An International Trial to Evaluate the Efficacy and Safety of SABER®-Bupivacaine for Postoperative...
Postoperative PainThe objective is to identify the optimal dose of SABER-Bupivacaine for postoperative pain control in patients undergoing hysterectomy on the basis of pharmacokinetics, efficacy and safety evaluations. The study duration consists of a screening period up to 14 days and a treatment period 14 days with a long term follow up visit at 6 months. The study will provide further data on the efficacy and safety of the product.
A Study to Compare Patient-controlled Pain Medications Delivered Either Through the Skin or Intravenously...
PainAnalgesia3 moreThe purpose of this study is to evaluate the effectiveness and safety of a patient-controlled system to deliver fentanyl compared with a patient-controlled intravenous system to deliver morphine in the management of postoperative pain.
To Evaluate the Safety, Tolerability and Analgesic Efficacy of SAF312 in Postoperative Dental Pain...
Postoperative PainThe study will assess the analgesic efficacy and safety and tolerability of a single oral dose of SAF312 in postoperative dental pain patients after 3rd molar extraction.
Postoperative Pain After Volar Plating for Distal Radius Fractures
Distal Radius FracturesThe investigators undertook to evaluate early postoperative pain levels after the volar plating of distal radius fractures performed under regional anesthesia, and to determine whether periarticular multimodal drug injections into the joint, ligament, periosteum, subcutaneous tissue, and skin, and into interosseous and superficial radial nerves (as an additional sensory nerve block) provide additional pain management benefits.
Comparison of the Efficacy and Safety of Q8003 Versus Its Individual Components in Bunionectomy...
Moderate to Severe Postoperative PainThis is a randomized, double-blind, multicenter, fixed dose factorial study of Q8003 12 mg/8 mg versus its individual morphine sulfate and oxycodone hydrochloride components for the management of acute moderate to severe postoperative pain following bunionectomy surgery.
A Comparison of Naropin and Ketorolac for Postoperative Analgesia After Total Knee Arthroplasty...
Postoperative PainThe purpose of this study is to determine wether ketorolac is effective in the treatment of postoperative pain after total knee arthroplasty
Local Infiltration Analgesia With Ropivacaine Versus Placebo in Bilateral Knee Arthroplasty
Postoperative PainThe purpose of this study is to examine whether local infiltration analgesia (LIA) with Ropivacaine and adrenaline is effective in the treatment of postoperative pain after total knee arthroplasty.
Cesarean Delivery and Post-operative Pain Management With Local Anesthesia
PainPostoperativeThe use of .5% Bupivacaine with epinephrine at the time of skin closure in cesarean deliveries will decrease post-op pain.
Comparison of Side Effects of Morphine and Hydromorphone Patient-Controlled Analgesia (PCA)
Post Operative PainBoth morphine and hydromorphone are pain medications commonly used after surgery. It is thought at the institution that hydromorphone causes less side effects but this has not been studied. The study proposes to treat the patients with either morphine or hydromorphone and determine how much nausea, vomiting, and itching they have with each drug
Celecoxib for Reducing Morphine Requirement After Thyroid Surgery: A Randomized Controlled Trial...
Postoperative PainThyroidectomy1 moreThe purpose of this study is to determine whether celecoxib is effective in the treatment postoperative pain after thyroidectomy. The research hypothesis: There is a difference in postoperative morphine consumption in the first 24 hours after thyroidectomy between patients who received celecoxib or placebo.