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Active clinical trials for "Burns, Chemical"

Results 1-7 of 7

the Treatment of Human Bone Marrow Mesenchymal Stem Cells in Ocular Corneal Burn

Chemical Burns

Ocular chemical burn is one of the cause of vision loss in our country, and there are no satisfactory treatment. Human bone marrow mesenchymal stem cells (MSC) have the biological characteristics of self-renewal, immune regulation, multidirectional differentiation and tissue repair. Our preliminary research showed that in corneal alkali injury rats, the MSC can accelerated the cornea repair, inhibited angiogenesis. The aim of this study is to access the efficacy and safety of mesenchymal stem cell in the treatment of corneal burn in human.

Completed15 enrollment criteria

Safety and Performance Study of the ARGOS-IO System in Patients Undergoing Boston Keratoprosthesis...

Graft vs Host DiseaseCongenital Aniridia3 more

The ARGOS-IO pressure sensor is intended to be implanted in the human eye in combination with Boston Keratoprosthesis (BKPro) surgery and to remain in place indefinitely. It is intended to be used together with the hand-held Mesograph reading device to telemetrically measure the intraocular pressure (IOP) of patients with a BKPro. The purpose of this study is to evaluate the safety and performance of the ARGOS-IO system in patients undergoing concomitant implantation of a BKPro and an ARGOS-IO sensor over the 12 month period beginning at implantation.

Completed20 enrollment criteria

Minor Salivary Gland Transplantation for Cicatrizing Conjunctivitis

Cicatrizing ConjunctivitisStevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum4 more

This is a prospective study that aimed to observe the therapeutic effects of minor salivary gland transplantation for cicatrizing conjunctivitis patients.

Unknown status8 enrollment criteria

The Improvement of Limbal Epithelial Culture Technique by Using Collagenase to Isolate Limbal Stem...

Alkaline Chemical Burn Of Cornea And Conjunctival SacAcid Chemical Burn Of Cornea And Conjunctival Sac1 more

Using collagenase to isolate limbal stem cells and improve the technique of ex vivo expansion of limbal stem cells for the treatment of patients suffering from unilateral limbal stem cell insufficiency based on the concept of "limbal stem cells need special cell-cell contact and cell-extracellular matrix interaction to support their survival".

Unknown status20 enrollment criteria

Subconjunctival Injection of Allogeneic Mesenchymal Stem Cells in Severe Ocular Chemical Burn

Bone Marrow Donor

The objective of this pre-clinical study is to demonstrate the robustness of Bone Marrow derived Mesenchymal Stem Cells (BM-MSC) production, to treat patients with severe eye burns. For bone marrow donors who agree to participate, a 10 ml BM sample will be collected apart the 1 liter BM dedicated to transplantation. A maximum of three donors of allogeneic BM-MSCs will be included. A ready-to-use BM-MSC suspension will be produced and stored for 10 years to accumulate data about stability of cryopreserved cells.

Completed4 enrollment criteria

Clinical Trial on the Effect of Autologous Oral Mucosal Epithelial Sheet Transplantation

Limbal Stem Cell DeficiencyStevens-johnson Syndrome2 more

To investigate the effect of ocular surface reconstruction and assess the safety in cultivated oral mucosal epithelial cell sheet transplantation (COMET) regarding patients with cicatricial change of ocular surface.

Available12 enrollment criteria

The Postoperative Head Position as a Predictor of the Surgical Outcome After DMEK

Fuchs Endothelial Corneal DystrophyPseudophakic Bullous Keratopathy2 more

This study aims to investigate the influence of postoperative head position on clinical outcomes after DMEK via a wearable sensor.

Unknown status2 enrollment criteria
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