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Active clinical trials for "Common Bile Duct Neoplasms"

Results 1-5 of 5

Effects of Dexamethasone on Common Bile Duct Cannulation Time

Common Bile Duct DiseasesCommon Bile Duct Calculi3 more

The main aim of this clinical trial is to evaluate the effects of dexamethasone on common bile duct cannulation time during endoscopic retrograde cholangiopancreatography (ERCP) in patients with biliary pathologies. The study will also study the effects of dexamethasone on total procedure time and total fluoroscopy time during ERCP. Participants will be divided into two groups, treatment group and placebo group. Patients in treatment group will receive dexamethasone and those in placebo group will be given normal saline before undergoing ERCP. The results in both groups will be compared to determine the effects of dexamethasone.

Not yet recruiting11 enrollment criteria

Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma

Hilar CholangiocarcinomaIntrahepatic Cholangiocarcinoma3 more

The goal of this observational cohort study is to assess the yield of preoperative endoscopic ultrasound focussed on lymph nodes in patients with presumed resectable perihilar (pCCA), intrahepatic (iCCA) or mid-common bile duct (CBD) cholangiocarcinoma. The main questions it aims to answer is: The number of patients precluded from surgical work-up due to positive regional or extraregional lymph nodes identified by endoscopic ultrasound guided tissue acquisition Characteristics during endoscopic ultrasound of lymph nodes associated with malignancy

Recruiting10 enrollment criteria

Prospective Multicenter Evaluation of a New Short-access-cholangioscope for Biliary Duct Strictures...

CholedocholithiasisCommon Bile Duct Neoplasms1 more

Karl Storz GmbH (Gesellschaft mit beschränkter Haftung) company developed a cholangioscopic device, which is designed to give a better flexibility to the cholangioscopy tip in order to enable optimal diagnostic and therapeutic precondition. Other than the conventional mother-baby technique, the insertion of the cholangioscope (baby part) is done by a port at the side of a specially developed duodenoscope (mother part) which is prepositioned distally to the control unit, near to the patient's mouth. Better manoeuverability of the device tip will lead to both a better accuracy in taking biopsies as well as a better flexibility in lithotripsy manoeuvres. This study is designed to test the efficiency of the device in relation to this assumption.

Completed7 enrollment criteria

Pancreaticoduodenectomy With or Without Preoperative Hyperbaric Oxygen Therapy

Periampullary TumorCommon Bile Duct Neoplasms1 more

The primary objective of this study is to assess the safety, tolerability and toxicity of preoperative HBOT in patients undergoing a pancreaticoduodenal resection for premalignant and malignant tumors of the common bile duct, periampullary and duodenum.

Unknown status20 enrollment criteria

Artificial Intelligence for Digital Cholangioscopy Neoplasia Diagnosis

Common Bile Duct NeoplasmsNon-Neoplastic Bile Duct Disorder

Digital single-operator cholangioscopy (DSOC) findings achieve high diagnostic accuracy for neoplastic bile duct lesions. To date, there is not a universally accepted DSOC classification. Endoscopists' Intra and interobserver agreements vary widely. Cholangiocarcinoma (CCA) assessment through artificial intelligence (AI) tools is almost exclusively for intrahepatic CCA (iCCA). Therefore, more AI tools are necessary for assessing extrahepatic neoplastic bile duct lesions. In Ecuador, the investigators have recently proposed an AI model to classify bile duct lesions during real-time DSOC, which accurately detected malignancy patterns. This research pursues a clinical validation of our AI model for distinguishing between neoplastic and non-neoplastic bile duct lesions, compared with high DSOC experienced endoscopists.

Completed7 enrollment criteria
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