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Active clinical trials for "Cocaine-Related Disorders"

Results 361-370 of 407

Computerized Exercise to Alter Stimulant Approach Responses

Amphetamine-Related DisordersCocaine-Related Disorders1 more

The purpose of this study is to evaluate the Computerized Exercise to Alter Stimulant Approach Responses (CEASAR), a novel stimulant use cessation intervention, for clients currently enrolled in a treatment centre for mental health and addiction. The investigators plan to conduct a randomized, single-blind controlled trial involving inpatients presenting with concurrent disorders to test the impact of this novel computerized intervention. This pilot study will be conducted at the Burnaby Centre for Mental Health and Addiction (BCMHA) in Burnaby, BC, Canada.

Unknown status5 enrollment criteria

Drug Interaction Study With NS2359 and Cocaine in Cocaine Experienced Volunteers - 1

Cocaine-Related DisordersDrug Administration Schedule2 more

The purpose of this study is to conduct a drug interaction study with NS2359 and cocaine in cocaine experienced volunteers.

Unknown status2 enrollment criteria

Assessment of the Potential Interactions Between Cocaine and GBR 12909 - 1

Cocaine-Related Disorders

The purpose of this study is to assess the potential interactions between iv cocaine and GBR 12909.

Unknown status3 enrollment criteria

Cocaine in Parotid Saliva, Blood and Urine - 4

Cocaine-Related Disorders

The purpose of this study is to establish the use of parotid saliva as a means of detecting and quantifying cocaine and its metabolites.

Completed1 enrollment criteria

Effects of Repeated Transcranial Magnetic Stimulation (rTMS) on the Treatment of Cocaine Addicted...

Cocaine AddictionTreatment1 more

Cocaine addiction is a serious disease. Nowadays we still have no efficient method reducing craving and extending the abstinence period of this patients during treatment. The aim of this study is to evaluate reduction if craving and other parameters related to addiction within this group of patients through a treatment with transcranial magnetic stimulation.

Unknown status9 enrollment criteria

Methylphenidate Raclopride Positron Emission Tomography (PET) Test - 11

Cocaine-Related DisordersSubstance-Related Disorders

The purpose of this study is to evaluate PET methodology to study in vivo synaptic dopamine release.

Completed2 enrollment criteria

Glutamate-Glutamine Cycling (VCYC) During Cocaine Abstinence Using 1H-MRS

Cocaine DependenceHealthy

This study is designed to look at the relationship between brain glucose utilization, neurotransmission (e.g., glutamate, also known as the main excitatory amino-acid neurotransmitter in the brain), and synaptic density. This relationship will be explored in the brain's prefrontal cortex, an area important in decision-making and impulsivity.

Completed18 enrollment criteria

Pathophysiological Subtyping of Abnormalities in Cocaine Dependence - 9

Cocaine-Related DisordersSubstance-Related Disorders

The purpose of this study is to define pathophysiological subtypes of abnormalities in subjects with cocaine dependence.

Completed1 enrollment criteria

Evaluation of Modafinil as a Cocaine Treatment Medication and Interactions With Cocaine - 1

Cocaine-Related DisordersDrug Administration Schedule2 more

The purpose of this study is to evaluate modafinil, a cocaine treatment medication, and its interactions with intravenous (IV) cocaine.

Unknown status2 enrollment criteria

Cocaine Use Disorder and Cortical Dopamine

Cocaine Dependence

The goal of this study is to use [C-11]FLB 457 and amphetamine (oral, 0.5 mg/kg) to measure cortical dopamine transmission in cocaine dependent individuals and healthy controls

Completed16 enrollment criteria
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