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Active clinical trials for "Carotid Stenosis"

Results 161-170 of 287

SPI-guided Analgesia During CEA Under RA

Carotid Artery Stenoses

The aim of this randomized prospective trial is to assess the utility of Adequacy of Anaesthesia technique (Response Entropy and Surgical Pleth Index) for monitoring pain perception intraoperatively, maintainance of hemodynamic stability during anesthesia and its influence on postoperative outcomes, in patients undergoing carotid endarterectomy under cervical plexus block.

Unknown status7 enrollment criteria

STAND: iSchemic sTroke evAluated at Bed Side With ultrasouND

Ischemic StrokeCarotid Stenosis

Ischemic strokes account for more than 80% of strokes. Ischemic strokes are caused by the occlusion of an intracranial artery by a thrombus, responsible for tissue ischemia related to a decrease in local cerebral blood flow (CBS). Thus, the management of patients with Ischemic strokes is based on the preservation of an area that maintains sufficient intracranial hemodynamics (IH) and achieves the fastest possible recanalization. The impact of the patient's position (supine or seated position) on the IH in the event of narrowing or occlusion of an artery is poorly assessed but may be of particular importance. In practice, variations in blood flow according to the positioning of the patient's body can be measured using a transcranial Doppler. It is a simple, non-invasive and painless examination that provides the patient's bed with data on the intracerebral hemodynamic profile of patients. This study was implemented because there are no studies known to us that evaluate the effect of verticalization on intracerebral hemodynamics based on the presence of upstream arterial stenosis or occlusion and other multimodal evaluation data in transcranial Doppler.

Terminated12 enrollment criteria

Transcranial Doppler(TCD) Evaluation of High Intensity Transient Signals and Carotid Disease

Asymptomatic Carotid StenosisSymptomatic Carotid Stenosis2 more

Carotid Disease causes 10% of strokes. The Investigators are attempting to investigate the use of Transcranial Doppler to see if this is and effective, efficient, and/or valid way to identify individuals at highest risk for thromboembolic events from carotid disease. The plan is to plot the number of high intensity transient transcranial doppler signals with the category of patient (asymptomatic, symptomatic, and actively symptomatic) and evaluate if a relationship exists. The Investigators hypothesize that a linear relationship exists in that the higher the number of HITS the more symptomatic the patient. If results demonstrate the numbers of HITS correlate with the severity of disease this could potentially identify asymptomatic patients having subclinical symptoms who would benefit from a more urgent surgical intervention versus the current standard of care of elective intervention.

Withdrawn3 enrollment criteria

Clopidogrel Resistance and Embolism in Carotid Artery Stenting

Carotid Stenosis

The purpose of this study is to evaluate the efficacy and safety of the ticlopidine + ginko biloba compared to clopidogrel in clopidogrel resistant patients undergoing carotid artery stent placement. The investigators hypothesized that ticlopidine + ginko biloba is superior than clopidogrel in terms of post-stent ischemic lesions in these patients without serious complications.

Unknown status7 enrollment criteria

Endarterectomy vs Stenting in Chinese Asymptomatic Carotid Stenosis Patients

Carotid Stenosis

Endarterectomy vs Stenting Asymptomatic Carotid stenosis patients to verify the efficacy and safety.

Unknown status36 enrollment criteria

Study on Vulnerable Plaque of Carotid Artery With Chinese Herbal and Insects Medicine

Carotid Artery Plaque

The investigators want treat Vulnerable plaque of carotid artery with a herbal and insects Chinese medicine. Designing a RCT trial to prove the effect and safety.

Unknown status11 enrollment criteria

A Prospective, Non-Randomized, Evaluation of Low-Risk Patients Undergoing Carotid Stenting With...

Carotid Stenosis

Prospective, non-randomized, single-center cohort study treating internal carotid artery stenosis using the Xact Carotid Artery Stent and emboshield distal protection system in conjunction with bivalirudin as the procedural anticoagulation

Unknown status23 enrollment criteria

Carotid Angioplasty and Stenting Versus Endarterectomy in Asymptomatic Subjects Who Are at Standard...

Carotid Artery DiseaseCarotid Stenosis2 more

The study is being conducted to demonstrate the non-inferiority of carotid artery stenting (CAS) using the Emboshield® Embolic Protection System with the Xact® Carotid Stent System to carotid endarterectomy (CEA) for the treatment of asymptomatic extracranial carotid atherosclerotic disease.

Terminated56 enrollment criteria

Insulin Resistance in Patients After Carotid Revascularization

Carotid Stenosis

The main purpose of this study is to study the phenomenon of insulin resistance in patients after carotid revascularization surgery through population-based, randomized, double-blind, placebo-controlled trial.

Unknown status10 enrollment criteria

Early Warning and Optimization Strategy in Carotid Endarterectomy

Carotid StenosisCarotid Artery Diseases2 more

Carotid endarterectomy has been proven effective in prevention of cerebral vascular events in patients with severe carotid artery stenosis (symptomatic,>50%;asymptomatic,60%). But during the surgery, when the carotid artery is clipping, the patient will have the chance to have hypoperfusion or stroke. Our study is designed to determine how to use TCD to reduce the risk of death and nonfatal stroke in patients .

Unknown status5 enrollment criteria
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