A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers
Amyotrophic Lateral SclerosisNervous System Diseases7 moreThe purpose of this study is to collect biofluid samples for the banking and usage in ALS research. Through comparison of these samples, the researchers hope to learn more about the underlying cause of ALS, as well as find unique biological markers, which could be used to develop new therapies.
Mobile Parkinson Observatory for Worldwide, Evidence-based Research (mPower)
Parkinson DiseaseNeurodegenerative Diseases5 moreThe purpose of this study is to understand variation in the symptoms of Parkinson disease. This study uses an iPhone app to record these symptoms through questionnaires and sensors.
The Long-Term Safety and Efficacy Follow-Up Study of Subjects Who Completed the Phase I Clinical...
Alzheimer DiseaseDementia10 moreThe purpose of the study is to determine the long-term safety and exploratory efficacy of NEUROSTEM®-AD, administered via an open brain surgery to subjects with dementia of the Alzheimer's type, who were eligible for and enrolled in the earlier part of the phase I. Aside from the subjects who completed the earlier part of the Phase I, 3 additional subjects with comparable demographics and disease characteristics as the treatment group will be enrolled into a control group, followed-up for 3 months, and compared for various disease progression indicators with the treatment group. The hypothesis is that NEUROSTEM®-AD is safe and effective in the treatment of dementia of the Alzheimer's type.
General Anesthesia for Endovascular Thrombectomy; A Pilot Study.
StrokeCerebrovascular Stroke7 moreThis study evaluates the outcomes of stroke patients treated for intravascular thrombectomy, using either a local anesthetic with sedation, or a general anesthetic. Historical data will be used for those treated with the local anesthetic, and prospective data will be used for those treated with the general anesthetic.
A Multicentre Clinical Investigation of a Decision Support Algorithm for Neonatal Seizure Detection...
SeizuresBrain Diseases4 moreThe ANSeR Clinical Investigation is a multi-centre, randomised, controlled, clinical investigation of a standalone decision support Algorithm for Neonatal Seizure Recognition, the ANSER Software system.
Neurosarcoidosis : Initial Presentation and Disease Course
NeurosarcoidosisNeurosarcoidosis represents up to 10% of sarcoidosis cases. Little is known about its long-term course, even if the disease remains mainly monophasic with/w.o. sequelae, or if bouts of new symptoms may arise over years (polyphasic). Using retrospective data from patients diagnosed with neurosarcoidosis in three French referral centers for neuro-inflammation, the investigators aim to determine patterns of disease course, according to the initial presentation and the treatments used.