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Active clinical trials for "Chronic Urticaria"

Results 41-50 of 150

Chronic Urticaria - Long Term Assessment of Effects of Rupatadine

Chronic Urticaria

To compare CSU disease activity at the end of the follow up phase between patients that had been treated daily continuously vs. on-demand in the treatment phase

Terminated34 enrollment criteria

A Study of the Use of Methotrexate in the Treatment of Chronic Idiopathic Urticaria

Urticaria

The purpose of this study is to determine whether methotrexate produces significant improvement in chronic idiopathic urticaria, compared with placebo

Terminated7 enrollment criteria

Efficacy of Rupatadine 5, 10 and 20 mg in Chronic Idiopathic Urticaria

URTICARIA

The objective of this study is to evaluate the efficacy and safety of rupatadine for the treatment of CIU symptoms.To assess the clinical efficacy of a dose ranging of rupatadine fumarate (5mg, 10mg, and 20 mg) compared with placebo for relief of CIU symptoms.

Terminated26 enrollment criteria

Efficacy and Safety of Rupatadine 10 and 20 Mg in Chronic Idiopathic Urticaria

Urticaria

· To evaluate the efficacy of rupatadine 10 and 20 mg for the treatment of CIU symptoms over four-week treatment period in comparison with placebo.

Terminated26 enrollment criteria

A Real-world Study to Assess Safety and Effectiveness of Xolair® in Pediatric Chronic Spontaneous...

Chronic Spontaneous Urticaria

This non-interventional, multi-center, prospective post-approval study aims to provide safety and effectiveness data of Xolair® in Chinese adolescents with Chronic Spontaneous Urticaria who remain symptomatic despite H1 antihistamine treatment. The study period is 16 weeks which contains a 12-week treatment period and 4-week safety follow-up.

Not yet recruiting11 enrollment criteria

Bilastine Updosing in Chronic Spontaneous Urticaria

Chronic Urticaria

Chronic spontaneous urticaria (CSU), formerly also known as chronic idiopathic urticaria and chronic urticaria (CU), is one of the most frequent skin diseases. At any time, 0.5-1% of the population suffers from the disease. Although all age groups can be affected, the peak incidence is seen between 20 and 40 years of age. The duration of the disease is generally several years but is likely to be longer in more severe cases, cases with concurrent angioedema, in combination with physical urticaria or with a positive autologous serum skin test (autoreactivity). CSU has major detrimental effects on quality of life, with sleep deprivation and psychiatric comorbidity being frequent. It also has a large impact on society in terms of direct and indirect health care costs as well as reduced performance at work and in private life.

Completed27 enrollment criteria

An Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of LOU064 in Subjects...

Chronic Spontaneous Urticaria

The main objective to assess the long-term safety and tolerability of LOU064 in patients with chronic spontaneous urticaria (CSU) who have participated in study CLOU064A2201 (NCT03926611)

Completed19 enrollment criteria

A Phase III Study of Efficacy and Safety of Ligelizumab in the Treatment of CSU in Adolescents and...

Chronic Spontaneous Urticaria

The purpose of this study was to establish efficacy and safety of ligelizumab in adolescent and adult subjects with CSU who remained symptomatic despite standard of care treatment by demonstrating better efficacy over omalizumab and over placebo. The study population consisted of 1,079 male and female subjects aged ≥ 12 years who were diagnosed with CSU and who remained symptomatic despite the use of H1-antihistamines. This was a multi-center, randomized, double-blind, active- and placebo-controlled, parallel-group study. There was a screening period of up to 28 days, a 52 week double-blind treatment period, and a 12 week post-treatment follow-up period.

Completed17 enrollment criteria

A Comparative Double-Blind, Double- Dummy Study of Desloratadine (DL) 5 MG Once Daily, Cetirizine...

Urticaria

This was a randomized, double-blind, parallel-group, multicenter study that used both an active control (cetirizine) and a placebo control to evaluate desloratadine 5 mg once daily during a 28-day treatment period. The active treatments and placebo were allocated in a 2:2:1 ratio.

Completed24 enrollment criteria

Safety Study of Levocetirizine Dihydrochloride Oral Liquid Formulation in Children Aged 1 to Less...

Allergic RhinitisChronic Urticaria

The purpose of this study is to determine the safety of the oral formulation of levocetirizine in children ages 1 to less than 6 years old who suffer from allergic rhinitis or chronic urticaria of unknown origin.

Completed23 enrollment criteria
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