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Active clinical trials for "Headache"

Results 1071-1078 of 1078

Does Topiramate Adjust the Excitability of the Brain in Migraine Sufferers?

MigraineChronic Headache

The purpose of the study is to determine by the use of non-invasive magnetic stimulation if the medication Topiramate adjusts the excitability of the migraine sufferer's brain. Previous studies have shown the migraine sufferer's brain is more excitable. The magnetic stimulation device has given us a way to look at excitability and to see if it changes at the same time that a headache diary shows if the pattern or severity of headaches changes with the administration of the drug Topiramate. It is expected that as migraine sufferers have fewer headaches with topiramate the testing with magnetic stimulation will show that their brains are less excitable and that if the topiramate does not change the character of headaches then the pattern of excitabilty would not change from the baseline test before medication is started.

Unknown status4 enrollment criteria

The Prognosis of Migraine and Tension-Type Headache in Children and Adolescents

ChildrenOnly4 more

Children and adolescents that visited the pediatric neurology clinic at the Bnai Zion medical center do to migraine or TTH headache between the years 2007-2010 were reevaluated. We used a structured headache questionnaire through a phone interview with the patients and their caregivers. Data regarding demographics, the patients' and families' medical history, and headache history, past and current (age at onset, location, quality, frequency, duration of episodes, aura, associated symptoms and treatment) were collected.

Unknown status3 enrollment criteria

Cortical Reorganisation in Patients With Primary Headache Disorders

Migraine Without AuraChronic Tension-Type Headache

Primary headache disorders are now accepted as physiological diseases, and advanced imaging-techniques have demonstrated a migraine generator in the brain stem and increased stimulus sensitivity in these patients. The underlying neuronal dysfunctions remain to to clarified and the existing neurophysiological methods have not yet been useful. More sensitive and reliable methods are therefore highly needed. The aims of the study are therefore to develop a sensitive and reliable method to demonstrate a cortical reorganisation and expansion of pain sensitive cortical areas in patients with migraine or tension-type headache.

Unknown status6 enrollment criteria

The Role of CGRPand Nociceptin in Migraine

MigraineHeadache

The release of the neuropeptide calcitonin gene-related peptide (CGRP) is thought to play a causative role in migraine. Nociceptin immunoreactivity and ORL-1 mRNA have been detected in human trigeminal ganglia where it was co-localized with CGRP. It may play a role in migraine pathogenesis. We are collecting the blood samples of migraineurs for analysis of these neuropeptides.

Unknown status1 enrollment criteria

Jaw Muscle Function in Patients With Tension-type Headache

Headache DisordersTension-Type Headache

Patients with tension-type headache (TTH) and migraine often experience musculoskeletal complaints, like neck pain and/or jaw pain. Earlier studies have revealed an association between different headache types and neck pain and discussed the possible role of the cervical muscles. Furthermore, patients with neck pain show a decrease in motor control of the jaw, without having any other signs of TMD. Similarly, studies in patients with TMD have only found an indication for poorer neck muscle function. Patients with TMD also show a decrease in bite force and force steadiness compared to healthy controls. It is however, unknown if bite force and force steadiness are similarly impaired in patients with headache and/or neck pain. The current study will take a closer look at the jaw muscle function of in patients with TTH, with and without neck pain.

Unknown status11 enrollment criteria

Postspinal Headache and Near Infrared Spectroscopy (NIRS)

Tissue Oxygenation

Evaluation of the relationship between postspinal headache and near infrared spectroscopy in cesarean section patients

Unknown status4 enrollment criteria

Primary Headaches and Irritable Bowel Syndrome.

Primary Headache Disorder

To assess the relationship between primary headaches and irritable bowel syndrome

Unknown status7 enrollment criteria

Prevalence of Post-craniotomy Headache in Siriraj Hospital

Adult Brain TumorHeadache

Headache after major craniotomy may be a problem in taking care of the patients. The investigators want to identify the incidence of headache after major craniotomy and also the risk factors.

Unknown status7 enrollment criteria
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