BIBF1120 in Patients With Advanced FGFR3 Mutated,Overexpressed,or Wild Type Urothelial Carcinoma...
Urothelial CarcinomaBIBF1120 in patients with advanced FGFR3 mutated, FGFR3 overexpressed, or FGFR3 wild type urothelial carcinoma of urinary bladder, urethra, ureter, and renal pelvis and who have failed platinum-based chemotherapy.

Intraoperative Imaging of Breast Cancer With Indocyanine Green
Invasive Ductal CarcinomaInvasive Lobular Carcinoma1 moreAccording to the World Health Organization, breast cancer is the most common cancer in women, and is responsible for 686,000 new cases every year. The WHO also posit that nearly 420,000 women perished from the disease in 2002. Surgery remains the best option for patients presenting with operable Stage I, II or III cancers. Breast conservation surgery has been shown to be as efficacious as mastectomy. About 60-70% of these women with operable breast cancer are breast conservation candidates. However, the need to achieve negative tumor margins often requires a second operation (re-excision) in up to 70% of the women having lumpectomy surgery. Currently, tumor margins assessment in the operating room is often assessed grossly by palpation. The ability to evaluate tumor margin using our proposed intraoperative imaging technique may provide the surgeon with an alternative, and hopefully, more sensitive method to assess tumor margins which may decrease re-excision and the morbidity associated with additional surgery, and, perhaps, lower the risk of local regional recurrence.