The Efficacy of CBT-I in Alcoholics & Its Effects on Remission & Relapse
InsomniaInsomnia is a highly prevalent disorder in those recovering from alcoholism. It has been associated with anxiety and depressive symptoms, as well as an increased risk of relapse back to the drinking. Cognitive Behavioral Therapy for Insomnia (CBT-I), a non-pharmacologic approach is the recommended standard of care for insomnia. Some preliminary studies have shown that CBT-I may be efficacious for insomnia during recovery. The current study proposes to use a standard 8-week CBT-I to treat the insomnia with a post-treatment follow-up at 3- and 6-months (after treatment). Further, it will evaluate if an improvement in the insomnia is associated with an improvement in the underling alcoholism and the daytime functioning. On an exploratory basis, the association of a first-degree family history of alcoholism with the insomnia severity and treatment response will also be evaluated.
Helping Young Children Sleep
InsomniaThe investigators are conducting a randomized trial of behavioral treatments for young children with insomnia. The investigators are comparing the improvement in sleep patterns after families are given access to Internet sleep instructions compared to DVD sleep instructions.
Comparison of Two Temperatures to Treat Insomnia
Primary InsomniaInsomnia patients demonstrate subjective and physiological hyperarousal. The Cereve Sleep System has been proposed as a clinical treatment to reverse this hyperarousal in insomnia patients. The current study is a two dose study to determine the optimal temperature for the Cereve Sleep System. Primary outcome measures include EEG sleep measured sleep latency and sleep efficiency.
Feasibility of Non-pharmacological Insomnia Therapy in People Living With HIV
InsomniaSleep EfficiencyTo establish with a prospective randomized placebo-controlled study the feasibility of allied-health personnel-administered cognitive behavioral insomnia therapy (CBTI) as a means of improving HIV/AIDS treatment adherence.
Sleep to Lower Elevated Blood Pressure
HypertensionSleep Disorders2 moreSleep is an essential component of good physical and mental health. Previous studies have reported that poor quality sleep is associated with an increased risk of hypertension, stroke and cardiovascular disease (CVD). Hypertension is the most common and important risk factor for CVD, and even modest reductions in blood pressure result in significant reductions in stroke and myocardial infarction. In this randomised trial, the investigators aim to evaluate whether a simple, multi-component, online sleep intervention reduces blood pressure in patients with essential hypertension.
Non-pharmacological Treatment of Insomnia in Nursing Homes.
InsomniaThe study wants to examine the feasibility of a non-pharmacological approach for insomnia in nursing homes provided by trained nurses/paramedics and physicians.
Efficacy and Safety of Ramelteon on Chronic Insomnia
Chronic InsomniaThe purpose of this study is to determine the dose response of Ramelteon, once daily (QD), in Japanese subjects with Chronic Insomnia
Facilitation of Zolpidem (≥10 mg) Discontinuation Through Use of Ramelteon in Subjects With Chronic...
Chronic InsomniaThe purpose of this study is to assess whether ramelteon, once daily (QD), can facilitate the discontinuation of zolpidem in subjects with chronic insomnia.
Combined Behavioral/Pharmacological Therapy for Insomnia
Sleep Initiation and Maintenance DisordersThis study will determine how sleeping pills can be combined with nondrug treatments to maximize the benefits of therapy for insomnia.
Clinical Benefit of CBT for Insomnia in Primary Care
InsomniaThe purpose of this study is to evaluate using an RCT the potential benefits of CBT for insomnia in the community