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Active clinical trials for "Cognition Disorders"

Results 331-340 of 347

Guidance for Elderly With Cognitive Disorders

Mild Dementia

The purpose of the programme is to facilitate the anticipation of dementia both in elderly patients suffering from this disease and in their carers and to diminish care burden in order to improve quality of life and daily functioning.

Completed1 enrollment criteria

Establishment of a Bank of Biospecimens for Future Research on Age-related Cognitive Disorders

DementiaAlzheimers Disease

This study is collecting tissue specimens (blood, urine and saliva) from up to 1000 patients, with and without cognitive disorders, to store in the Bio Bank for future research. The specimens could be used in future research projects that could help improve the accuracy of diagnosis of a disease, predict who might develop a disease, help monitor the disease, or improve the understanding of the disease. Patients are only being recruited from Beaumont Hospitals Geriatric Clinic.

Completed7 enrollment criteria

Neural Mechanisms of Motor and Cognitive Networks

Normal VolunteersCognition Disorders1 more

This study investigates the neural mechanisms of motor and cognitive networks using cognitive assessment, reaction time measurement, high-density EEG and fMRI.

Completed10 enrollment criteria

Schizophrenia Cognition Scale Development

SchizophreniaCognition Disorders

The objective of this protocol is to develop items for a patient-reported outcome (PRO) measure to assess the patient's perspective and subjective experience of cognitive impairment associated with schizophrenia (CIAS).

Completed18 enrollment criteria

Assessing Cognitive Performance Among Adults With Attention Disorders Working on Treadmill

Attention Deficit Disorder

Randomized clinical trial in which individuals who have been diagnosed with ADHD and are regularly treated with Methylphenidate will be test for cognitive performance and will be randomly examined in the following four conditions: While taking Methylphenidate and sitting at a desk While taking Methylphenidate and walking on a treadmill workstation Without taking Methylphenidate while sitting at a desk Without taking Methylphenidate while walking on a treadmill workstation The investigators will compare the cognitive achievements outcomes and evaluate the efficiency of studying in each of these four conditions.

Unknown status7 enrollment criteria

The Long-Term Safety and Efficacy Follow-Up Study of Subjects Who Completed the Phase I Clinical...

Alzheimer DiseaseDementia10 more

The purpose of the study is to determine the long-term safety and exploratory efficacy of NEUROSTEM®-AD, administered via an open brain surgery to subjects with dementia of the Alzheimer's type, who were eligible for and enrolled in the earlier part of the phase I. Aside from the subjects who completed the earlier part of the Phase I, 3 additional subjects with comparable demographics and disease characteristics as the treatment group will be enrolled into a control group, followed-up for 3 months, and compared for various disease progression indicators with the treatment group. The hypothesis is that NEUROSTEM®-AD is safe and effective in the treatment of dementia of the Alzheimer's type.

Unknown status30 enrollment criteria

Well-Being in Medical Residents in the HIBA

Cognition DisordersDepression2 more

It is necessary and important to design tools to evaluate a central aspect of medical residents formation. The research group has been working with resident well-being since a few years in order to improve the global quality of the education and working environment. The investigators present a plan to develop and validate a tool to assess residents well-being. A tool designed with this characteristics would be of much importance to monitored as a security event, managed and actively promoted well being in residents.

Unknown status2 enrollment criteria

Postanesthesia Cognitive Recovery and Neuropsychologic Complications

Anesthesia Recovery PeriodDelirium4 more

The study proposes to analyze the difference in the rapidity of the recovery of post operative cognition immediately after extubation and 20, 40 and 60 minutes post extubation and neuropsychological complications (delirium) after 48 hours following general anesthesia using a prospective, randomized approach. Patients undergoing any type of surgery with the exception of cranial, cardiac or thoracic surgery can be enrolled in the study.

Unknown status3 enrollment criteria

Assessing Cognitive fUnction and MEasuring the Cerebral circulatioN on HaemoDialysis

End-Stage Renal DiseaseStroke1 more

Stroke disease and cognitive impairment are common in patients established on haemodialysis (HD) for end-stage renal disease (ESRD). Further, initiation of HD appears to transiently increase the risk of stroke. The mechanism by which this occurs is not known. Using ultrasound, patient questionnaires and brain MRI our study will observe changes in cognition and cerebral blood flow whilst receiving HD compared to a non-dialysis day. Transient clinical and ultrasound alterations will be correlated to radiographic changes in cerebral perfusion and structure on MRI to determine the underlying mechanism for the increased stroke risk. The investigators will observe this effect in the immediate and longer term (12 months observation). A greater understanding will allow development of effective preventive strategies.

Unknown status7 enrollment criteria

Chemotherapy-induced Cognitive Alterations in Recruits With Ovarian and Breast Cancer

Cognition DisordersPolyneuropathies

Neurotoxic phenomena are among the most common and difficult to treat side effects of chemotherapy. The development of chemotherapy induced peripheral neuropathy (CIPN) is a well-recognized adverse reaction in the peripheral nervous system. Side effects of chemotherapy in the central nervous system, however, particularly changes of cognitive function (in non-medical literature referred to as "chemobrain") are diffuse and difficult to attribute to individual cytostatic drugs. The primary purpose of this study is to assess cognitive function in patients with ovarian and breast cancer before and after systemic chemotherapy with paclitaxel with standardized neuropsychological tests and compare the outcome to patients with benign gynecological tumors and breast cancer without chemotherapy treatment, respectively. Secondary parameters include the assessment of olfactory function, total neuropathy score and cytokine profiles.

Unknown status10 enrollment criteria
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