
Metoclopramide for Post Traumatic Headache
Post-Traumatic HeadacheNearly 1.5 million patients present to US emergency departments annually following head trauma. Headache is a frequent symptom of victims of head trauma. The purpose of this study is to see if an intravenous medication called metoclopramide can improve the symptoms of patients with acute post-traumatic headache.

Aerobic Exercise and Cognitive Training Effects on Postconcussive Symptomology
Post-Concussion SyndromePost-Traumatic Headache6 moreThe purpose of this study is to compare a 4-week, moderately intensive, lab and home-based aerobic exercise program versus exercise plus cognitive training. Participants will include individuals who experience lingering symptoms of a head injury or concussion.

Effectiveness of a Novel Device for Cervical Training in Cervicogenic Headache.
Cervicogenic HeadacheThe purpose of this study is to evaluate the clinical results in cervical spine range of motion, endurance deep cervical muscles, headache impact and physical activity enjoyment by a training protocol with the new device for cervical treatment (CDAT) versus conventional training protocol (CT) in subjects with cervicogenic headache.

Acupuncture for Headache Post-Traumatic Brain Injury: A Feasibility Study
Post-Traumatic HeadacheTraumatic Brain InjuryThis study evaluates and addresses challenges to implementing an acupuncture intervention for adults who have headaches after sustaining a moderate traumatic brain injury. Eligible participants will be recruited from Seattle and the surrounding areas to receive weekly acupuncture for 12 consecutive weeks. Participants will complete questionnaires to assess headache impact, depression, health-related quality of life, and cognitive function at the beginning of the study and every two weeks for the duration of the study. Participants will participate in structured interviews after the study for their views on the acceptability and tolerability of the study protocol.

Study of Gammacore Sapphire for the Acute and Preventive Treatment of Post-Traumatic Headache (GAP-PTH)...
Post-Traumatic HeadacheThe purpose of this single-center, prospective, randomized, double-blind, sham controlled, parallel-group study is to collect clinical data related to the safety and efficacy of vagus nerve stimulation for the acute and preventive treatment of Post Traumatic Headache.

Study of Rizatriptan in the Treatment of Acute Attacks of Post-traumatic Headache in U.S. Military...
Chronic Post-traumatic HeadacheThe purpose of the study is to determine the effectiveness of rizatriptan for treating attacks of chronic post-traumatic headache.

A Study to Test if Fremanezumab Reduces Headache in Participants With Posttraumatic Headache (PTH)...
Post-Traumatic HeadacheThis is a multicenter, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the safety and efficacy of fremanezumab in adult participants aged 18 to 70 years, inclusive, for the prevention of PTH. The study will include a double-blind (DB) treatment period (12 weeks) and an open-label (OL) treatment period (12 weeks).

Clinical Characteristics and Pathophysiology of Post-Traumatic Headache
Post-Traumatic HeadacheConcussion1 moreTo better understand the clinical characteristics and complex pathophysiological events that constitute persistent post-traumatic headache (PPTH) and to identify possible calcitonin gene-related peptide (CGRP) hypersensitivity in PPTH patients.

Effects of Workstation Ergonomics and Physiotherapy in Cervicogenic Headache.
Cervicogenic HeadacheCervicogenic headache (CgH) is a distinct form of headache and accounts for 17.8% of all headaches and the prevalence rate is between 0.4% and 20%. A guide to health and safety in the office handbook by common wealth of Australia (2008) suggested the ergonomic guidance and interventions for preventing and treating musculoskeletal disorder (MSD) injuries in the office workers. Also, It has been estimated that 34% of US citizens receive some sort of physiotherapy for CgH each year. However, no studies have compared and investigated the combined and individual effects of workstation ergonomics, physiotherapy and patient education for improving cervicogenic headache and work ability in office workers.

Nutrition for Post-Traumatic Headache
Post-Traumatic Headache Chronic Without Intractable HeadacheThe purpose of this multi-site study is to evaluate the efficacy of a high omega-3/low omega-6 dietary intervention (the H3-L6 Diet) vs. a Control Diet in reducing headache pain and improving function in soldiers, veterans and military healthcare beneficiaries with post-traumatic headache (PTH). In addition, the study will examine the effects of the diet interventions on anti-nociceptive and pro-nociceptive lipid mediators derived from omega-3 and omega-6 fatty acids.