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Active clinical trials for "Migraine with Aura"

Results 41-50 of 91

A Phase I Study to Study the PK and Safety of Single Doses of STS101, DHE Injection and Nasal Spray...

Migraine With AuraMigraine Without Aura1 more

Single-center, single-dose, open-label, 2-part, 3-period crossover (in each part), pharmacokinetic and safety study.

Completed6 enrollment criteria

Digital Treatment for Migraines - a Feasibility Study

Migraine With AuraMigraine Without Aura

An individualised internet-based treatment from a biopsychosocial perspective for patients with migraines in primary care has been developed within the Vastra Gotaland region in 2019. The treatment program is called Learning to live with migraines, and goes by the acronym "I am" (Internet Approach to Migraine). In a pilot study, the treatment programme and its feasibility in primary care will be evaluated. It is hoped that the intervention "I am" can educate patients about their illness and help the patient manage migraine attacks so that the likelihood of difficulty and frequency of migraine attacks does not increase, as well as provide an increased function and quality of life.

Completed14 enrollment criteria

PRIMA PFO Migraine Trial

MigraineMigraine With Aura2 more

The purpose of this study is to evaluate migraine headache frequency in subjects who have migraine with aura and a patent foramen ovale (PFO, a slit-like opening between the right and left upper chambers (atria) of the heart which normally closes at or soon after birth) who are randomized to either undergo closure of the patent foramen ovale or continue with standard medical management.

Terminated6 enrollment criteria

Study With Migraid Device in Acute, Early Treatment of Migraine With Typical Aura

Migraine With Typical Aura

The purpose of the study was to assess the efficacy of Migraid in terms of preventing headaches in patients with migraine with typical aura. The secondary objectives were to assess whether Migraid is able to achieve pain relief and/or relief of migraine associated symptoms and to evaluate the safety and tolerability of the study treatment.

Completed23 enrollment criteria

Mindfulness for Adolescents for CM and HFEM

Migraine in ChildrenMigraine With Aura

Chronic Migraine (CM) and High Frequency Episodic Migraine (HFEM) without Aura affect adolescents' lives in terms of reduced health, reduced ability to perform daily chores and reduced quality of life. The use of pharmacological prophylaxis in these patients warrants caution, whereas the use of behavioral treatments is gaining support in literature. The main aim of MINDKIDS trial is to test the effect of a seven weekly group sessions of guided mindfulness-based meditation program on 12-month headache frequency reduction, medications intake, disability, anxiety, depression, catastrophizing, and caregivers' burden. This is a single-arm study. All patients will participate to seven weekly guided sessions (60 minutes each) of guided mindfulness meditation, which is aimed to teach and make direct practice with skills intended to enhance sustained, non-judgmental present moment awareness. The intervention's main topics are: posture education; breath use and control; guided body scan; work with sounds; tension release; guided imagery; decentralization of thoughts. Each session is conducted by a neurologist and a psychologist expert in mindfulness practice. During the sessions, patients are asked to close their eyes and focus their attention on the breathing so that they can concentrate on the present moment and on all the sensations. Patients were educated to promote a healthy lifestyle: regular physical activity, avoiding skipping meals, hydration, maintain a regular sleep/wake pattern at least 7-8 hours per night.

Completed9 enrollment criteria

Candesartan Versus Propranolol for Migraine Prevention

Migraine Without AuraMigraine With Aura1 more

The main aim of the present study is to compare candesartan with propranolol for migraine prophylaxis.

Completed23 enrollment criteria

Efficacy and Safety of Oral Sumatriptan Plus Oral Promethazine in Migraine Treatment

Migraine With AuraMigraine Without Aura

The purpose of this study is to show the efficacy of promethazine in management of patients with moderate to severe migraine

Completed11 enrollment criteria

A Study of the Efficacy and Safety of Two Doses of Topiramate Compared to Placebo and Propranolol...

MigraineCommon Migraine2 more

The purpose of this study is to evaluate the safety and efficacy of two doses of topiramate (100 and 200 mg daily) versus placebo and propranolol in the prevention of migraine. The study will also assess dose response relationship of topiramate, estimate the relative efficacy of topiramate versus propranolol in prevention of migraine, and evaluate the effect of migraine prevention with topiramate versus placebo on Health Related Quality of Life.

Completed9 enrollment criteria

Evaluation of the Effectiveness of Topiramate in Preventing the Transformation From Episodic Migraine...

MigraineHeadache2 more

The purpose of this study is to determine whether Topiramate is effective in preventing the development of chronic daily headache among patients with episodic migraine headaches.

Completed12 enrollment criteria

Study to Evaluate the Efficacy and Safety of Dronabinol Metered Dose Inhaler (MDI) in Acute Treatment...

Migraine With AuraMigraine Without Aura

The primary objective of this study is to evaluate the efficacy and safety of dronabinol MDI for the acute treatment of moderate to severe migraine headache.

Completed2 enrollment criteria
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