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Active clinical trials for "Communicable Diseases"

Results 4521-4530 of 4534

Day Zero Urinary Catheter Removal in Gen Thoracic Surgery Patients

Postoperative Retention of UrinePostoperative Urinary Tract Infection

Current standard of practice in study institution dictates day of surgery urinary catheter removal in general thoracic surgery patients receiving thoracic epidural analgesia. The investigators hypothesize that this practice results in low recatheterization rates secondary to urinary retention and low urinary tract infection rates.

Unknown status8 enrollment criteria

The Role of Cathepsin X in Infection With the Helicobacter Pylori

Persistence of Infection With Helicobacter Pylori

The immune response to Helicobacter pylori (Hp) importantly determines the pathogenesis of infection as well as the success of antibiotic eradication of the bacteria. The investigators want to demonstrate the importance of cathepsin X (CTSX), a cysteine protease, for the Hp eradication success. The diversity of the innate immune response to H. pylori antigens leading to either successful eradication of the infection or maintenance of chronic inflammation is connected to CTSX. The aim of this study is to determine whether H. pylori suppresses the CTSX expression and cytokine secretion in macrophage cell line THP-1 in the individuals that are not capable of eradicating the infection, opposite to H pylori in patients with successful H pylori eradication . The investigators also investigate the possibility whether strain-dependent differences in H. pylori lipopolysaccharide (LPS) influence the CTSX expression and cytokine secretion.

Unknown status1 enrollment criteria

NETs Formation in Patients With Recurrent Pyogenic Infections (NETS)

Pyogenic Infections

We aim to study if pathological NETs formation could be the underlying pathology among patients with recurrent infections and a normal screening of the immune system.

Unknown status3 enrollment criteria

Antibiotic Resistant Bacteria Among Patients With Severe Intraabdominal Infections

Complicated Intra-Abdominal Infections

The objectives of the study were: To study risk factors for colonization and infection with antibiotic resistant bacteria among patients with severe IAI before and after antibiotic treatment and surgical intervention. To study species changes in the rectal flora among patients with severe IAI before and after antibiotic treatment and surgical intervention. To review guidelines for antibiotic use in participating units. To evaluate surgical antibiotic prophylaxis and treatment in relation to risk for colonization and infection with antibiotic resistant bacteria among patients with severe IAI To use the results from the study in the process of a more appropriate use of antibiotics in participating units and care of patients with severe IAI. To study the dynamics of extended-spectrum beta-lactamase producing and wild-type Enterobacteriaceae in patients with suspected severe intra abdominal infections before, during and after antibiotic treatment.

Unknown status3 enrollment criteria

Multicenter Trial of Daily Chlorhexidine Bathing to Reduce Nosocomial Infections

Nosocomial BacteremiaMRSA Colonization3 more

To determine if daily bathing with chlorhexidine impregnated washcloths will reduce the incidence of MRSA and VRE within an Intensive Care Unit (ICU) or ward setting.

Unknown status6 enrollment criteria

Biomarkers in Infection

SepsisInfection1 more

The purpose of this investigation is to evaluate how early biomarkers of infection and inflammation perform in identifying patients at risk for poor outcome in sepsis and septic shock.

Unknown status9 enrollment criteria

Potential Adverse Developmental and Nutritional Consequences of Helicobacter Pylori Infection in...

Helicobacter Pylori InfectionIron Deficiency Anemia1 more

The investigators believe that there is an association between H. pylori infection and nutritional status and between H. pylori infection and cognitive development. The current study will examine this association in Israeli children, aged 6-12 years.

Unknown status5 enrollment criteria

DNA-based Testing in BAL of Lung Transplant Recipients With Suspected Non-viral Lower Respiratory...

Lower Respiratory Tract and Lung Infections

Lung transplantation (LTx) , DNA-based testing. Performance of DNA-based testing of bacterial and fungal pathogens in comparison to standard testing. Experimental intervention: DNA-based testing of BAL fluid.

Unknown status10 enrollment criteria

Vancomycin Versus Ceftaroline in Patients With Infections Caused by MRSA That Are Susceptible to...

MRSA InfectionBacteremia2 more

To compare the time to pathogen eradication, and the relationship to the time to clinical improvement, between ceftaroline and case-matched vancomycin treated controls in the treatment of adults with serious infections caused by Methicillin-Resistant Staphylococcus aureus (MRSA).

Unknown status26 enrollment criteria

Gamma-Glutamyl Transpeptidase (GGT): A Potential Diagnostic Marker for Helicobacter Pylori Infections...

HELICOBACTER PYLORI INFECTIONS

The investigators hypothesis: Presence of anti-GGT (antibody against GGT) indicates H. pylori infection.

Unknown status4 enrollment criteria
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