
Reserpine for the Treatment of Cocaine Dependence - 1
Cocaine-Related DisordersSubstance-Related DisordersThe purpose of this study is to assess the efficacy and safety of reserpine for the treatment of cocaine dependence.

Cocaethylene as a Treatment for Cocaine Dependence - 1
Cocaine-Related DisordersCocaine has been cited as the primary drug threat in the United States. The purpose of this study is to determine if cocaethylene, used as a prototype drug, is a safe and effective treatment for cocaine dependence.

Tiagabine for the Treatment of Cocaine Dependence - 1
Cocaine-Related DisordersThe purpose of this study is to assess tiagabine for the treatment of cocaine dependence.

Psychostimulant Abuse - Novel Treatment Approaches - 1
Cocaine-Related DisordersTo determine if acute assessments of profasi and factrel affect plasma cocaine levels and cocaine-induced behavioral changes in men.

Carbamazepine Treatment of Cocaine Dependence - 1
Cocaine-Related DisordersSubstance-Related DisordersThe purpose of this study is to compare the efficacy of carbamazepine in treatment of cocaine-dependence in patients with affective disorders.

Evaluation of a Desipramine Ceiling in Cocaine Abuse - 1
Cocaine-Related DisordersSubstance-Related DisordersThe purpose of this study is to confirm whether a blood level ""ceiling"" exists on desipramine effect in cocaine abuse.

Mazindol for Cocaine Abuse - 2
Cocaine-Related DisordersThe purpose of this study is to evaluate high and low dose mazindol for cocaine abuse.

Glutaminergic Agents for Cocaine Abuse - 5
Cocaine-Related DisordersThe purpose of this study is to evaluate glutaminergic agents for cocaine abuse.

Effects of Nefazodone on Treatment of Female Cocaine Abusers - 3
Cocaine-Related DisordersThe purpose of this study is to determine the effects of nefazedone on cocaine self-administration in depressed and non-depressed female cocaine users.

Alterations in Serotonergic Functions in Cocaine Addicts - 1
Cocaine-Related DisordersThe purpose of this study is to evaluate alterations in the serotonergic system in cocaine addicts and attempt to dissociate changes secondary to cocaine use from those associated with premorbid characteristics.